STRINGSTRING
SUSD2 SUSD2 VTN VTN FGF2 FGF2 HMBS HMBS CDX2 CDX2 GATA3 GATA3 GATA2 GATA2 TFCP2L1 TFCP2L1 TFAP2C TFAP2C Gdf3 Gdf3 Pou5f1 Pou5f1 DUSP6 DUSP6 ESRRB ESRRB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SUSD2Sushi domain containing 2. (823 aa)
VTNSMB domain-containing protein. (482 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (114 aa)
HMBSHydroxymethylbilane synthase. (361 aa)
CDX2Caudal type homeobox 2. (314 aa)
GATA3GATA binding protein 3. (443 aa)
GATA2GATA binding protein 2. (374 aa)
TFCP2L1Transcription factor CP2 like 1. (704 aa)
TFAP2CTranscription factor AP-2 gamma. (473 aa)
Gdf3TGF_BETA_2 domain-containing protein. (359 aa)
Pou5f1POU domain protein. (361 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
ESRRBEstrogen related receptor beta. (454 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.