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TNNI2 TNNI2 ADRM1 ADRM1 ALDH3B2 ALDH3B2 ACTN3 ACTN3 PARK7 PARK7 UMPS UMPS TPI1 TPI1 MYL3 MYL3 LTA4H LTA4H ENO3 ENO3 ALDH3A1 ALDH3A1 ALDH3B1 ALDH3B1 ALDH3A2 ALDH3A2 IGFBP7 IGFBP7 ALDH7A1 ALDH7A1 Gapdh Gapdh ACTA1 ACTA1 ACLY ACLY FABP5 FABP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNNI2Troponin I2, fast skeletal type. (190 aa)
ADRM1Adhesion regulating molecule 1. (407 aa)
ALDH3B2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (889 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
UMPSUridine monophosphate synthetase. (480 aa)
TPI1Triosephosphate isomerase. (249 aa)
MYL3Myosin light chain 3. (199 aa)
LTA4HLeukotriene A-4 hydrolase; Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. (611 aa)
ENO3Enolase 3. (434 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
IGFBP7Insulin like growth factor binding protein 7. (296 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (539 aa)
GapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (353 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
FABP5E-FABP; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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