(8 nodes) (2021) A Comparative Review of the Cell Biology, Biochemistry, and Genetics of Lactose Synthesis. network (Cavia porcellus)

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Your Input:
	SLC35A2	Solute carrier family 35 member A2. (397 aa)
	UGP2	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	TMEM165	GDT1 family protein. (324 aa)
	GALK2	Galactokinase 2. (458 aa)
	Lalba	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family. (142 aa)
	GALE	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
	SLC2A9	Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (554 aa)
	B4GALT1	Beta-1,4-galactosyltransferase 1. (324 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4GALT1	GALE	ENSCPOP00000023155	ENSCPOP00000022292	Beta-1,4-galactosyltransferase 1.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.948
B4GALT1	Lalba	ENSCPOP00000023155	ENSCPOP00000019835	Beta-1,4-galactosyltransferase 1.	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	0.997
B4GALT1	SLC35A2	ENSCPOP00000023155	ENSCPOP00000025966	Beta-1,4-galactosyltransferase 1.	Solute carrier family 35 member A2.	0.415
B4GALT1	TMEM165	ENSCPOP00000023155	ENSCPOP00000010616	Beta-1,4-galactosyltransferase 1.	GDT1 family protein.	0.461
B4GALT1	UGP2	ENSCPOP00000023155	ENSCPOP00000027441	Beta-1,4-galactosyltransferase 1.	UTP--glucose-1-phosphate uridylyltransferase.	0.441
GALE	B4GALT1	ENSCPOP00000022292	ENSCPOP00000023155	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Beta-1,4-galactosyltransferase 1.	0.948
GALE	GALK2	ENSCPOP00000022292	ENSCPOP00000031948	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Galactokinase 2.	0.997
GALE	Lalba	ENSCPOP00000022292	ENSCPOP00000019835	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	0.942
GALE	SLC35A2	ENSCPOP00000022292	ENSCPOP00000025966	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Solute carrier family 35 member A2.	0.587
GALE	UGP2	ENSCPOP00000022292	ENSCPOP00000027441	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UTP--glucose-1-phosphate uridylyltransferase.	0.979
GALK2	GALE	ENSCPOP00000031948	ENSCPOP00000022292	Galactokinase 2.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.997
GALK2	SLC2A9	ENSCPOP00000031948	ENSCPOP00000024612	Galactokinase 2.	Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.410
GALK2	SLC35A2	ENSCPOP00000031948	ENSCPOP00000025966	Galactokinase 2.	Solute carrier family 35 member A2.	0.436
GALK2	UGP2	ENSCPOP00000031948	ENSCPOP00000027441	Galactokinase 2.	UTP--glucose-1-phosphate uridylyltransferase.	0.881
Lalba	B4GALT1	ENSCPOP00000019835	ENSCPOP00000023155	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	Beta-1,4-galactosyltransferase 1.	0.997
Lalba	GALE	ENSCPOP00000019835	ENSCPOP00000022292	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.942
Lalba	UGP2	ENSCPOP00000019835	ENSCPOP00000027441	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	UTP--glucose-1-phosphate uridylyltransferase.	0.456
SLC2A9	GALK2	ENSCPOP00000024612	ENSCPOP00000031948	Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	Galactokinase 2.	0.410
SLC2A9	SLC35A2	ENSCPOP00000024612	ENSCPOP00000025966	Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	Solute carrier family 35 member A2.	0.409
SLC2A9	UGP2	ENSCPOP00000024612	ENSCPOP00000027441	Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	UTP--glucose-1-phosphate uridylyltransferase.	0.547