STRINGSTRING
ZCCHC3 ZCCHC3 PEX5 PEX5 PCNT PCNT H0WAD6_CAVPO H0WAD6_CAVPO NBR1 NBR1 H0WDT2_CAVPO H0WDT2_CAVPO ATG12 ATG12 ENSCPOP00000021762 ENSCPOP00000021762 Plin2 Plin2 Tomm5 Tomm5 ENSCPOP00000022293 ENSCPOP00000022293 TOMM22 TOMM22 UBA52 UBA52 VIM VIM PEX5L PEX5L ARL13B ARL13B TUBA8 TUBA8 MTERF3 MTERF3 FNDC3A FNDC3A DYNC1H1 DYNC1H1 TUBA4A TUBA4A TUBE1 TUBE1 Csnk2a1 Csnk2a1 Rps27a Rps27a PRKN PRKN PARK7 PARK7 TOMM7 TOMM7 CSNK2A2 CSNK2A2 IFT88 IFT88 ULK2 ULK2 ILRUN ILRUN CSNK2B CSNK2B ATM ATM H0VIB7_CAVPO H0VIB7_CAVPO TOMM70 TOMM70 DYNC1LI1 DYNC1LI1 FNDC3B FNDC3B TUBB4B TUBB4B TUBB2B TUBB2B CFTR CFTR TUBA1B TUBA1B USP30 USP30 LOC106026468 LOC106026468 ATG5 ATG5 UBE2V1 UBE2V1 DYNC1I2 DYNC1I2 TOMM40L TOMM40L FUNDC2 FUNDC2 PINK1 PINK1 LOC100727960 LOC100727960 TOMM40 TOMM40 H0VXJ2_CAVPO H0VXJ2_CAVPO LOC100731885 LOC100731885 LOC100732987 LOC100732987 CETN1 CETN1 LOC100716197 LOC100716197 FUNDC1 FUNDC1 MAP1LC3A MAP1LC3A ENSCPOP00000023362 ENSCPOP00000023362 SQSTM1 SQSTM1 Map1lc3b Map1lc3b ENSCPOP00000023749 ENSCPOP00000023749 TUBB4A TUBB4A MFN1 MFN1 DYNLL1 DYNLL1 HDAC6 HDAC6 TOMM20 TOMM20 ENSCPOP00000027005 ENSCPOP00000027005 Ly6g5b Ly6g5b ULK1 ULK1 DYNLL2 DYNLL2 Vdac1 Vdac1 ENSCPOP00000029147 ENSCPOP00000029147 ENSCPOP00000029546 ENSCPOP00000029546 LOC100729187 LOC100729187 PWWP2A PWWP2A PGAM5 PGAM5 UBB UBB TUBB1 TUBB1 ENSCPOP00000030352 ENSCPOP00000030352 ENSCPOP00000030838 ENSCPOP00000030838 CETN3 CETN3 ENSCPOP00000031164 ENSCPOP00000031164 ENSCPOP00000031620 ENSCPOP00000031620 ENSCPOP00000031632 ENSCPOP00000031632 Ubc Ubc TUBB6 TUBB6 TOMM6 TOMM6 DYNC1LI2 DYNC1LI2 MFN2 MFN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZCCHC3Zinc finger CCHC-type containing 3. (394 aa)
PEX5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (538 aa)
PCNTPericentrin. (2941 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
NBR1NBR1 autophagy cargo receptor. (993 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
ENSCPOP00000021762Uncharacterized protein. (105 aa)
Plin2Perilipin; Belongs to the perilipin family. (446 aa)
Tomm5Uncharacterized protein. (51 aa)
ENSCPOP00000022293Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (459 aa)
TOMM22Translocase of outer mitochondrial membrane 22. (142 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
VIMIF rod domain-containing protein; Belongs to the intermediate filament family. (445 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (650 aa)
ARL13BADP ribosylation factor like GTPase 13B. (382 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
MTERF3Mitochondrial transcription termination factor 3. (417 aa)
FNDC3AFibronectin type III domain containing 3A. (1172 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4637 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (478 aa)
Csnk2a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (443 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (349 aa)
IFT88Intraflagellar transport 88. (825 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1033 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (243 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (244 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa)
H0VIB7_CAVPOUncharacterized protein. (439 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (609 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
FNDC3BFibronectin type III domain containing 3B. (1101 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
LOC106026468UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (145 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (638 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (302 aa)
FUNDC2FUN14 domain containing 2. (151 aa)
PINK1PTEN induced kinase 1. (574 aa)
LOC100727960Methyltransf_11 domain-containing protein. (303 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (338 aa)
H0VXJ2_CAVPOUncharacterized protein. (240 aa)
LOC100731885Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
LOC100732987Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
CETN1Centrin 1. (172 aa)
LOC100716197Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
ENSCPOP00000023362UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
SQSTM1Sequestosome 1. (415 aa)
Map1lc3bUncharacterized protein. (126 aa)
ENSCPOP00000023749Uncharacterized protein. (244 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
DYNLL1Dynein light chain. (89 aa)
HDAC6Histone deacetylase 6. (1196 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (145 aa)
ENSCPOP00000027005UBIQUITIN_CONJUGAT_2 domain-containing protein. (83 aa)
Ly6g5bUncharacterized protein. (195 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1037 aa)
DYNLL2Dynein light chain. (89 aa)
Vdac1Uncharacterized protein. (283 aa)
ENSCPOP00000029147Uncharacterized protein. (272 aa)
ENSCPOP00000029546UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
LOC100729187Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
PWWP2APWWP domain containing 2A. (722 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (288 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ENSCPOP00000030352Uncharacterized protein. (97 aa)
ENSCPOP00000030838UBIQUITIN_CONJUGAT_2 domain-containing protein. (133 aa)
CETN3Centrin 3. (163 aa)
ENSCPOP00000031164Perilipin; Belongs to the perilipin family. (376 aa)
ENSCPOP00000031620Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (297 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
UbcUncharacterized protein. (159 aa)
TUBB6Tubulin beta 6 class V; Belongs to the tubulin family. (318 aa)
TOMM6Translocase of outer mitochondrial membrane 6. (74 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (26%) [HD]