31 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

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protein homology

Your Input:
	Casp3	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (165 aa)
	UCHL5	Ubiquitin carboxyl-terminal hydrolase. (324 aa)
	LOC100723623	Annexin. (327 aa)
	ANXA7	Annexin. (456 aa)
	Gpx5	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (224 aa)
	Alb	Preproalbumin. (608 aa)
	Glud1	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (540 aa)
	Anxa2	Annexin. (339 aa)
	GPX3	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
	GOT1	Aspartate aminotransferase. (413 aa)
	OGG1	8-oxoguanine DNA glycosylase. (303 aa)
	UXT	Ubiquitously expressed prefoldin like chaperone. (157 aa)
	ANXA13	Annexin. (315 aa)
	Cd4	Uncharacterized protein. (523 aa)
	ANXA3	Annexin. (323 aa)
	Brca1	Uncharacterized protein. (79 aa)
	ANXA1	Annexin. (346 aa)
	RPS9	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	ANXA11	Annexin. (499 aa)
	BCL2	BCL2 apoptosis regulator. (183 aa)
	ANXA6	Annexin. (753 aa)
	ANXA5	Annexin. (318 aa)
	XRCC5	X-ray repair cross complementing 5. (739 aa)
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (169 aa)
	ANXA4	Annexin. (321 aa)
	Gpx4	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (196 aa)
	GPX7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa)
	GPX8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
	ANXA9	Annexin. (345 aa)
	GOT2	Aspartate aminotransferase. (430 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	ANXA11	ENSCPOP00000013152	ENSCPOP00000016843	Annexin.	Annexin.	0.583
ANXA1	ANXA13	ENSCPOP00000013152	ENSCPOP00000008957	Annexin.	Annexin.	0.582
ANXA1	ANXA3	ENSCPOP00000013152	ENSCPOP00000011567	Annexin.	Annexin.	0.664
ANXA1	ANXA4	ENSCPOP00000013152	ENSCPOP00000026136	Annexin.	Annexin.	0.608
ANXA1	ANXA5	ENSCPOP00000013152	ENSCPOP00000022900	Annexin.	Annexin.	0.675
ANXA1	ANXA6	ENSCPOP00000013152	ENSCPOP00000021459	Annexin.	Annexin.	0.718
ANXA1	ANXA7	ENSCPOP00000013152	ENSCPOP00000002314	Annexin.	Annexin.	0.584
ANXA1	ANXA9	ENSCPOP00000013152	ENSCPOP00000032150	Annexin.	Annexin.	0.619
ANXA1	Anxa2	ENSCPOP00000013152	ENSCPOP00000005768	Annexin.	Annexin.	0.974
ANXA1	Casp3	ENSCPOP00000013152	ENSCPOP00000011256	Annexin.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.593
ANXA1	LOC100723623	ENSCPOP00000013152	ENSCPOP00000002296	Annexin.	Annexin.	0.606
ANXA1	TP53	ENSCPOP00000013152	ENSCPOP00000029751	Annexin.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.803
ANXA11	ANXA1	ENSCPOP00000016843	ENSCPOP00000013152	Annexin.	Annexin.	0.583
ANXA11	ANXA13	ENSCPOP00000016843	ENSCPOP00000008957	Annexin.	Annexin.	0.719
ANXA11	ANXA3	ENSCPOP00000016843	ENSCPOP00000011567	Annexin.	Annexin.	0.407
ANXA11	ANXA7	ENSCPOP00000016843	ENSCPOP00000002314	Annexin.	Annexin.	0.916
ANXA11	Anxa2	ENSCPOP00000016843	ENSCPOP00000005768	Annexin.	Annexin.	0.582
ANXA11	BCL2	ENSCPOP00000016843	ENSCPOP00000016923	Annexin.	BCL2 apoptosis regulator.	0.580
ANXA11	Casp3	ENSCPOP00000016843	ENSCPOP00000011256	Annexin.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.557
ANXA11	TP53	ENSCPOP00000016843	ENSCPOP00000029751	Annexin.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.517