STRINGSTRING
PIKFYVE PIKFYVE EGF EGF MTMR4 MTMR4 NRG1 NRG1 MTMR2 MTMR2 SH3TC2 SH3TC2 LAMP1 LAMP1 GFAP GFAP MBP MBP DNM2 DNM2 LRSAM1 LRSAM1 LAMP2 LAMP2 ENSCPOP00000031025 ENSCPOP00000031025
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2079 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa)
MTMR4Myotubularin related protein 4. (1189 aa)
NRG1Neuregulin 1. (700 aa)
MTMR2Myotubularin related protein 2. (643 aa)
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1287 aa)
LAMP1Lysosomal associated membrane protein 1. (410 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (431 aa)
MBPMyelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity); Belongs to the myelin basic protein family. (194 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (878 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (727 aa)
LAMP2Lysosomal associated membrane protein 2. (408 aa)
ENSCPOP00000031025SAC domain-containing protein. (814 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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