Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ART1 | P2rx7 | ENSCPOP00000022204 | ENSCPOP00000018246 | NAD(P)(+)--arginine ADP-ribosyltransferase. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. | 0.509 |
| ART1 | SIRT1 | ENSCPOP00000022204 | ENSCPOP00000000777 | NAD(P)(+)--arginine ADP-ribosyltransferase. | Sirtuin 1. | 0.485 |
| ART1 | SIRT4 | ENSCPOP00000022204 | ENSCPOP00000011117 | NAD(P)(+)--arginine ADP-ribosyltransferase. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.451 |
| ART1 | SIRT5 | ENSCPOP00000022204 | ENSCPOP00000024928 | NAD(P)(+)--arginine ADP-ribosyltransferase. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.486 |
| ART3 | P2rx7 | ENSCPOP00000032173 | ENSCPOP00000018246 | NAD(P)(+)--arginine ADP-ribosyltransferase. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. | 0.450 |
| ART3 | PARG | ENSCPOP00000032173 | ENSCPOP00000012887 | NAD(P)(+)--arginine ADP-ribosyltransferase. | Poly(ADP-ribose) glycohydrolase. | 0.442 |
| ART4 | P2rx7 | ENSCPOP00000004716 | ENSCPOP00000018246 | NAD(P)(+)--arginine ADP-ribosyltransferase. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. | 0.509 |
| ART4 | SIRT1 | ENSCPOP00000004716 | ENSCPOP00000000777 | NAD(P)(+)--arginine ADP-ribosyltransferase. | Sirtuin 1. | 0.485 |
| ART4 | SIRT4 | ENSCPOP00000004716 | ENSCPOP00000011117 | NAD(P)(+)--arginine ADP-ribosyltransferase. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.451 |
| ART4 | SIRT5 | ENSCPOP00000004716 | ENSCPOP00000024928 | NAD(P)(+)--arginine ADP-ribosyltransferase. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.486 |
| ART5 | P2rx7 | ENSCPOP00000000169 | ENSCPOP00000018246 | NAD(P)(+)--arginine ADP-ribosyltransferase. | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. | 0.478 |
| ART5 | SIRT1 | ENSCPOP00000000169 | ENSCPOP00000000777 | NAD(P)(+)--arginine ADP-ribosyltransferase. | Sirtuin 1. | 0.495 |
| ART5 | SIRT4 | ENSCPOP00000000169 | ENSCPOP00000011117 | NAD(P)(+)--arginine ADP-ribosyltransferase. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.422 |
| ART5 | SIRT5 | ENSCPOP00000000169 | ENSCPOP00000024928 | NAD(P)(+)--arginine ADP-ribosyltransferase. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.541 |
| Glud1 | SIRT1 | ENSCPOP00000004647 | ENSCPOP00000000777 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Sirtuin 1. | 0.682 |
| Glud1 | SIRT3 | ENSCPOP00000004647 | ENSCPOP00000018954 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.701 |
| Glud1 | SIRT4 | ENSCPOP00000004647 | ENSCPOP00000011117 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] | 0.954 |
| Glud1 | SIRT5 | ENSCPOP00000004647 | ENSCPOP00000024928 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] | 0.686 |
| MACROD1 | PARG | ENSCPOP00000010540 | ENSCPOP00000012887 | Mono-ADP ribosylhydrolase 1. | Poly(ADP-ribose) glycohydrolase. | 0.669 |
| MACROD1 | PARP10 | ENSCPOP00000010540 | ENSCPOP00000012825 | Mono-ADP ribosylhydrolase 1. | Poly [ADP-ribose] polymerase. | 0.432 |
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