8 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	KCNQ2	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (871 aa)
	EMX1	Empty spiracles homeobox 1. (258 aa)
	PVALB	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity). (110 aa)
	SV2A	Synaptic vesicle glycoprotein 2A. (742 aa)
	SST	Somatostatin. (116 aa)
	KCNQ3	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (860 aa)
	SCN1A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa)
	KCNQ5	Potassium voltage-gated channel subfamily Q member 5. (908 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EMX1	PVALB	ENSCPOP00000032459	ENSCPOP00000019473	Empty spiracles homeobox 1.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.499
KCNQ2	KCNQ3	ENSCPOP00000025733	ENSCPOP00000008115	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	0.990
KCNQ2	KCNQ5	ENSCPOP00000025733	ENSCPOP00000000106	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily Q member 5.	0.962
KCNQ2	PVALB	ENSCPOP00000025733	ENSCPOP00000019473	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.528
KCNQ2	SCN1A	ENSCPOP00000025733	ENSCPOP00000002422	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.605
KCNQ3	KCNQ2	ENSCPOP00000008115	ENSCPOP00000025733	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	0.990
KCNQ3	KCNQ5	ENSCPOP00000008115	ENSCPOP00000000106	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily Q member 5.	0.971
KCNQ3	PVALB	ENSCPOP00000008115	ENSCPOP00000019473	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.460
KCNQ3	SCN1A	ENSCPOP00000008115	ENSCPOP00000002422	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.431
KCNQ5	KCNQ2	ENSCPOP00000000106	ENSCPOP00000025733	Potassium voltage-gated channel subfamily Q member 5.	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	0.962
KCNQ5	KCNQ3	ENSCPOP00000000106	ENSCPOP00000008115	Potassium voltage-gated channel subfamily Q member 5.	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	0.971
KCNQ5	PVALB	ENSCPOP00000000106	ENSCPOP00000019473	Potassium voltage-gated channel subfamily Q member 5.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.513
PVALB	EMX1	ENSCPOP00000019473	ENSCPOP00000032459	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	Empty spiracles homeobox 1.	0.499
PVALB	KCNQ2	ENSCPOP00000019473	ENSCPOP00000025733	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	0.528
PVALB	KCNQ3	ENSCPOP00000019473	ENSCPOP00000008115	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	0.460
PVALB	KCNQ5	ENSCPOP00000019473	ENSCPOP00000000106	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	Potassium voltage-gated channel subfamily Q member 5.	0.513
PVALB	SCN1A	ENSCPOP00000019473	ENSCPOP00000002422	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.630
PVALB	SST	ENSCPOP00000019473	ENSCPOP00000008673	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	Somatostatin.	0.830
SCN1A	KCNQ2	ENSCPOP00000002422	ENSCPOP00000025733	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.	0.605
SCN1A	KCNQ3	ENSCPOP00000002422	ENSCPOP00000008115	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.	0.431