9 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mutyh	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (530 aa)
	PVALB	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity). (110 aa)
	NES	Nestin; Belongs to the intermediate filament family. (1712 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	NEIL2	Nei like DNA glycosylase 2. (336 aa)
	GABRA1	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	OGG1	8-oxoguanine DNA glycosylase. (303 aa)
	POLB	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (340 aa)
	NEIL1	Nei like DNA glycosylase 1. (401 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GABRA1	GABRA5	ENSCPOP00000006195	ENSCPOP00000003757	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.778
GABRA5	GABRA1	ENSCPOP00000003757	ENSCPOP00000006195	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.778
Mutyh	NEIL1	ENSCPOP00000011204	ENSCPOP00000009702	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Nei like DNA glycosylase 1.	0.623
Mutyh	NEIL2	ENSCPOP00000011204	ENSCPOP00000005469	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	Nei like DNA glycosylase 2.	0.553
Mutyh	OGG1	ENSCPOP00000011204	ENSCPOP00000007880	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	8-oxoguanine DNA glycosylase.	0.608
Mutyh	POLB	ENSCPOP00000011204	ENSCPOP00000009487	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.469
NEIL1	Mutyh	ENSCPOP00000009702	ENSCPOP00000011204	Nei like DNA glycosylase 1.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.623
NEIL1	NEIL2	ENSCPOP00000009702	ENSCPOP00000005469	Nei like DNA glycosylase 1.	Nei like DNA glycosylase 2.	0.876
NEIL1	OGG1	ENSCPOP00000009702	ENSCPOP00000007880	Nei like DNA glycosylase 1.	8-oxoguanine DNA glycosylase.	0.831
NEIL1	POLB	ENSCPOP00000009702	ENSCPOP00000009487	Nei like DNA glycosylase 1.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.890
NEIL2	Mutyh	ENSCPOP00000005469	ENSCPOP00000011204	Nei like DNA glycosylase 2.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.553
NEIL2	NEIL1	ENSCPOP00000005469	ENSCPOP00000009702	Nei like DNA glycosylase 2.	Nei like DNA glycosylase 1.	0.876
NEIL2	OGG1	ENSCPOP00000005469	ENSCPOP00000007880	Nei like DNA glycosylase 2.	8-oxoguanine DNA glycosylase.	0.762
NEIL2	POLB	ENSCPOP00000005469	ENSCPOP00000009487	Nei like DNA glycosylase 2.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.786
NES	PVALB	ENSCPOP00000026301	ENSCPOP00000019473	Nestin; Belongs to the intermediate filament family.	Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).	0.717
OGG1	Mutyh	ENSCPOP00000007880	ENSCPOP00000011204	8-oxoguanine DNA glycosylase.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.608
OGG1	NEIL1	ENSCPOP00000007880	ENSCPOP00000009702	8-oxoguanine DNA glycosylase.	Nei like DNA glycosylase 1.	0.831
OGG1	NEIL2	ENSCPOP00000007880	ENSCPOP00000005469	8-oxoguanine DNA glycosylase.	Nei like DNA glycosylase 2.	0.762
OGG1	POLB	ENSCPOP00000007880	ENSCPOP00000009487	8-oxoguanine DNA glycosylase.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.579
POLB	Mutyh	ENSCPOP00000009487	ENSCPOP00000011204	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.469