13 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (738 aa)
	FGA	Fibrinogen alpha chain. (775 aa)
	NTRK1	Tyrosine-protein kinase receptor. (798 aa)
	SLC1A6	Amino acid transporter. (560 aa)
	SLC1A5	Amino acid transporter. (471 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	SLC1A2	Amino acid transporter. (573 aa)
	ALK	Tyrosine-protein kinase receptor. (1350 aa)
	SLC1A7	Amino acid transporter. (574 aa)
	SLC1A1	Amino acid transporter. (525 aa)
	CYTB	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (882 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CYTB	ENSCPOP00000022236	ENSCPOP00000014220	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.421
ALK	LGR5	ENSCPOP00000007403	ENSCPOP00000027425	Tyrosine-protein kinase receptor.	Leucine rich repeat containing G protein-coupled receptor 5.	0.473
CYTB	ACTB	ENSCPOP00000014220	ENSCPOP00000022236	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.421
LGR5	ALK	ENSCPOP00000027425	ENSCPOP00000007403	Leucine rich repeat containing G protein-coupled receptor 5.	Tyrosine-protein kinase receptor.	0.473
SLC1A1	SLC1A2	ENSCPOP00000011633	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.712
SLC1A1	SLC1A3	ENSCPOP00000011633	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.916
SLC1A1	SLC1A6	ENSCPOP00000011633	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.919
SLC1A1	SLC1A7	ENSCPOP00000011633	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.912
SLC1A2	SLC1A1	ENSCPOP00000007025	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.712
SLC1A2	SLC1A3	ENSCPOP00000007025	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.794
SLC1A2	SLC1A6	ENSCPOP00000007025	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.715
SLC1A2	SLC1A7	ENSCPOP00000007025	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.799
SLC1A3	SLC1A1	ENSCPOP00000006730	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.916
SLC1A3	SLC1A2	ENSCPOP00000006730	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.794
SLC1A3	SLC1A6	ENSCPOP00000006730	ENSCPOP00000001896	Amino acid transporter.	Amino acid transporter.	0.910
SLC1A3	SLC1A7	ENSCPOP00000006730	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.911
SLC1A6	SLC1A1	ENSCPOP00000001896	ENSCPOP00000011633	Amino acid transporter.	Amino acid transporter.	0.919
SLC1A6	SLC1A2	ENSCPOP00000001896	ENSCPOP00000007025	Amino acid transporter.	Amino acid transporter.	0.715
SLC1A6	SLC1A3	ENSCPOP00000001896	ENSCPOP00000006730	Amino acid transporter.	Amino acid transporter.	0.910
SLC1A6	SLC1A7	ENSCPOP00000001896	ENSCPOP00000009609	Amino acid transporter.	Amino acid transporter.	0.912