STRINGSTRING
CHTF18 CHTF18 SYCP3 SYCP3 SP3 SP3 REC8 REC8 RFC3 RFC3 RFC5 RFC5 SYCP1 SYCP1 RFC2 RFC2 SPO11 SPO11 RFC4 RFC4 PCNA PCNA ACTB ACTB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHTF18Chromosome transmission fidelity factor 18. (988 aa)
SYCP3Synaptonemal complex protein 3. (169 aa)
SP3Sp3 transcription factor. (690 aa)
REC8REC8 meiotic recombination protein. (599 aa)
RFC3Replication factor C subunit 3. (220 aa)
RFC5Replication factor C subunit 5. (340 aa)
SYCP1Synaptonemal complex protein 1. (931 aa)
RFC2Replication factor C subunit 2. (352 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
RFC4Replication factor C subunit 4. (363 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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