node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAT1 | ACAT2 | ENSCPOP00000013564 | ENSCPOP00000001508 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.933 |
ACAT1 | BDH1 | ENSCPOP00000013564 | ENSCPOP00000030175 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.577 |
ACAT1 | BDH2 | ENSCPOP00000013564 | ENSCPOP00000023284 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyrate dehydrogenase 2. | 0.607 |
ACAT1 | HMGCL | ENSCPOP00000013564 | ENSCPOP00000007766 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.954 |
ACAT1 | HMGCLL1 | ENSCPOP00000013564 | ENSCPOP00000005600 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.847 |
ACAT1 | HMGCS1 | ENSCPOP00000013564 | ENSCPOP00000023141 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.992 |
ACAT1 | HMGCS2 | ENSCPOP00000013564 | ENSCPOP00000005713 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.993 |
ACAT1 | OXCT1 | ENSCPOP00000013564 | ENSCPOP00000021409 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.930 |
ACAT1 | OXCT2 | ENSCPOP00000013564 | ENSCPOP00000018408 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.930 |
ACAT2 | ACAT1 | ENSCPOP00000001508 | ENSCPOP00000013564 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.933 |
ACAT2 | BDH2 | ENSCPOP00000001508 | ENSCPOP00000023284 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyrate dehydrogenase 2. | 0.607 |
ACAT2 | HMGCL | ENSCPOP00000001508 | ENSCPOP00000007766 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.947 |
ACAT2 | HMGCLL1 | ENSCPOP00000001508 | ENSCPOP00000005600 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.824 |
ACAT2 | HMGCS1 | ENSCPOP00000001508 | ENSCPOP00000023141 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.993 |
ACAT2 | HMGCS2 | ENSCPOP00000001508 | ENSCPOP00000005713 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.991 |
ACAT2 | OXCT1 | ENSCPOP00000001508 | ENSCPOP00000021409 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.921 |
ACAT2 | OXCT2 | ENSCPOP00000001508 | ENSCPOP00000018408 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.921 |
BDH1 | ACAT1 | ENSCPOP00000030175 | ENSCPOP00000013564 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.577 |
BDH1 | BDH2 | ENSCPOP00000030175 | ENSCPOP00000023284 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxybutyrate dehydrogenase 2. | 0.940 |
BDH1 | HMGCL | ENSCPOP00000030175 | ENSCPOP00000007766 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.933 |