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| | KCNB1 | Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa) |
| | GIPR | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (455 aa) |
| | KCNH1 | Uncharacterized protein. (989 aa) |
| | TRPC1 | Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (810 aa) |
| | SYT2 | Synaptotagmin 2. (421 aa) |
| | STX1A | Syntaxin 1A; Belongs to the syntaxin family. (288 aa) |
| | STIM2 | Stromal interaction molecule 2. (742 aa) |
| | GRIA3 | Glutamate ionotropic receptor AMPA type subunit 3. (888 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa) |
| | GRIA1 | Glutamate ionotropic receptor AMPA type subunit 1. (861 aa) |
| | SCN4B | Sodium voltage-gated channel beta subunit 4. (184 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | GAD1 | Glutamate decarboxylase 1. (594 aa) |
| | SLC1A5 | Amino acid transporter. (471 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa) |
| | Glud1 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (540 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1754 aa) |
| | GABRB3 | Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa) |
| | CADPS2 | Calcium dependent secretion activator 2. (1179 aa) |
| | BEST1 | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (566 aa) |
| | SLC7A5 | Solute carrier family 7 member 5. (477 aa) |
| | CALCR | Calcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. (474 aa) |
| | ANO8 | Anoctamin. (1034 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | RAB3B | RAB3B, member RAS oncogene family. (219 aa) |
| | SLC1A2 | Amino acid transporter. (573 aa) |
| | UNC13C | Unc-13 homolog C. (2198 aa) |
| | SLC6A11 | Solute carrier family 6 member 11. (640 aa) |
| | SYT13 | Synaptotagmin 13. (373 aa) |
| | SENP1 | SUMO specific peptidase 1. (638 aa) |
| | ERC1 | ELKS/RAB6-interacting/CAST family member 1. (1116 aa) |
| | SLC1A4 | Solute carrier family 1 member 4. (532 aa) |
| | SST | Somatostatin. (116 aa) |
| | IAPP | Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family. (92 aa) |
| | SLC38A4 | Solute carrier family 38 member 4. (547 aa) |
| | TRPV1 | Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits [...] (839 aa) |
| | TRPM5 | Transient receptor potential cation channel subfamily M member 5. (1159 aa) |
| | KCNJ6 | Potassium voltage-gated channel subfamily J member 6. (429 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (347 aa) |
| | SLC1A7 | Amino acid transporter. (574 aa) |
| | STX2 | Syntaxin 2; Belongs to the syntaxin family. (286 aa) |
| | TRPM6 | Transient receptor potential cation channel subfamily M member 6. (1902 aa) |
| | SLC5A2 | Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa) |
| | KCNJ8 | Uncharacterized protein. (468 aa) |
| | GLRA3 | Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2337 aa) |
| | SYTL1 | Synaptotagmin like 1. (558 aa) |
| | KCNG3 | Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (417 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) |
| | CHRNA5 | Cholinergic receptor nicotinic alpha 5 subunit. (438 aa) |
| | CHRNA3 | Cholinergic receptor nicotinic alpha 3 subunit. (506 aa) |
| | UNC13D | Unc-13 homolog D. (1100 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa) |
| | SLC6A17 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa) |
| | SLC1A1 | Amino acid transporter. (525 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1371 aa) |
| | SIK2 | Salt inducible kinase 2. (883 aa) |
| | P2RX2 | P2X purinoceptor 2; Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity); Belongs to the P2X receptor family. (411 aa) |
| | SLC6A13 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (601 aa) |
| | ANO5 | Anoctamin. (886 aa) |
| | Kcnj13 | Inward rectifier potassium channel 13; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependen [...] (352 aa) |
| | KCNIP1 | Potassium voltage-gated channel interacting protein 1. (227 aa) |
| | SLC12A2 | Solute carrier family 12 member 2. (1136 aa) |
| | VAMP4 | Vesicle associated membrane protein 4. (163 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa) |
| | MCU | Mitochondrial calcium uniporter. (344 aa) |
| | SCN8A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa) |
| | PPY | Pancreatic icosapeptide-like; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. (126 aa) |
| | GCG | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa) |
| | Kcnj12 | Uncharacterized protein. (535 aa) |
| | KCNJ14 | Inwardly-rectifying potassium channel Kir2.4. (439 aa) |
| | SSTR1 | Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa) |
| | KCNJ4 | Uncharacterized protein. (443 aa) |
| | GCGR | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (481 aa) |
