STRINGSTRING
DBX1 DBX1 HBB HBB TPH2 TPH2 GABRA4 GABRA4 TAC1 TAC1 CHRNA3 CHRNA3 IRX6 IRX6 GABRG1 GABRG1 NHLH2 NHLH2 SLC18A3 SLC18A3 NPR1 NPR1 CHRNB4 CHRNB4 H3F3B H3F3B LOC100735825 LOC100735825 ACTB ACTB NRP2 NRP2 LOC100714163 LOC100714163 KCNMA1 KCNMA1 LOC100730036 LOC100730036
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DBX1Developing brain homeobox 1. (336 aa)
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
TAC1Substance P. (129 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (506 aa)
IRX6Iroquois homeobox 6. (445 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (384 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
SLC18A3Solute carrier family 18 member A3. (533 aa)
NPR1Guanylate cyclase. (881 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (489 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100735825Histone H3; Belongs to the histone H3 family. (136 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
LOC100714163Histone H3; Belongs to the histone H3 family. (136 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
LOC100730036Histone H3. (136 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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