11 items (Cavia porcellus) - STRING interaction network

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Your Input:
	SLC1A5	Amino acid transporter. (471 aa)
	SLC1A2	Amino acid transporter. (573 aa)
	SLC1A7	Amino acid transporter. (574 aa)
	SLC1A1	Amino acid transporter. (525 aa)
	SLC38A2	Solute carrier family 38 member 2. (509 aa)
	Vegfa	Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa)
	IGF2	Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...] (237 aa)
	IGF1	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (153 aa)
	SLC2A1	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
	SLC1A6	Amino acid transporter. (560 aa)
	SLC1A3	Amino acid transporter. (542 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1	IGF2	ENSCPOP00000031938	ENSCPOP00000027853	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...]	0.785
IGF1	Vegfa	ENSCPOP00000031938	ENSCPOP00000026635	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...]	0.838
IGF2	IGF1	ENSCPOP00000027853	ENSCPOP00000031938	Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...]	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.785
IGF2	SLC1A6	ENSCPOP00000027853	ENSCPOP00000001896	Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...]	Amino acid transporter.	0.403
IGF2	SLC1A7	ENSCPOP00000027853	ENSCPOP00000009609	Insulin-like growth factor II; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is r [...]	Amino acid transporter.	0.411
SLC1A1	SLC1A2	ENSCPOP00000011633	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.712
SLC1A1	SLC1A3	ENSCPOP00000011633	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.916
SLC1A1	SLC1A6	ENSCPOP00000011633	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.919
SLC1A1	SLC1A7	ENSCPOP00000011633	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.912
SLC1A1	SLC2A1	ENSCPOP00000011633	ENSCPOP00000000560	Amino acid transporter.	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.575
SLC1A1	SLC38A2	ENSCPOP00000011633	ENSCPOP00000024513	Amino acid transporter.	Solute carrier family 38 member 2.	0.620
SLC1A2	SLC1A1	ENSCPOP00000007025	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.712
SLC1A2	SLC1A3	ENSCPOP00000007025	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.794
SLC1A2	SLC1A6	ENSCPOP00000007025	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.715
SLC1A2	SLC1A7	ENSCPOP00000007025	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.799
SLC1A2	SLC38A2	ENSCPOP00000007025	ENSCPOP00000024513	Amino acid transporter.	Solute carrier family 38 member 2.	0.528
SLC1A3	SLC1A1	ENSCPOP00000006730	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.916
SLC1A3	SLC1A2	ENSCPOP00000006730	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.794
SLC1A3	SLC1A6	ENSCPOP00000006730	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.910
SLC1A3	SLC1A7	ENSCPOP00000006730	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.911