11 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (481 aa)
	SLC1A6	Amino acid transporter. (560 aa)
	SLC1A5	Amino acid transporter. (471 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	SLC1A2	Amino acid transporter. (573 aa)
	SLC1A7	Amino acid transporter. (574 aa)
	SLC1A1	Amino acid transporter. (525 aa)
	INSR	Tyrosine-protein kinase receptor. (1371 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	GCGR	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (481 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCGR	GLP1R	ENSCPOP00000016190	ENSCPOP00000013921	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.712
GCGR	INS	ENSCPOP00000016190	ENSCPOP00000026989	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.484
GLP1R	GCGR	ENSCPOP00000013921	ENSCPOP00000016190	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.	0.712
GLP1R	INS	ENSCPOP00000013921	ENSCPOP00000026989	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.674
INS	GCGR	ENSCPOP00000026989	ENSCPOP00000016190	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.	0.484
INS	GLP1R	ENSCPOP00000026989	ENSCPOP00000013921	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.674
INS	INSR	ENSCPOP00000026989	ENSCPOP00000011692	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.998
INSR	INS	ENSCPOP00000011692	ENSCPOP00000026989	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.998
SLC1A1	SLC1A2	ENSCPOP00000011633	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.712
SLC1A1	SLC1A3	ENSCPOP00000011633	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.916
SLC1A1	SLC1A6	ENSCPOP00000011633	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.919
SLC1A1	SLC1A7	ENSCPOP00000011633	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.912
SLC1A2	SLC1A1	ENSCPOP00000007025	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.712
SLC1A2	SLC1A3	ENSCPOP00000007025	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.794
SLC1A2	SLC1A6	ENSCPOP00000007025	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.715
SLC1A2	SLC1A7	ENSCPOP00000007025	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.799
SLC1A3	SLC1A1	ENSCPOP00000006730	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.916
SLC1A3	SLC1A2	ENSCPOP00000006730	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.794
SLC1A3	SLC1A6	ENSCPOP00000006730	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.910
SLC1A3	SLC1A7	ENSCPOP00000006730	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.911