STRINGSTRING
ANXA7 ANXA7 LOC100723623 LOC100723623 TOP3B TOP3B TOP3A TOP3A ANXA9 ANXA9 BECN1 BECN1 CCND1 CCND1 ANXA4 ANXA4 STAT3 STAT3 ANXA5 ANXA5 ANXA6 ANXA6 BCL2 BCL2 ANXA11 ANXA11 AR AR ANXA1 ANXA1 Skp2 Skp2 ANXA3 ANXA3 CASP9 CASP9 ANXA13 ANXA13 Anxa2 Anxa2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANXA7Annexin. (456 aa)
LOC100723623Annexin. (327 aa)
TOP3BDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (862 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1027 aa)
ANXA9Annexin. (345 aa)
BECN1Beclin 1. (448 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ANXA4Annexin. (321 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ANXA5Annexin. (318 aa)
ANXA6Annexin. (753 aa)
BCL2BCL2 apoptosis regulator. (183 aa)
ANXA11Annexin. (499 aa)
ARAndrogen receptor. (926 aa)
ANXA1Annexin. (346 aa)
Skp2F-box domain-containing protein. (424 aa)
ANXA3Annexin. (323 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (447 aa)
ANXA13Annexin. (315 aa)
Anxa2Annexin. (339 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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