(45 nodes) Domain with 2 conserved Trp (W) residues network (Cavia porcellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARHGAP27	Rho GTPase activating protein 27. (796 aa)
	SAV1	Salvador family WW domain containing protein 1. (384 aa)
	YAP1	Yes associated protein 1. (397 aa)
	MAGI1	Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1181 aa)
	ARHGAP12	Rho GTPase activating protein 12. (842 aa)
	APBB3	Amyloid beta precursor protein binding family B member 3. (486 aa)
	APBB2	Amyloid beta precursor protein binding family B member 2. (761 aa)
	MAGI3	Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1394 aa)
	BAG3	BCL2 associated athanogene 3. (572 aa)
	SETD2	SET domain containing 2, histone lysine methyltransferase. (2565 aa)
	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1566 aa)
	DMD	Dystrophin. (3613 aa)
	WWOX	WW domain containing oxidoreductase. (414 aa)
	TCERG1L	Transcription elongation regulator 1 like. (579 aa)
	UTRN	Utrophin. (3432 aa)
	NEDD4	E3 ubiquitin-protein ligase. (896 aa)
	DRP2	Dystrophin related protein 2. (957 aa)
	FNBP4	Formin binding protein 4. (1044 aa)
	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1579 aa)
	PCIF1	PDX1 C-terminal inhibiting factor 1. (704 aa)
	SMURF1	E3 ubiquitin-protein ligase. (757 aa)
	CMTR1	Cap methyltransferase 1. (836 aa)
	STXBP4	Syntaxin binding protein 4. (558 aa)
	WWC1	WW and C2 domain containing 1. (1107 aa)
	ITCH	E3 ubiquitin-protein ligase. (862 aa)
	WBP4	WW domain binding protein 4. (378 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1603 aa)
	WWP1	E3 ubiquitin-protein ligase. (912 aa)
	MAGI2	Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1237 aa)
	ARHGAP39	Rho GTPase activating protein 39. (1114 aa)
	APBB1	Amyloid beta precursor protein binding family B member 1. (709 aa)
	PQBP1	Polyglutamine binding protein 1. (265 aa)
	PRPF40A	Pre-mRNA processing factor 40 homolog A. (960 aa)
	PRPF40B	Pre-mRNA processing factor 40 homolog B. (890 aa)
	WWTR1	WW domain containing transcription regulator 1. (400 aa)
	GAS7	Growth arrest specific 7. (425 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (992 aa)
	PLEKHA5	Pleckstrin homology domain containing A5. (1260 aa)
	SMURF2	E3 ubiquitin-protein ligase. (782 aa)
	WAC	WW domain containing adaptor with coiled-coil. (632 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (166 aa)
	WWP2	E3 ubiquitin-protein ligase. (870 aa)
	DGCR8	DGCR8 microprocessor complex subunit. (773 aa)
	TCERG1	Transcription elongation regulator 1. (1076 aa)
	WWC2	WW and C2 domain containing 2. (1151 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBB1	APBB2	ENSCPOP00000014979	ENSCPOP00000006026	Amyloid beta precursor protein binding family B member 1.	Amyloid beta precursor protein binding family B member 2.	0.687
APBB2	APBB1	ENSCPOP00000006026	ENSCPOP00000014979	Amyloid beta precursor protein binding family B member 2.	Amyloid beta precursor protein binding family B member 1.	0.687
ARHGAP12	GAS7	ENSCPOP00000005274	ENSCPOP00000023806	Rho GTPase activating protein 12.	Growth arrest specific 7.	0.430
ARHGAP12	IQGAP1	ENSCPOP00000005274	ENSCPOP00000012599	Rho GTPase activating protein 12.	IQ motif containing GTPase activating protein 1.	0.557
ARHGAP27	GAS7	ENSCPOP00000030843	ENSCPOP00000023806	Rho GTPase activating protein 27.	Growth arrest specific 7.	0.430
ARHGAP27	IQGAP1	ENSCPOP00000030843	ENSCPOP00000012599	Rho GTPase activating protein 27.	IQ motif containing GTPase activating protein 1.	0.557
ARHGAP39	GAS7	ENSCPOP00000013965	ENSCPOP00000023806	Rho GTPase activating protein 39.	Growth arrest specific 7.	0.418
BAG3	IQGAP1	ENSCPOP00000006809	ENSCPOP00000012599	BCL2 associated athanogene 3.	IQ motif containing GTPase activating protein 1.	0.402
BAG3	PRPF40A	ENSCPOP00000006809	ENSCPOP00000021988	BCL2 associated athanogene 3.	Pre-mRNA processing factor 40 homolog A.	0.516
BAG3	SAV1	ENSCPOP00000006809	ENSCPOP00000029394	BCL2 associated athanogene 3.	Salvador family WW domain containing protein 1.	0.617
BAG3	WWTR1	ENSCPOP00000006809	ENSCPOP00000023234	BCL2 associated athanogene 3.	WW domain containing transcription regulator 1.	0.407
DMD	UTRN	ENSCPOP00000008169	ENSCPOP00000000752	Dystrophin.	Utrophin.	0.861
DRP2	UTRN	ENSCPOP00000000477	ENSCPOP00000000752	Dystrophin related protein 2.	Utrophin.	0.464
FNBP4	PRPF40A	ENSCPOP00000000278	ENSCPOP00000021988	Formin binding protein 4.	Pre-mRNA processing factor 40 homolog A.	0.510
FNBP4	TCERG1	ENSCPOP00000000278	ENSCPOP00000002756	Formin binding protein 4.	Transcription elongation regulator 1.	0.493
FNBP4	WBP4	ENSCPOP00000000278	ENSCPOP00000012489	Formin binding protein 4.	WW domain binding protein 4.	0.552
GAS7	ARHGAP12	ENSCPOP00000023806	ENSCPOP00000005274	Growth arrest specific 7.	Rho GTPase activating protein 12.	0.430
GAS7	ARHGAP27	ENSCPOP00000023806	ENSCPOP00000030843	Growth arrest specific 7.	Rho GTPase activating protein 27.	0.430
GAS7	ARHGAP39	ENSCPOP00000023806	ENSCPOP00000013965	Growth arrest specific 7.	Rho GTPase activating protein 39.	0.418
GAS7	IQGAP1	ENSCPOP00000023806	ENSCPOP00000012599	Growth arrest specific 7.	IQ motif containing GTPase activating protein 1.	0.758