35 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	SCNN1A	Amiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. Belongs to the amilori [...] (680 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	H0W4D7_CAVPO	Taste receptor type 2. (302 aa)
	TAS2R4	Taste receptor type 2. (299 aa)
	TAS2R40	Taste receptor type 2. (323 aa)
	H0W8Y8_CAVPO	Taste receptor type 2. (338 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
	SCN1B	Sodium voltage-gated channel beta subunit 1. (216 aa)
	SCN2B	Sodium voltage-gated channel beta subunit 2. (209 aa)
	TAS1R3	Taste 1 receptor member 3. (898 aa)
	TAS1R2	Taste 1 receptor member 2. (845 aa)
	TAS2R39	Taste receptor type 2. (314 aa)
	Scnn1g	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (653 aa)
	LOC100733322	Taste receptor type 2. (309 aa)
	H0UXB8_CAVPO	Taste receptor type 2. (318 aa)
	SCN2A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
	LOC100734440	Taste receptor type 2. (308 aa)
	SCN4B	Sodium voltage-gated channel beta subunit 4. (184 aa)
	GNB1	Beta-transducin. (340 aa)
	TAS2R16	Taste receptor type 2. (297 aa)
	LOC100730824	Taste receptor type 2. (309 aa)
	TAS2R3	Taste receptor type 2. (311 aa)
	SCN3A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa)
	TAS2R7	Taste receptor type 2. (312 aa)
	TAS1R1	Taste 1 receptor member 1. (850 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	CALHM1	Calcium homeostasis modulator 1. (344 aa)
	Scnn1d	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (618 aa)
	CALHM3	Calcium homeostasis modulator 3. (347 aa)
	Scnn1b	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
	GNAT3	G protein subunit alpha transducin 3. (354 aa)
	H0VVR6_CAVPO	Taste receptor type 2. (295 aa)
	H0VW70_CAVPO	Uncharacterized protein; Belongs to the G-protein coupled receptor T2R family. (146 aa)
	OTOP1	Otopetrin 1. (578 aa)
	TAS2R41	Taste receptor type 2. (308 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALHM1	CALHM3	ENSCPOP00000009856	ENSCPOP00000011821	Calcium homeostasis modulator 1.	Calcium homeostasis modulator 3.	0.710
CALHM1	OTOP1	ENSCPOP00000009856	ENSCPOP00000016037	Calcium homeostasis modulator 1.	Otopetrin 1.	0.568
CALHM1	SCN2A	ENSCPOP00000009856	ENSCPOP00000002443	Calcium homeostasis modulator 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.782
CALHM1	SCN3A	ENSCPOP00000009856	ENSCPOP00000008737	Calcium homeostasis modulator 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.797
CALHM1	TAS1R1	ENSCPOP00000009856	ENSCPOP00000008970	Calcium homeostasis modulator 1.	Taste 1 receptor member 1.	0.426
CALHM1	TAS1R2	ENSCPOP00000009856	ENSCPOP00000031181	Calcium homeostasis modulator 1.	Taste 1 receptor member 2.	0.552
CALHM3	CALHM1	ENSCPOP00000011821	ENSCPOP00000009856	Calcium homeostasis modulator 3.	Calcium homeostasis modulator 1.	0.710
CALHM3	SCN2A	ENSCPOP00000011821	ENSCPOP00000002443	Calcium homeostasis modulator 3.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.455
CALHM3	SCN3A	ENSCPOP00000011821	ENSCPOP00000008737	Calcium homeostasis modulator 3.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.504
GNAT3	GNB1	ENSCPOP00000014659	ENSCPOP00000004992	G protein subunit alpha transducin 3.	Beta-transducin.	0.886
GNAT3	GNB3	ENSCPOP00000014659	ENSCPOP00000017308	G protein subunit alpha transducin 3.	G protein subunit beta 3.	0.980
GNAT3	GNG13	ENSCPOP00000014659	ENSCPOP00000009083	G protein subunit alpha transducin 3.	G protein subunit gamma 13.	0.982
GNAT3	H0UXB8_CAVPO	ENSCPOP00000014659	ENSCPOP00000001730	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.498
GNAT3	H0VVR6_CAVPO	ENSCPOP00000014659	ENSCPOP00000014792	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.498
GNAT3	H0VW70_CAVPO	ENSCPOP00000014659	ENSCPOP00000014948	G protein subunit alpha transducin 3.	Uncharacterized protein; Belongs to the G-protein coupled receptor T2R family.	0.686
GNAT3	H0W4D7_CAVPO	ENSCPOP00000014659	ENSCPOP00000017838	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.498
GNAT3	H0W8Y8_CAVPO	ENSCPOP00000014659	ENSCPOP00000019446	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.498
GNAT3	LOC100730824	ENSCPOP00000014659	ENSCPOP00000006733	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.613
GNAT3	LOC100733322	ENSCPOP00000014659	ENSCPOP00000000035	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.613
GNAT3	LOC100734440	ENSCPOP00000014659	ENSCPOP00000003414	G protein subunit alpha transducin 3.	Taste receptor type 2.	0.613