STRINGSTRING
LOC100723623 LOC100723623 F3 F3 ANXA7 ANXA7 REN REN TFPI2 TFPI2 ANXA1 ANXA1 ANXA3 ANXA3 PLG PLG ANXA13 ANXA13 Anxa2 Anxa2 VTN VTN ANXA11 ANXA11 HRG HRG THBD THBD ANXA6 ANXA6 ANXA5 ANXA5 ANXA4 ANXA4 LOC100733619 LOC100733619 INS INS TLR7 TLR7 ATP12A ATP12A ANXA9 ANXA9 VWF VWF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100723623Annexin. (327 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (289 aa)
ANXA7Annexin. (456 aa)
RENRenin; Belongs to the peptidase A1 family. (403 aa)
TFPI2Tissue factor pathway inhibitor. (243 aa)
ANXA1Annexin. (346 aa)
ANXA3Annexin. (323 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
ANXA13Annexin. (315 aa)
Anxa2Annexin. (339 aa)
VTNSMB domain-containing protein. (482 aa)
ANXA11Annexin. (499 aa)
HRGHistidine rich glycoprotein. (467 aa)
THBDThrombomodulin. (534 aa)
ANXA6Annexin. (753 aa)
ANXA5Annexin. (318 aa)
ANXA4Annexin. (321 aa)
LOC100733619Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (258 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
TLR7Toll like receptor 7. (1049 aa)
ATP12APotassium-transporting ATPase alpha chain 2; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues. (1072 aa)
ANXA9Annexin. (345 aa)
VWFUncharacterized protein. (2833 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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