STRINGSTRING
ADAMDEC1 ADAMDEC1 RHBDF1 RHBDF1 CD44 CD44 IL2 IL2 RACK1 RACK1 CCL20 CCL20 ADAM17 ADAM17 THRSP THRSP ACKR3 ACKR3 ACOX1 ACOX1 PAK6 PAK6 SPTA1 SPTA1 BIRC3 BIRC3 PCDHGA6 PCDHGA6 CPT1A CPT1A CCR6 CCR6 TNFSF18 TNFSF18 CHST11 CHST11 DSG4 DSG4 ECT2 ECT2 RGS14 RGS14 TNF TNF EMP3 EMP3 PPARA PPARA VWF VWF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADAMDEC1ADAM like decysin 1. (471 aa)
RHBDF1Rhomboid 5 homolog 1. (891 aa)
CD44CD44 molecule (Indian blood group). (660 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
CCL20C-C motif chemokine. (96 aa)
ADAM17ADAM metallopeptidase domain 17. (826 aa)
THRSPThyroid hormone responsive. (145 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ACOX1Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (660 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2415 aa)
BIRC3Baculoviral IAP repeat containing 3. (600 aa)
PCDHGA6Protocadherin gamma subfamily A, 6. (957 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (376 aa)
TNFSF18Tumor necrosis factor ligand 2A. (199 aa)
CHST11Carbohydrate sulfotransferase. (312 aa)
DSG4Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1043 aa)
ECT2Epithelial cell transforming 2. (913 aa)
RGS14Regulator of G protein signaling 14. (570 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
EMP3Epithelial membrane protein 3; Probably involved in cell proliferation and cell-cell interactions; Belongs to the PMP-22/EMP/MP20 family. (163 aa)
PPARAPeroxisome proliferator-activated receptor alpha; Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn- glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and [...] (467 aa)
VWFUncharacterized protein. (2833 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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