17 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNAT1	Alpha-transducin. (350 aa)
	Gnat2	Uncharacterized protein. (354 aa)
	Gna15	Uncharacterized protein. (205 aa)
	GNAL	G protein subunit alpha L. (372 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	GNAT3	G protein subunit alpha transducin 3. (354 aa)
	GNA11	G protein subunit alpha 11. (345 aa)
	GNAZ	G protein subunit alpha z. (355 aa)
	ENSCPOP00000023932	Uncharacterized protein. (332 aa)
	GNAO1	G protein subunit alpha o1. (318 aa)
	GNAI2	Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa)
	GNAQ	G protein subunit alpha q. (313 aa)
	GNAI1	Uncharacterized protein. (330 aa)
	LOC100732436	Uncharacterized protein. (327 aa)
	GNA12	G protein subunit alpha 12. (315 aa)
	GNA14	G protein subunit alpha 14. (356 aa)
	GNAI3	Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCPOP00000023932	GNA11	ENSCPOP00000023932	ENSCPOP00000021515	Uncharacterized protein.	G protein subunit alpha 11.	0.456
ENSCPOP00000023932	GNA14	ENSCPOP00000023932	ENSCPOP00000004849	Uncharacterized protein.	G protein subunit alpha 14.	0.453
ENSCPOP00000023932	GNAI1	ENSCPOP00000023932	ENSCPOP00000030063	Uncharacterized protein.	Uncharacterized protein.	0.555
ENSCPOP00000023932	GNAI2	ENSCPOP00000023932	ENSCPOP00000025341	Uncharacterized protein.	Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily.	0.550
ENSCPOP00000023932	GNAI3	ENSCPOP00000023932	ENSCPOP00000010346	Uncharacterized protein.	Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...]	0.553
ENSCPOP00000023932	GNAL	ENSCPOP00000023932	ENSCPOP00000002727	Uncharacterized protein.	G protein subunit alpha L.	0.646
ENSCPOP00000023932	GNAO1	ENSCPOP00000023932	ENSCPOP00000024931	Uncharacterized protein.	G protein subunit alpha o1.	0.629
ENSCPOP00000023932	GNAQ	ENSCPOP00000023932	ENSCPOP00000026700	Uncharacterized protein.	G protein subunit alpha q.	0.451
ENSCPOP00000023932	GNAT1	ENSCPOP00000023932	ENSCPOP00000007345	Uncharacterized protein.	Alpha-transducin.	0.882
ENSCPOP00000023932	GNAT3	ENSCPOP00000023932	ENSCPOP00000014659	Uncharacterized protein.	G protein subunit alpha transducin 3.	0.631
ENSCPOP00000023932	Gna15	ENSCPOP00000023932	ENSCPOP00000004478	Uncharacterized protein.	Uncharacterized protein.	0.439
ENSCPOP00000023932	LOC100732436	ENSCPOP00000023932	ENSCPOP00000031430	Uncharacterized protein.	Uncharacterized protein.	0.602
GNA11	ENSCPOP00000023932	ENSCPOP00000021515	ENSCPOP00000023932	G protein subunit alpha 11.	Uncharacterized protein.	0.456
GNA11	GNA12	ENSCPOP00000021515	ENSCPOP00000001605	G protein subunit alpha 11.	G protein subunit alpha 12.	0.486
GNA11	GNA13	ENSCPOP00000021515	ENSCPOP00000011766	G protein subunit alpha 11.	G protein subunit alpha 13.	0.550
GNA11	GNAI1	ENSCPOP00000021515	ENSCPOP00000030063	G protein subunit alpha 11.	Uncharacterized protein.	0.499
GNA11	GNAI2	ENSCPOP00000021515	ENSCPOP00000025341	G protein subunit alpha 11.	Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily.	0.530
GNA11	GNAI3	ENSCPOP00000021515	ENSCPOP00000010346	G protein subunit alpha 11.	Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...]	0.530
GNA11	GNAO1	ENSCPOP00000021515	ENSCPOP00000024931	G protein subunit alpha 11.	G protein subunit alpha o1.	0.757
GNA11	GNAQ	ENSCPOP00000021515	ENSCPOP00000026700	G protein subunit alpha 11.	G protein subunit alpha q.	0.910