15 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RDX	Radixin. (604 aa)
	PFN2	Profilin; Belongs to the profilin family. (140 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
	PFN4	Profilin; Belongs to the profilin family. (129 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	PFN3	Profilin; Belongs to the profilin family. (137 aa)
	NEK1	NIMA related kinase 1. (1282 aa)
	LOC101787807	Profilin; Belongs to the profilin family. (153 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	HTT	Huntingtin. (3133 aa)
	EZR	Ezrin. (586 aa)
	CDC42	Cell division cycle 42. (191 aa)
	MSN	Moesin. (577 aa)
	EPS15	Epidermal growth factor receptor pathway substrate 15. (935 aa)
	PFN1	Profilin; Belongs to the profilin family. (140 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	EPS15	ENSCPOP00000031577	ENSCPOP00000030943	Cell division cycle 42.	Epidermal growth factor receptor pathway substrate 15.	0.560
CDC42	EZR	ENSCPOP00000031577	ENSCPOP00000032958	Cell division cycle 42.	Ezrin.	0.752
CDC42	LOC101787807	ENSCPOP00000031577	ENSCPOP00000017706	Cell division cycle 42.	Profilin; Belongs to the profilin family.	0.783
CDC42	MSN	ENSCPOP00000031577	ENSCPOP00000031240	Cell division cycle 42.	Moesin.	0.759
CDC42	PFN1	ENSCPOP00000031577	ENSCPOP00000029499	Cell division cycle 42.	Profilin; Belongs to the profilin family.	0.781
CDC42	PFN2	ENSCPOP00000031577	ENSCPOP00000029474	Cell division cycle 42.	Profilin; Belongs to the profilin family.	0.777
CDC42	PFN3	ENSCPOP00000031577	ENSCPOP00000014499	Cell division cycle 42.	Profilin; Belongs to the profilin family.	0.783
CDC42	PFN4	ENSCPOP00000031577	ENSCPOP00000008689	Cell division cycle 42.	Profilin; Belongs to the profilin family.	0.723
CDC42	RDX	ENSCPOP00000031577	ENSCPOP00000022333	Cell division cycle 42.	Radixin.	0.723
CDC42	SRC	ENSCPOP00000031577	ENSCPOP00000021377	Cell division cycle 42.	Tyrosine-protein kinase.	0.886
CDK2	MYC	ENSCPOP00000008931	ENSCPOP00000025209	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.502
CDK2	NEK1	ENSCPOP00000008931	ENSCPOP00000015085	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	NIMA related kinase 1.	0.409
CDK2	SRC	ENSCPOP00000008931	ENSCPOP00000021377	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.505
EPS15	CDC42	ENSCPOP00000030943	ENSCPOP00000031577	Epidermal growth factor receptor pathway substrate 15.	Cell division cycle 42.	0.560
EZR	CDC42	ENSCPOP00000032958	ENSCPOP00000031577	Ezrin.	Cell division cycle 42.	0.752
EZR	MSN	ENSCPOP00000032958	ENSCPOP00000031240	Ezrin.	Moesin.	0.996
EZR	RDX	ENSCPOP00000032958	ENSCPOP00000022333	Ezrin.	Radixin.	0.992
EZR	SRC	ENSCPOP00000032958	ENSCPOP00000021377	Ezrin.	Tyrosine-protein kinase.	0.409
HTT	LOC101787807	ENSCPOP00000024302	ENSCPOP00000017706	Huntingtin.	Profilin; Belongs to the profilin family.	0.410
HTT	PFN1	ENSCPOP00000024302	ENSCPOP00000029499	Huntingtin.	Profilin; Belongs to the profilin family.	0.476