STRINGSTRING
PEX26 PEX26 ENSCPOP00000032781 ENSCPOP00000032781 PEX13 PEX13 UBA52 UBA52 HAO1 HAO1 AGPS AGPS IDE IDE MLYCD MLYCD EPHX4 EPHX4 PEX5L PEX5L Nudt8 Nudt8 HSDL2 HSDL2 DPY19L2 DPY19L2 LONP2 LONP2 MEST MEST ECI2 ECI2 LOC100719714 LOC100719714 Rps27a Rps27a TYSND1 TYSND1 DECR2 DECR2 ACOX2 ACOX2 BAAT BAAT FAM185A FAM185A EPHX3 EPHX3 C1orf146 C1orf146 PEX1 PEX1 LOC100732696 LOC100732696 SLC27A2 SLC27A2 PIPOX PIPOX PHYH PHYH H0VAK6_CAVPO H0VAK6_CAVPO AGXT AGXT BTBD8 BTBD8 PEX6 PEX6 AMACR AMACR SUGCT SUGCT HSD17B4 HSD17B4 CROT CROT PECR PECR Paox Paox H0VKT0_CAVPO H0VKT0_CAVPO DPY19L1 DPY19L1 DPY19L3 DPY19L3 CAT CAT ACOT8 ACOT8 IDH1 IDH1 PEX14 PEX14 ACOX1 ACOX1 MPP6 MPP6 Baat Baat NOS2 NOS2 CRAT CRAT DPY19L4 DPY19L4 ACOX3 ACOX3 Phyhd1 Phyhd1 PEX10 PEX10 PEX5 PEX5 H0WAD6_CAVPO H0WAD6_CAVPO GSTK1 GSTK1 H0WDT2_CAVPO H0WDT2_CAVPO UBE2D1 UBE2D1 ENSCPOP00000022046 ENSCPOP00000022046 MPV17 MPV17 PEX2 PEX2 NUDT7 NUDT7 ACOD1 ACOD1 ILVBL ILVBL LOC100729928 LOC100729928 ENSCPOP00000024929 ENSCPOP00000024929 HACL1 HACL1 PEX12 PEX12 PEX7 PEX7 EHHADH EHHADH Acaa1 Acaa1 DDO DDO NUDT19 NUDT19 UBE2D3 UBE2D3 MPV17L MPV17L DAO DAO NRDC NRDC ACOT4 ACOT4 UBB UBB EPHX2 EPHX2 MPP2 MPP2 GNPAT GNPAT LONP1 LONP1 USP9X USP9X ENSCPOP00000031632 ENSCPOP00000031632 Ubc Ubc ZFAND6 ZFAND6 UBE2D2 UBE2D2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX26Peroxisomal biogenesis factor 26. (305 aa)
ENSCPOP00000032781UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
PEX13Peroxisomal biogenesis factor 13. (402 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
AGPSAlkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (658 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa)
MLYCDMalonyl-CoA decarboxylase. (488 aa)
EPHX4Epoxide hydrolase 4. (362 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (650 aa)
Nudt8Nudix hydrolase domain-containing protein. (212 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (440 aa)
DPY19L2Dpy-19 like 2. (553 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
MESTMesoderm specific transcript. (335 aa)
ECI2Enoyl-CoA delta isomerase 2. (354 aa)
LOC100719714Uncharacterized protein. (279 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
TYSND1Trypsin domain containing 1. (570 aa)
DECR22,4-dienoyl-CoA reductase 2. (292 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (709 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (419 aa)
FAM185AFamily with sequence similarity 185 member A. (388 aa)
EPHX3Epoxide hydrolase 3. (314 aa)
C1orf146Chromosome 1 open reading frame 146. (153 aa)
PEX1Peroxisomal biogenesis factor 1. (1271 aa)
LOC100732696Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
SLC27A2Solute carrier family 27 member 2. (619 aa)
PIPOXPipecolic acid and sarcosine oxidase. (390 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (336 aa)
H0VAK6_CAVPOUncharacterized protein. (177 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
BTBD8BTB domain containing 8. (1400 aa)
PEX6Peroxisomal biogenesis factor 6. (982 aa)
AMACRAlpha-methylacyl-CoA racemase. (383 aa)
SUGCTSuccinyl-CoA:glutarate-CoA transferase. (387 aa)
HSD17B4Uncharacterized protein. (713 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (580 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4- dienoyl-CoA reductase activity. (302 aa)
PaoxAmino_oxidase domain-containing protein. (513 aa)
H0VKT0_CAVPOUncharacterized protein. (394 aa)
DPY19L1Dpy-19 like C-mannosyltransferase 1. (648 aa)
DPY19L3Dpy-19 like C-mannosyltransferase 3. (716 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa)
ACOT8Acyl-CoA thioesterase 8. (324 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
PEX14Peroxisomal biogenesis factor 14. (374 aa)
ACOX1Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (660 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (554 aa)
BaatBile_Hydr_Trans domain-containing protein. (47 aa)
NOS2Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1149 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
DPY19L4Dpy-19 like 4. (651 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (737 aa)
Phyhd1Uncharacterized protein. (287 aa)
PEX10Peroxisomal biogenesis factor 10. (325 aa)
PEX5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (538 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
GSTK1Glutathione S-transferase kappa. (226 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
ENSCPOP00000022046Thiolase_N domain-containing protein. (103 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa)
PEX2Peroxisomal biogenesis factor 2. (304 aa)
NUDT7Nudix hydrolase 7. (256 aa)
ACOD1Aconitate decarboxylase 1. (470 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (634 aa)
LOC100729928Uncharacterized protein. (548 aa)
ENSCPOP00000024929SCP2 domain-containing protein. (143 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
PEX12Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (358 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
EHHADHEnoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)
Acaa1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
DDOD-aspartate oxidase. (341 aa)
NUDT19Nudix hydrolase 19. (379 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
MPV17LUncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa)
DAOD-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). (347 aa)
NRDCNardilysin convertase. (1233 aa)
ACOT4Acyl-CoA thioesterase 4. (421 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
EPHX2Epoxide hydrolase 2. (469 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (569 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (1003 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2558 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
UbcUncharacterized protein. (159 aa)
ZFAND6Zinc finger AN1-type containing 6. (207 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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