| | SYT3 | Synaptotagmin 3. (587 aa) |
| | STXBP2 | Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (593 aa) |
| | SSTR5 | Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (365 aa) |
| | P2RY11 | Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (408 aa) |
| | Chrm3 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa) |
| | GABRA2 | Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa) |
| | KCNC3 | Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa) |
| | ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. (418 aa) |
| | KCNJ1 | Potassium voltage-gated channel subfamily J member 1. (376 aa) |
| | CHRM4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa) |
| | DOC2B | Double C2 domain beta. (340 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | RIMBP2 | RIMS binding protein 2. (830 aa) |
| | ANO10 | Anoctamin. (661 aa) |
| | ADRA1B | Adrenoceptor alpha 1B. (520 aa) |
| | TRPM4 | Transient receptor potential cation channel subfamily M member 4. (1138 aa) |
| | SCN1B | Sodium voltage-gated channel beta subunit 1. (216 aa) |
| | CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1078 aa) |
| | CCK | Cholecystokinin. (115 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (211 aa) |
| | ORAI3 | ORAI calcium release-activated calcium modulator 3. (297 aa) |
| | MTPN | Myotrophin. (118 aa) |
| | CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa) |
| | CACNB1 | Calcium voltage-gated channel auxiliary subunit beta 1. (641 aa) |
| | TRPM3 | Transient receptor potential cation channel subfamily M member 3. (1721 aa) |
| | STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (570 aa) |
| | SLC38A2 | Solute carrier family 38 member 2. (509 aa) |
| | CDKAL1 | CDK5 regulatory subunit associated protein 1 like 1. (548 aa) |
| | SCN3B | Sodium voltage-gated channel beta subunit 3. (215 aa) |
| | STX5 | Syntaxin 5; Belongs to the syntaxin family. (355 aa) |
| | STIM1 | Stromal interaction molecule 1. (713 aa) |
| | Sstr2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | VAMP3 | Vesicle associated membrane protein 3. (100 aa) |
| | CPLX1 | Complexin 1. (134 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (878 aa) |
| | KCNJ5 | Potassium voltage-gated channel subfamily J member 5. (419 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | KCNMA1 | Potassium calcium-activated channel subfamily M alpha 1. (1133 aa) |
| | SUMO1 | Small ubiquitin-related modifier. (101 aa) |
| | RYR3 | Ryanodine receptor 3. (4843 aa) |
| | ANO1 | Anoctamin. (1011 aa) |
| | ANO6 | Anoctamin. (922 aa) |
| | KCNA2 | Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa) |
| | SLC1A6 | Amino acid transporter. (560 aa) |
| | STX3 | Syntaxin 3; Belongs to the syntaxin family. (288 aa) |
| | ATP12A | Potassium-transporting ATPase alpha chain 2; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues. (1072 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa) |
| | NALCN | Sodium leak channel, non-selective. (1738 aa) |
| | GCK | Phosphotransferase. (414 aa) |
| | GLRB | Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa) |
| | ORAI2 | ORAI calcium release-activated calcium modulator 2. (307 aa) |
| | KCNJ16 | Inwardly-rectifying potassium channel Kir5.1. (419 aa) |
| | TFB1M | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (346 aa) |
| | Chrnb2 | Uncharacterized protein. (499 aa) |
| | Vamp2 | V-SNARE coiled-coil homology domain-containing protein. (164 aa) |
| | Kcnj2 | Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa) |
| | KCND1 | Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2164 aa) |
| | SCN5A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa) |
| | SYT7 | Synaptotagmin 7. (556 aa) |
| | SSTR3 | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (432 aa) |
| | BEST3 | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (673 aa) |
| | SYT1 | Synaptotagmin 1. (422 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | KCND3 | Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa) |
| | GRIK2 | Glutamate ionotropic receptor kainate type subunit 2. (908 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (101 aa) |
| | RAB3C | RAB3C, member RAS oncogene family. (227 aa) |
| | TRPC3 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (849 aa) |
| | GRIA4 | Glutamate ionotropic receptor AMPA type subunit 4. (819 aa) |
| | CLCN3 | H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily. (865 aa) |
| | KCNB2 | Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa) |
| | GRIA2 | Glutamate ionotropic receptor AMPA type subunit 2. (883 aa) |
| | GRM4 | Glutamate metabotropic receptor 4. (893 aa) |
| | GALR1 | Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa) |
