STRINGSTRING
PFN3 PFN3 CD19 CD19 LOC100723623 LOC100723623 ANXA7 ANXA7 Alb Alb Anxa2 Anxa2 PFN4 PFN4 ANXA13 ANXA13 ANXA3 ANXA3 CD34 CD34 ANXA9 ANXA9 CAV3 CAV3 PFN1 PFN1 PFN2 PFN2 CAV1 CAV1 Cav2 Cav2 ANXA4 ANXA4 ANXA5 ANXA5 Sp100 Sp100 ANXA1 ANXA1 ANXA6 ANXA6 LOC101787807 LOC101787807 ANXA11 ANXA11 SLC5A3 SLC5A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PFN3Profilin; Belongs to the profilin family. (137 aa)
CD19B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...] (536 aa)
LOC100723623Annexin. (327 aa)
ANXA7Annexin. (456 aa)
AlbPreproalbumin. (608 aa)
Anxa2Annexin. (339 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
ANXA13Annexin. (315 aa)
ANXA3Annexin. (323 aa)
CD34CD34 molecule. (389 aa)
ANXA9Annexin. (345 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
PFN2Profilin; Belongs to the profilin family. (140 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (125 aa)
ANXA4Annexin. (321 aa)
ANXA5Annexin. (318 aa)
Sp100Uncharacterized protein. (829 aa)
ANXA1Annexin. (346 aa)
ANXA6Annexin. (753 aa)
LOC101787807Profilin; Belongs to the profilin family. (153 aa)
ANXA11Annexin. (499 aa)
SLC5A3Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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