STRINGSTRING
ANXA9 ANXA9 LOC100723623 LOC100723623 ANXA7 ANXA7 Anxa2 Anxa2 ANXA13 ANXA13 ATM ATM ANXA3 ANXA3 Brca1 Brca1 ANXA1 ANXA1 ANXA11 ANXA11 UNG UNG ANXA6 ANXA6 ACTB ACTB ANXA5 ANXA5 CBX6 CBX6 ANXA4 ANXA4 UNG-2 UNG-2 CBX7 CBX7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANXA9Annexin. (345 aa)
LOC100723623Annexin. (327 aa)
ANXA7Annexin. (456 aa)
Anxa2Annexin. (339 aa)
ANXA13Annexin. (315 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa)
ANXA3Annexin. (323 aa)
Brca1Uncharacterized protein. (79 aa)
ANXA1Annexin. (346 aa)
ANXA11Annexin. (499 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (298 aa)
ANXA6Annexin. (753 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
ANXA5Annexin. (318 aa)
CBX6Chromobox 6. (415 aa)
ANXA4Annexin. (321 aa)
UNG-2Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (311 aa)
CBX7Chromobox 7. (228 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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