7 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOA	Ras homolog family member A. (193 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1371 aa)
	RDX	Radixin. (604 aa)
	MSN	Moesin. (577 aa)
	Gapdh	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (353 aa)
	EZR	Ezrin. (586 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EZR	MSN	ENSCPOP00000032958	ENSCPOP00000031240	Ezrin.	Moesin.	0.996
EZR	RDX	ENSCPOP00000032958	ENSCPOP00000022333	Ezrin.	Radixin.	0.992
EZR	RHOA	ENSCPOP00000032958	ENSCPOP00000031238	Ezrin.	Ras homolog family member A.	0.690
EZR	ROCK1	ENSCPOP00000032958	ENSCPOP00000009405	Ezrin.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.410
EZR	ROCK2	ENSCPOP00000032958	ENSCPOP00000011391	Ezrin.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.647
Gapdh	RHOA	ENSCPOP00000032190	ENSCPOP00000031238	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Ras homolog family member A.	0.491
MSN	EZR	ENSCPOP00000031240	ENSCPOP00000032958	Moesin.	Ezrin.	0.996
MSN	RDX	ENSCPOP00000031240	ENSCPOP00000022333	Moesin.	Radixin.	0.978
MSN	RHOA	ENSCPOP00000031240	ENSCPOP00000031238	Moesin.	Ras homolog family member A.	0.697
MSN	ROCK2	ENSCPOP00000031240	ENSCPOP00000011391	Moesin.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.661
RDX	EZR	ENSCPOP00000022333	ENSCPOP00000032958	Radixin.	Ezrin.	0.992
RDX	MSN	ENSCPOP00000022333	ENSCPOP00000031240	Radixin.	Moesin.	0.978
RDX	RHOA	ENSCPOP00000022333	ENSCPOP00000031238	Radixin.	Ras homolog family member A.	0.688
RDX	ROCK1	ENSCPOP00000022333	ENSCPOP00000009405	Radixin.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.653
RDX	ROCK2	ENSCPOP00000022333	ENSCPOP00000011391	Radixin.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.595
RHOA	EZR	ENSCPOP00000031238	ENSCPOP00000032958	Ras homolog family member A.	Ezrin.	0.690
RHOA	Gapdh	ENSCPOP00000031238	ENSCPOP00000032190	Ras homolog family member A.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.491
RHOA	MSN	ENSCPOP00000031238	ENSCPOP00000031240	Ras homolog family member A.	Moesin.	0.697
RHOA	RDX	ENSCPOP00000031238	ENSCPOP00000022333	Ras homolog family member A.	Radixin.	0.688
RHOA	ROCK1	ENSCPOP00000031238	ENSCPOP00000009405	Ras homolog family member A.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.992