STRINGSTRING
SCNN1A SCNN1A MB MB ETHE1 ETHE1 SLC1A6 SLC1A6 HMOX2 HMOX2 SLC1A5 SLC1A5 CARS1 CARS1 CRYZ CRYZ SLC1A3 SLC1A3 SLC1A2 SLC1A2 SLC1A7 SLC1A7 Trpa1 Trpa1 SLC1A1 SLC1A1 Txn Txn H0W1R6_CAVPO H0W1R6_CAVPO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. Belongs to the amilori [...] (680 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
ETHE1ETHE1 persulfide dioxygenase. (227 aa)
SLC1A6Amino acid transporter. (560 aa)
HMOX2Heme oxygenase 2. (316 aa)
SLC1A5Amino acid transporter. (471 aa)
CARS1Cysteinyl-tRNA synthetase. (831 aa)
CRYZQuinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding. (329 aa)
SLC1A3Amino acid transporter. (542 aa)
SLC1A2Amino acid transporter. (573 aa)
SLC1A7Amino acid transporter. (574 aa)
Trpa1ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (991 aa)
SLC1A1Amino acid transporter. (525 aa)
TxnThioredoxin; Belongs to the thioredoxin family. (105 aa)
H0W1R6_CAVPOThioredoxin; Belongs to the thioredoxin family. (106 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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