STRINGSTRING
SCN2A SCN2A DNASE1L2 DNASE1L2 PRICKLE2 PRICKLE2 DNASE1L1 DNASE1L1 ISL1 ISL1 DNASE1L3 DNASE1L3 Map2 Map2 TPM3 TPM3 TRIM46 TRIM46 NFASC NFASC PRICKLE1 PRICKLE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
PRICKLE2Prickle planar cell polarity protein 2. (901 aa)
DNASE1L1Deoxyribonuclease; Belongs to the DNase I family. (307 aa)
ISL1ISL LIM homeobox 1. (349 aa)
DNASE1L3Deoxyribonuclease; Belongs to the DNase I family. (302 aa)
Map2Microtubule-associated protein. (559 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)
TRIM46Tripartite motif containing 46. (672 aa)
NFASCNeurofascin. (1346 aa)
PRICKLE1Prickle planar cell polarity protein 1. (832 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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