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UBE2D1 UBE2D1 ENSCPOP00000023919 ENSCPOP00000023919 RNF7 RNF7 UBE2D3 UBE2D3 CUL5 CUL5 ENSCPOP00000027611 ENSCPOP00000027611 UBB UBB ELOC ELOC ENSCPOP00000031632 ENSCPOP00000031632 GRB2 GRB2 Ubc Ubc UBE2D2 UBE2D2 ENSCPOP00000032781 ENSCPOP00000032781 UBA52 UBA52 TYK2 TYK2 Rps27a Rps27a JAK1 JAK1 SYK SYK CSF3R CSF3R LYN LYN GAB2 GAB2 PTPN11 PTPN11 JAK2 JAK2 CSF3 CSF3 SOCS3 SOCS3 SHC1 SHC1 Elob Elob SOCS1 SOCS1 H0WAD6_CAVPO H0WAD6_CAVPO H0WDT2_CAVPO H0WDT2_CAVPO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
ENSCPOP00000023919Uncharacterized protein. (118 aa)
RNF7Ring finger protein 7. (113 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
CUL5Cullin 5; Belongs to the cullin family. (820 aa)
ENSCPOP00000027611Uncharacterized protein. (421 aa)
UBBPolyubiquitin-B; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...] (229 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
UbcUncharacterized protein. (159 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSCPOP00000032781UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
TYK2Tyrosine-protein kinase. (1174 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
SYKTyrosine-protein kinase. (579 aa)
CSF3RColony stimulating factor 3 receptor. (842 aa)
LYNTyrosine-protein kinase. (512 aa)
GAB2GRB2 associated binding protein 2. (635 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (588 aa)
JAK2Tyrosine-protein kinase. (1035 aa)
CSF3Colony stimulating factor 3. (209 aa)
SOCS3Suppressor of cytokine signaling 3. (228 aa)
SHC1SHC adaptor protein 1. (583 aa)
ElobUbiquitin-like domain-containing protein. (118 aa)
SOCS1Suppressor of cytokine signaling 1. (217 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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