STRINGSTRING
MT1M-2 MT1M-2 MCM2 MCM2 ANXA13 ANXA13 PCNA PCNA MCM10 MCM10 Anxa2 Anxa2 ORC2 ORC2 WRN WRN ANXA7 ANXA7 LOC100723623 LOC100723623 XPA XPA CRISP2 CRISP2 H0VIG8_CAVPO H0VIG8_CAVPO MT4 MT4 ANXA3 ANXA3 RAD51 RAD51 ANXA1 ANXA1 RECQL RECQL ANXA11 ANXA11 TTC4 TTC4 MCM5 MCM5 ANXA6 ANXA6 MT3 MT3 ANXA5 ANXA5 CDC45 CDC45 ANXA4 ANXA4 CDC6 CDC6 MT1M MT1M ANXA9 ANXA9 FEN1 FEN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MT1M-2Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
MCM2DNA helicase; Belongs to the MCM family. (898 aa)
ANXA13Annexin. (315 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (834 aa)
Anxa2Annexin. (339 aa)
ORC2Origin recognition complex subunit 2. (577 aa)
WRNWRN RecQ like helicase. (1462 aa)
ANXA7Annexin. (456 aa)
LOC100723623Annexin. (327 aa)
XPAXPA, DNA damage recognition and repair factor. (263 aa)
CRISP2Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation; Belongs to the CRISP family. (244 aa)
H0VIG8_CAVPOMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
MT4Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
ANXA3Annexin. (323 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ANXA1Annexin. (346 aa)
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (650 aa)
ANXA11Annexin. (499 aa)
TTC4Tetratricopeptide repeat domain 4. (388 aa)
MCM5DNA helicase; Belongs to the MCM family. (731 aa)
ANXA6Annexin. (753 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (66 aa)
ANXA5Annexin. (318 aa)
CDC45Cell division cycle 45. (566 aa)
ANXA4Annexin. (321 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (579 aa)
MT1MMetallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
ANXA9Annexin. (345 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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