STRINGSTRING
Anxa2 Anxa2 LOC100723623 LOC100723623 ANXA7 ANXA7 ANXA13 ANXA13 ANXA3 ANXA3 ANXA1 ANXA1 ANXA11 ANXA11 ANXA6 ANXA6 ANXA5 ANXA5 ANXA4 ANXA4 ANXA9 ANXA9 IL10 IL10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Anxa2Annexin. (339 aa)
LOC100723623Annexin. (327 aa)
ANXA7Annexin. (456 aa)
ANXA13Annexin. (315 aa)
ANXA3Annexin. (323 aa)
ANXA1Annexin. (346 aa)
ANXA11Annexin. (499 aa)
ANXA6Annexin. (753 aa)
ANXA5Annexin. (318 aa)
ANXA4Annexin. (321 aa)
ANXA9Annexin. (345 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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