(29 nodes) A domain family that is part of the cupin metalloenzyme superfamily. network (Cavia porcellus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JMJD8	Jumonji domain containing 8. (268 aa)
	RIOX1	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (567 aa)
	KDM3B	Lysine demethylase 3B. (1723 aa)
	JMJD6	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
	KDM2B	Lysine demethylase 2B. (1306 aa)
	PHF8	PHD finger protein 8. (1021 aa)
	KDM4B	Lysine demethylase 4B. (1100 aa)
	RIOX2	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (464 aa)
	TYW5	tRNA-yW synthesizing protein 5. (315 aa)
	KDM3A	Lysine demethylase 3A. (1258 aa)
	KDM7A	Lysine demethylase 7A. (877 aa)
	JARID2	Jumonji and AT-rich interaction domain containing 2. (1247 aa)
	KDM5A	Lysine demethylase 5A. (1527 aa)
	JMJD1C	Jumonji domain containing 1C. (2536 aa)
	KDM6A	Lysine demethylase 6A. (1164 aa)
	JMJD4	Jumonji domain containing 4. (425 aa)
	LOC100721657	Uncharacterized protein. (854 aa)
	PHF2	PHD finger protein 2. (1066 aa)
	HSPBAP1	HSPB1 associated protein 1. (471 aa)
	KDM8	Lysine demethylase 8. (416 aa)
	HR	HR lysine demethylase and nuclear receptor corepressor. (1208 aa)
	KDM6B	Lysine demethylase 6B. (1467 aa)
	KDM4C	Lysine demethylase 4C. (1054 aa)
	KDM4D	Lysine demethylase 4D. (512 aa)
	KDM2A	Lysine demethylase 2A. (1161 aa)
	KDM5C	Lysine demethylase 5C. (1251 aa)
	HIF1AN	Hypoxia inducible factor 1 subunit alpha inhibitor. (334 aa)
	Kdm4a	Uncharacterized protein. (978 aa)
	KDM5B	Lysine demethylase 5B. (1529 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HR	KDM2A	ENSCPOP00000002974	ENSCPOP00000006433	HR lysine demethylase and nuclear receptor corepressor.	Lysine demethylase 2A.	0.421
HR	KDM2B	ENSCPOP00000002974	ENSCPOP00000027446	HR lysine demethylase and nuclear receptor corepressor.	Lysine demethylase 2B.	0.421
HSPBAP1	JMJD4	ENSCPOP00000000066	ENSCPOP00000013100	HSPB1 associated protein 1.	Jumonji domain containing 4.	0.555
HSPBAP1	KDM3B	ENSCPOP00000000066	ENSCPOP00000028277	HSPB1 associated protein 1.	Lysine demethylase 3B.	0.461
HSPBAP1	RIOX1	ENSCPOP00000000066	ENSCPOP00000032777	HSPB1 associated protein 1.	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.	0.553
HSPBAP1	RIOX2	ENSCPOP00000000066	ENSCPOP00000022510	HSPB1 associated protein 1.	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.	0.436
JARID2	KDM2A	ENSCPOP00000011943	ENSCPOP00000006433	Jumonji and AT-rich interaction domain containing 2.	Lysine demethylase 2A.	0.417
JARID2	KDM2B	ENSCPOP00000011943	ENSCPOP00000027446	Jumonji and AT-rich interaction domain containing 2.	Lysine demethylase 2B.	0.685
JARID2	KDM6B	ENSCPOP00000011943	ENSCPOP00000003983	Jumonji and AT-rich interaction domain containing 2.	Lysine demethylase 6B.	0.405
JMJD1C	KDM2A	ENSCPOP00000012777	ENSCPOP00000006433	Jumonji domain containing 1C.	Lysine demethylase 2A.	0.410
JMJD1C	KDM2B	ENSCPOP00000012777	ENSCPOP00000027446	Jumonji domain containing 1C.	Lysine demethylase 2B.	0.410
JMJD1C	KDM4B	ENSCPOP00000012777	ENSCPOP00000022727	Jumonji domain containing 1C.	Lysine demethylase 4B.	0.570
JMJD1C	KDM4C	ENSCPOP00000012777	ENSCPOP00000004232	Jumonji domain containing 1C.	Lysine demethylase 4C.	0.541
JMJD1C	KDM7A	ENSCPOP00000012777	ENSCPOP00000010087	Jumonji domain containing 1C.	Lysine demethylase 7A.	0.658
JMJD4	HSPBAP1	ENSCPOP00000013100	ENSCPOP00000000066	Jumonji domain containing 4.	HSPB1 associated protein 1.	0.555
JMJD4	KDM8	ENSCPOP00000013100	ENSCPOP00000002073	Jumonji domain containing 4.	Lysine demethylase 8.	0.553
JMJD4	RIOX1	ENSCPOP00000013100	ENSCPOP00000032777	Jumonji domain containing 4.	Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.	0.553
JMJD6	KDM3A	ENSCPOP00000028254	ENSCPOP00000020827	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.	Lysine demethylase 3A.	0.487
JMJD6	KDM4C	ENSCPOP00000028254	ENSCPOP00000004232	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.	Lysine demethylase 4C.	0.454
JMJD6	KDM5A	ENSCPOP00000028254	ENSCPOP00000012388	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.	Lysine demethylase 5A.	0.599