13 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NRG1	Neuregulin 1. (700 aa)
	LAMP2	Lysosomal associated membrane protein 2. (408 aa)
	LRSAM1	Leucine rich repeat and sterile alpha motif containing 1. (727 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (878 aa)
	MBP	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity); Belongs to the myelin basic protein family. (194 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (2079 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (431 aa)
	LAMP1	Lysosomal associated membrane protein 1. (410 aa)
	SH3TC2	SH3 domain and tetratricopeptide repeats 2. (1287 aa)
	MTMR2	Myotubularin related protein 2. (643 aa)
	ENSCPOP00000031025	SAC domain-containing protein. (814 aa)
	MTMR4	Myotubularin related protein 4. (1189 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNM2	SH3TC2	ENSCPOP00000026705	ENSCPOP00000013444	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3 domain and tetratricopeptide repeats 2.	0.449
EGF	GFAP	ENSCPOP00000000697	ENSCPOP00000019373	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.652
EGF	NRG1	ENSCPOP00000000697	ENSCPOP00000007007	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 1.	0.858
ENSCPOP00000031025	LAMP2	ENSCPOP00000031025	ENSCPOP00000029839	SAC domain-containing protein.	Lysosomal associated membrane protein 2.	0.506
ENSCPOP00000031025	MTMR2	ENSCPOP00000031025	ENSCPOP00000007646	SAC domain-containing protein.	Myotubularin related protein 2.	0.914
ENSCPOP00000031025	MTMR4	ENSCPOP00000031025	ENSCPOP00000003101	SAC domain-containing protein.	Myotubularin related protein 4.	0.842
ENSCPOP00000031025	PIKFYVE	ENSCPOP00000031025	ENSCPOP00000023877	SAC domain-containing protein.	Phosphoinositide kinase, FYVE-type zinc finger containing.	0.999
ENSCPOP00000031025	SH3TC2	ENSCPOP00000031025	ENSCPOP00000013444	SAC domain-containing protein.	SH3 domain and tetratricopeptide repeats 2.	0.702
GFAP	EGF	ENSCPOP00000019373	ENSCPOP00000000697	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.652
GFAP	LAMP1	ENSCPOP00000019373	ENSCPOP00000015749	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Lysosomal associated membrane protein 1.	0.433
GFAP	LAMP2	ENSCPOP00000019373	ENSCPOP00000029839	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Lysosomal associated membrane protein 2.	0.450
GFAP	MBP	ENSCPOP00000019373	ENSCPOP00000024960	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity); Belongs to the myelin basic protein family.	0.782
LAMP1	GFAP	ENSCPOP00000015749	ENSCPOP00000019373	Lysosomal associated membrane protein 1.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.433
LAMP1	LAMP2	ENSCPOP00000015749	ENSCPOP00000029839	Lysosomal associated membrane protein 1.	Lysosomal associated membrane protein 2.	0.999
LAMP1	PIKFYVE	ENSCPOP00000015749	ENSCPOP00000023877	Lysosomal associated membrane protein 1.	Phosphoinositide kinase, FYVE-type zinc finger containing.	0.427
LAMP2	ENSCPOP00000031025	ENSCPOP00000029839	ENSCPOP00000031025	Lysosomal associated membrane protein 2.	SAC domain-containing protein.	0.506
LAMP2	GFAP	ENSCPOP00000029839	ENSCPOP00000019373	Lysosomal associated membrane protein 2.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.450
LAMP2	LAMP1	ENSCPOP00000029839	ENSCPOP00000015749	Lysosomal associated membrane protein 2.	Lysosomal associated membrane protein 1.	0.999
LRSAM1	MTMR2	ENSCPOP00000027314	ENSCPOP00000007646	Leucine rich repeat and sterile alpha motif containing 1.	Myotubularin related protein 2.	0.446
LRSAM1	SH3TC2	ENSCPOP00000027314	ENSCPOP00000013444	Leucine rich repeat and sterile alpha motif containing 1.	SH3 domain and tetratricopeptide repeats 2.	0.445