13 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	EN2	Homeobox protein engrailed-like. (323 aa)
	CDC42	Cell division cycle 42. (191 aa)
	MSN	Moesin. (577 aa)
	RHOA	Ras homolog family member A. (193 aa)
	EDN1	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa)
	GLB1L3	Beta-galactosidase. (636 aa)
	RDX	Radixin. (604 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	EZR	Ezrin. (586 aa)
	RAC2	Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa)
	ARF6	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	NF1	Neurofibromin 1. (2750 aa)
	GLB1L2	Beta-galactosidase. (652 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	CDC42	ENSCPOP00000007317	ENSCPOP00000031577	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Cell division cycle 42.	0.772
ARF6	EZR	ENSCPOP00000007317	ENSCPOP00000032958	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ezrin.	0.426
ARF6	MSN	ENSCPOP00000007317	ENSCPOP00000031240	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Moesin.	0.433
ARF6	NF1	ENSCPOP00000007317	ENSCPOP00000005513	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Neurofibromin 1.	0.495
ARF6	RAC2	ENSCPOP00000007317	ENSCPOP00000014775	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity).	0.765
ARF6	RDX	ENSCPOP00000007317	ENSCPOP00000022333	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Radixin.	0.415
ARF6	RHOA	ENSCPOP00000007317	ENSCPOP00000031238	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Ras homolog family member A.	0.671
ARF6	SRC	ENSCPOP00000007317	ENSCPOP00000021377	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Tyrosine-protein kinase.	0.478
CDC42	ARF6	ENSCPOP00000031577	ENSCPOP00000007317	Cell division cycle 42.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.772
CDC42	EZR	ENSCPOP00000031577	ENSCPOP00000032958	Cell division cycle 42.	Ezrin.	0.752
CDC42	MSN	ENSCPOP00000031577	ENSCPOP00000031240	Cell division cycle 42.	Moesin.	0.759
CDC42	NF1	ENSCPOP00000031577	ENSCPOP00000005513	Cell division cycle 42.	Neurofibromin 1.	0.515
CDC42	RAC2	ENSCPOP00000031577	ENSCPOP00000014775	Cell division cycle 42.	Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity).	0.941
CDC42	RDX	ENSCPOP00000031577	ENSCPOP00000022333	Cell division cycle 42.	Radixin.	0.723
CDC42	RHOA	ENSCPOP00000031577	ENSCPOP00000031238	Cell division cycle 42.	Ras homolog family member A.	0.973
CDC42	SRC	ENSCPOP00000031577	ENSCPOP00000021377	Cell division cycle 42.	Tyrosine-protein kinase.	0.886
EDN1	RHOA	ENSCPOP00000028977	ENSCPOP00000031238	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Ras homolog family member A.	0.435
EDN1	SRC	ENSCPOP00000028977	ENSCPOP00000021377	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Tyrosine-protein kinase.	0.510
EZR	ARF6	ENSCPOP00000032958	ENSCPOP00000007317	Ezrin.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.426
EZR	CDC42	ENSCPOP00000032958	ENSCPOP00000031577	Ezrin.	Cell division cycle 42.	0.752