STRINGSTRING
ACTN3 ACTN3 PARVG PARVG Aspm Aspm IQGAP2 IQGAP2 GAS2L1 GAS2L1 TAGLN2 TAGLN2 PLEC PLEC TAGLN3 TAGLN3 IQGAP3 IQGAP3 Specc1l Specc1l ACTN4 ACTN4 CNN2 CNN2 SMTN SMTN SYNE2 SYNE2 CNN3 CNN3 TAGLN TAGLN LOC106027361 LOC106027361 MICAL2 MICAL2 LRCH3 LRCH3 MICALL2 MICALL2 FLNA FLNA ENSCPOP00000027603 ENSCPOP00000027603 ACTN1 ACTN1 PARVA PARVA FLNC FLNC SPTBN1 SPTBN1 GAS2 GAS2 SPECC1 SPECC1 SMTNL1 SMTNL1 Ehbp1l1 Ehbp1l1 PLS1 PLS1 LRCH2 LRCH2 GAS2L3 GAS2L3 FLNB FLNB ARHGEF6 ARHGEF6 LIMCH1 LIMCH1 CNN1 CNN1 SPTBN4 SPTBN4 DMD DMD DIXDC1 DIXDC1 PLS3 PLS3 LRCH4 LRCH4 DST DST CLMN CLMN MICAL1 MICAL1 SPTB SPTB EHBP1 EHBP1 LCP1 LCP1 MICALL1 MICALL1 UTRN UTRN MACF1 MACF1 LRCH1 LRCH1 Mical3 Mical3 SPTBN2 SPTBN2 ACTN2 ACTN2 IQGAP1 IQGAP1 PARVB PARVB SMTNL2 SMTNL2 NAV2 NAV2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTN3Actinin alpha 3 (gene/pseudogene). (889 aa)
PARVGParvin gamma. (223 aa)
AspmUncharacterized protein. (1053 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
GAS2L1Growth arrest specific 2 like 1. (675 aa)
TAGLN2Transgelin; Belongs to the calponin family. (199 aa)
PLECPlectin. (4689 aa)
TAGLN3Transgelin; Belongs to the calponin family. (199 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1663 aa)
Specc1lCalponin-homology (CH) domain-containing protein. (1129 aa)
ACTN4Actinin alpha 4. (911 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (306 aa)
SMTNSmoothelin. (919 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6922 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (310 aa)
TAGLNTransgelin; Belongs to the calponin family. (201 aa)
LOC106027361Uncharacterized protein. (1433 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1099 aa)
LRCH3Leucine rich repeats and calponin homology domain containing 3. (796 aa)
MICALL2MICAL like 2. (975 aa)
FLNAFilamin A. (2645 aa)
ENSCPOP00000027603Calponin-homology (CH) domain-containing protein. (252 aa)
ACTN1Actinin alpha 1. (914 aa)
PARVAParvin alpha. (347 aa)
FLNCFilamin C. (2726 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
GAS2Growth arrest specific 2. (314 aa)
SPECC1Sperm antigen with calponin homology and coiled-coil domains 1. (1058 aa)
SMTNL1Smoothelin like 1. (503 aa)
Ehbp1l1Uncharacterized protein. (907 aa)
PLS1Plastin 1. (630 aa)
LRCH2Leucine rich repeats and calponin homology domain containing 2. (768 aa)
GAS2L3Growth arrest specific 2 like 3. (680 aa)
FLNBFilamin B. (2602 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (765 aa)
LIMCH1LIM and calponin homology domains 1. (1072 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (256 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2530 aa)
DMDDystrophin. (3613 aa)
DIXDC1DIX domain containing 1. (683 aa)
PLS3Plastin 3. (637 aa)
LRCH4Leucine rich repeats and calponin homology domain containing 4. (681 aa)
DSTDystonin. (5380 aa)
CLMNCalmin. (974 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1068 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2358 aa)
EHBP1EH domain binding protein 1. (1176 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
MICALL1MICAL like 1. (846 aa)
UTRNUtrophin. (3432 aa)
MACF1Microtubule actin crosslinking factor 1. (7286 aa)
LRCH1Leucine rich repeats and calponin homology domain containing 1. (642 aa)
Mical3Calponin-homology (CH) domain-containing protein. (685 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2386 aa)
ACTN2Actinin alpha 2. (894 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1603 aa)
PARVBParvin beta. (365 aa)
SMTNL2Smoothelin like 2. (438 aa)
NAV2Neuron navigator 2. (2385 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.