STRINGSTRING
SLC1A2 SLC1A2 SLC1A6 SLC1A6 GLS2 GLS2 SLC1A5 SLC1A5 SLC1A3 SLC1A3 SLC1A7 SLC1A7 SLC1A1 SLC1A1 NNMT NNMT GCG GCG GCGR GCGR ACTB ACTB MAFB MAFB DPP4 DPP4 INS INS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC1A2Amino acid transporter. (573 aa)
SLC1A6Amino acid transporter. (560 aa)
GLS2Glutaminase 2. (558 aa)
SLC1A5Amino acid transporter. (471 aa)
SLC1A3Amino acid transporter. (542 aa)
SLC1A7Amino acid transporter. (574 aa)
SLC1A1Amino acid transporter. (525 aa)
NNMTNicotinamide N-methyltransferase. (264 aa)
GCGGlicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (481 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
MAFBMAF bZIP transcription factor B. (326 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (764 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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