STRINGSTRING
ATP8B1 ATP8B1 ELMOD1 ELMOD1 USH2A USH2A ELMOD3 ELMOD3 GSN GSN IFT88 IFT88 LOXHD1 LOXHD1 VANGL2 VANGL2 KIF3A KIF3A DCHS1 DCHS1 TMC2 TMC2 OTOGL OTOGL KCNQ1 KCNQ1 CEACAM16 CEACAM16 CLDN9 CLDN9 CLDN6 CLDN6 PVALB PVALB MYO7A MYO7A ACTB ACTB RDX RDX ALMS1 ALMS1 Tbc1d24 Tbc1d24 Tjp2 Tjp2 SEC24B SEC24B KCNE1 KCNE1 EPS8 EPS8 SMURF2 SMURF2 CLRN1 CLRN1 KCNJ10 KCNJ10 SCRIB SCRIB Triobp Triobp ENSCPOP00000028385 ENSCPOP00000028385 CLIC5 CLIC5 VANGL1 VANGL1 PTK7 PTK7 MYO3B MYO3B EZR EZR SMURF1 SMURF1 TTC8 TTC8 WHRN WHRN Pdzd7 Pdzd7 CIB2 CIB2 ESPN ESPN OTOG OTOG TMC1 TMC1 FAT4 FAT4 EPS8L2 EPS8L2 KCNQ4 KCNQ4 USH1G USH1G CLDN14 CLDN14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1146 aa)
ELMOD1ELMO domain containing 1. (326 aa)
USH2AUsherin. (5190 aa)
ELMOD3ELMO domain containing 3. (381 aa)
GSNGelsolin. (775 aa)
IFT88Intraflagellar transport 88. (825 aa)
LOXHD1Lipoxygenase homology domains 1. (2070 aa)
VANGL2Vang-like protein. (548 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (728 aa)
DCHS1Dachsous cadherin-related 1. (3297 aa)
TMC2Transmembrane channel-like protein. (868 aa)
OTOGLOtogelin like. (2177 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
CEACAM16Carcinoembryonic antigen related cell adhesion molecule 16. (424 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
PVALBParvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity). (110 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2203 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
RDXRadixin. (604 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (3698 aa)
Tbc1d24Uncharacterized protein. (561 aa)
Tjp2Uncharacterized protein; Belongs to the MAGUK family. (1176 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1224 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (821 aa)
SMURF2E3 ubiquitin-protein ligase. (782 aa)
CLRN1Clarin 1. (232 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
SCRIBScribble planar cell polarity protein. (1653 aa)
TriobpPH domain-containing protein. (630 aa)
ENSCPOP00000028385TPR_REGION domain-containing protein. (154 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
VANGL1Vang-like protein. (522 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1063 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1306 aa)
EZREzrin. (586 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
WHRNWhirlin. (916 aa)
Pdzd7Uncharacterized protein. (553 aa)
CIB2Calcium and integrin binding family member 2. (187 aa)
ESPNEspin. (870 aa)
OTOGOtogelin. (2777 aa)
TMC1Transmembrane channel-like protein. (761 aa)
FAT4FAT atypical cadherin 4. (4796 aa)
EPS8L2EPS8 like 2. (717 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (699 aa)
USH1GUSH1 protein network component sans. (462 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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