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ERBB4 ERBB4 NRXN3 NRXN3 Gapdh Gapdh Vamp2 Vamp2 Camk2d Camk2d SYP SYP ACTB ACTB NEFL NEFL LRFN2 LRFN2 CTBP1 CTBP1 NLGN1 NLGN1 RPH3A RPH3A ABI1 ABI1 GPHN GPHN SCN3A SCN3A GABRA4 GABRA4 VPS54 VPS54 SLC1A2 SLC1A2 MAGI3 MAGI3 CAMK2A CAMK2A GABBR2 GABBR2 GABRB3 GABRB3 CDH4 CDH4 GABRA5 GABRA5 GABRD GABRD GRIA4 GRIA4 IGSF9B IGSF9B GRIK4 GRIK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERBB4Receptor protein-tyrosine kinase. (1263 aa)
NRXN3Neurexin 3. (1571 aa)
GapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (353 aa)
Vamp2V-SNARE coiled-coil homology domain-containing protein. (164 aa)
Camk2dProtein kinase domain-containing protein. (532 aa)
SYPSynaptophysin. (312 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (545 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (791 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (346 aa)
NLGN1Neuroligin 1. (843 aa)
RPH3ARabphilin 3A. (667 aa)
ABI1Abl interactor 1. (474 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (709 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
VPS54VPS54 subunit of GARP complex. (807 aa)
SLC1A2Amino acid transporter. (573 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1394 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (820 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (895 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (819 aa)
IGSF9BImmunoglobulin superfamily member 9B. (1369 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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