STRINGSTRING
SPSB2 SPSB2 QTRT2 QTRT2 ENTPD7 ENTPD7 DHODH DHODH Cln8 Cln8 ENSCPOP00000032249 ENSCPOP00000032249 SLC25A42 SLC25A42 FBXO45 FBXO45 PNP PNP TMEM116 TMEM116 ENSCPOP00000033036 ENSCPOP00000033036 DPYS DPYS SLC12A1 SLC12A1 KDM1B KDM1B NME1 NME1 MRPS34 MRPS34 UCKL1 UCKL1 NT5E NT5E GPR143 GPR143 UMPS UMPS NME5 NME5 Nudt4 Nudt4 RRM2 RRM2 CMPK2 CMPK2 TLCD4 TLCD4 TTLL1 TTLL1 UPP2 UPP2 CTPS1 CTPS1 ENTPD1 ENTPD1 DPYD DPYD TTC5 TTC5 NT5DC1 NT5DC1 ENTPD6 ENTPD6 ENTPD5 ENTPD5 ENTPD4 ENTPD4 ENTPD8 ENTPD8 CC2D2A CC2D2A CALB2 CALB2 CANT1 CANT1 SVOPL SVOPL FBXO41 FBXO41 HDDC2 HDDC2 CEP44 CEP44 RRM1 RRM1 NT5C3A NT5C3A FBXL2 FBXL2 SVOP SVOP FBXL20 FBXL20 ENPP1 ENPP1 TYMS TYMS NT5C2 NT5C2 NT5C3B NT5C3B NT5M NT5M TTLL10 TTLL10 SPSB3 SPSB3 DTYMK DTYMK NME2 NME2 QTRT1 QTRT1 LOC100734586 LOC100734586 ENTPD3 ENTPD3 LOC100721923 LOC100721923 DUT DUT TYMP TYMP UPP1 UPP1 UCK1 UCK1 SPSB1 SPSB1 CDADC1 CDADC1 CTPS2 CTPS2 DCTD DCTD CEP97 CEP97 UCK2 UCK2 GOLT1B GOLT1B LOC100730882 LOC100730882 CENPW CENPW TTL TTL UPRT UPRT DCTPP1 DCTPP1 NUDT2 NUDT2 NT5C1A NT5C1A CAD CAD NUDT3 NUDT3 TK2 TK2 OLA1 OLA1 UPB1 UPB1 GOLT1A GOLT1A TLCD3B TLCD3B NME7 NME7 TLCD3A TLCD3A DCK DCK NME6 NME6 NME4 NME4 NT5C NT5C CMPK1 CMPK1 RRM2B RRM2B NME3 NME3 LOC100715002 LOC100715002 RIDA RIDA PPP1R8 PPP1R8 SPSB4 SPSB4 TK1 TK1 Ttll5 Ttll5 IPO9 IPO9 SHISA4 SHISA4 CDA CDA ENPP3 ENPP3 CFAP54 CFAP54
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPSB2SplA/ryanodine receptor domain and SOCS box containing 2. (211 aa)
QTRT2Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (415 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
DHODHDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
Cln8CLN8 transmembrane ER and ERGIC protein. (288 aa)
ENSCPOP00000032249Uncharacterized protein. (564 aa)
SLC25A42Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
FBXO45F-box protein 45. (283 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (288 aa)
TMEM116Transmembrane protein 116. (327 aa)
ENSCPOP00000033036Uncharacterized protein; Belongs to the GroES chaperonin family. (85 aa)
DPYSDihydropyrimidinase. (512 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
KDM1BLysine demethylase 1B. (831 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
MRPS34Mitochondrial ribosomal protein S34. (218 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (548 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (564 aa)
GPR143G protein-coupled receptor 143. (407 aa)
UMPSUridine monophosphate synthetase. (480 aa)
NME5NME/NM23 family member 5; Belongs to the NDK family. (211 aa)
Nudt4Nudix hydrolase domain-containing protein. (147 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (389 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (446 aa)
TLCD4TLC domain containing 4. (263 aa)
TTLL1Tubulin tyrosine ligase like 1. (423 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (320 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (511 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
TTC5Tetratricopeptide repeat domain 5. (445 aa)
NT5DC15'-nucleotidase domain containing 1. (451 aa)
ENTPD6Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (445 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (434 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (617 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (493 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1623 aa)
CALB2Calbindin 2. (271 aa)
CANT1Calcium activated nucleotidase 1. (433 aa)
SVOPLSVOP like. (465 aa)
FBXO41F-box protein 41. (875 aa)
HDDC2HD domain containing 2. (199 aa)
CEP44Centrosomal protein 44. (347 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (798 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
FBXL2F-box and leucine rich repeat protein 2. (430 aa)
SVOPSV2 related protein. (561 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (900 aa)
TYMSThymidylate synthetase. (314 aa)
NT5C25'-nucleotidase, cytosolic II. (564 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (337 aa)
NT5M5',3'-nucleotidase, mitochondrial. (206 aa)
TTLL10Tubulin tyrosine ligase like 10. (496 aa)
SPSB3SplA/ryanodine receptor domain and SOCS box containing 3. (388 aa)
DTYMKDeoxythymidylate kinase. (212 aa)
NME2Nucleoside diphosphate kinase. (152 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (404 aa)
LOC100734586Nudix hydrolase domain-containing protein. (170 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (530 aa)
LOC100721923Nudix hydrolase domain-containing protein. (164 aa)
DUTDeoxyuridine triphosphatase. (163 aa)
TYMPThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (479 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (311 aa)
UCK1Uridine-cytidine kinase 1. (232 aa)
SPSB1SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa)
CDADC1Cytidine and dCMP deaminase domain containing 1. (524 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
DCTDdCMP deaminase. (184 aa)
CEP97Centrosomal protein 97. (832 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
GOLT1BGolgi transport 1B. (138 aa)
LOC100730882Uncharacterized protein. (249 aa)
CENPWCentromere protein W. (88 aa)
TTLTubulin tyrosine ligase. (376 aa)
UPRTUracil phosphoribosyltransferase homolog. (309 aa)
DCTPP1dCTP pyrophosphatase 1. (184 aa)
NUDT2Nudix hydrolase 2. (147 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (364 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2248 aa)
NUDT3Nudix hydrolase 3. (162 aa)
TK2Thymidine kinase 2. (264 aa)
OLA1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (396 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
GOLT1AGolgi transport 1A. (127 aa)
TLCD3BTLC domain containing 3B. (275 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa)
TLCD3ATLC domain containing 3A. (257 aa)
DCKDeoxycytidine kinase. (260 aa)
NME6NME/NM23 nucleoside diphosphate kinase 6; Belongs to the NDK family. (155 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
NT5C5', 3'-nucleotidase, cytosolic. (205 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (227 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (351 aa)
NME3NME/NM23 nucleoside diphosphate kinase 3. (148 aa)
LOC100715002Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
RIDAReactive intermediate imine deaminase A homolog. (137 aa)
PPP1R8Protein phosphatase 1 regulatory subunit 8. (357 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
TK1Thymidine kinase. (233 aa)
Ttll5Uncharacterized protein. (1324 aa)
IPO9Importin 9. (1034 aa)
SHISA4Shisa family member 4. (192 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (145 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (772 aa)
CFAP54Cilia and flagella associated protein 54. (3110 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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