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PLPPR4 PLPPR4 ARHGEF39 ARHGEF39 DGKK DGKK GLA GLA AKR1B1 AKR1B1 ACAD10 ACAD10 TRMT1L TRMT1L PLPPR5 PLPPR5 CEL CEL TMC1 TMC1 ALDH16A1 ALDH16A1 PNLIPRP2 PNLIPRP2 LIPC LIPC LPL LPL DGAT2 DGAT2 GK5 GK5 SEC23IP SEC23IP SHROOM4 SHROOM4 DGAT1 DGAT1 PLPPR2 PLPPR2 PNPLA2 PNPLA2 MBOAT2 MBOAT2 MN1 MN1 LOC100723118 LOC100723118 PITPNM3 PITPNM3 AGPAT3 AGPAT3 Btbd10 Btbd10 MOGAT2 MOGAT2 PITPNB PITPNB DGKG DGKG DGKQ DGKQ FGGY FGGY PLPPR1 PLPPR1 LIPI LIPI PUDP PUDP PITPNA PITPNA TMEM64 TMEM64 LPIN2 LPIN2 PLPPR3 PLPPR3 PINX1 PINX1 Aldh2 Aldh2 DGKE DGKE GLYCTK GLYCTK TMEM41B TMEM41B PITPNM2 PITPNM2 KCTD20 KCTD20 ALDH7A1 ALDH7A1 Gk Gk AGPAT1 AGPAT1 DGKZ DGKZ LCLAT1 LCLAT1 AGPAT4 AGPAT4 DDHD1 DDHD1 AKR1E2 AKR1E2 MGLL MGLL AKR1A1 AKR1A1 PLPP4 PLPP4 TRMT1 TRMT1 PITPNC1 PITPNC1 PITPNM1 PITPNM1 H0VGL3_CAVPO H0VGL3_CAVPO TCTN2 TCTN2 TKFC TKFC DGKA DGKA CCDC115 CCDC115 Plpp1 Plpp1 DGKD DGKD PNPLA5 PNPLA5 LIPG LIPG MBOAT1 MBOAT1 GPAT2 GPAT2 LIPK LIPK LIPF LIPF HEXIM1 HEXIM1 AGPAT5 AGPAT5 DGKH DGKH ALDH9A1 ALDH9A1 GPAT3 GPAT3 DDHD2 DDHD2 Rmdn1 Rmdn1 CENPF CENPF RMDN3 RMDN3 LIPH LIPH H0VPC1_CAVPO H0VPC1_CAVPO MOGAT1 MOGAT1 LPIN1 LPIN1 PNLIP PNLIP AGK AGK GPAM GPAM LPIN3 LPIN3 LOC100714895 LOC100714895 PLPP5 PLPP5 H0VWD9_CAVPO H0VWD9_CAVPO H0VXS2_CAVPO H0VXS2_CAVPO LOC100725498 LOC100725498 PNPLA3 PNPLA3 PLPP2 PLPP2 Rmdn2 Rmdn2 H0WBQ2_CAVPO H0WBQ2_CAVPO AGPAT2 AGPAT2 Plpp3 Plpp3 GPAT4 GPAT4 DGKI DGKI ALDH3A2 ALDH3A2 TMEM41A TMEM41A MED23 MED23 TTLL12 TTLL12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLPPR4Phospholipid phosphatase related 4. (748 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (331 aa)
DGKKDiacylglycerol kinase. (1062 aa)
GLAAlpha-galactosidase. (428 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1059 aa)
TRMT1LtRNA methyltransferase 1 like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (722 aa)
PLPPR5Phospholipid phosphatase related 5. (315 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (594 aa)
TMC1Transmembrane channel-like protein. (761 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (804 aa)
PNLIPRP2Pancreatic lipase-related protein 2; Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. (451 aa)
LIPCLipase C, hepatic type. (497 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (495 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
GK5Glycerol kinase 5; Belongs to the FGGY kinase family. (524 aa)
SEC23IPSEC23 interacting protein. (994 aa)
SHROOM4Shroom family member 4. (1534 aa)
DGAT1O-acyltransferase. (493 aa)
PLPPR2Phospholipid phosphatase related 2. (420 aa)
PNPLA2Patatin like phospholipase domain containing 2. (486 aa)
MBOAT2Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family. (537 aa)
MN1MN1 proto-oncogene, transcriptional regulator. (1320 aa)
LOC100723118Aldo_ket_red domain-containing protein. (316 aa)
PITPNM3PITPNM family member 3. (1015 aa)
AGPAT31-acylglycerol-3-phosphate O-acyltransferase 3. (376 aa)
Btbd10BTB domain-containing protein. (482 aa)
MOGAT2Monoacylglycerol O-acyltransferase 2. (305 aa)
PITPNBPhosphatidylinositol transfer protein beta. (272 aa)
DGKGDiacylglycerol kinase. (792 aa)
DGKQDiacylglycerol kinase. (947 aa)
FGGYFGGY carbohydrate kinase domain containing. (552 aa)
PLPPR1Phospholipid phosphatase related 1. (325 aa)
LIPILipase I. (474 aa)
PUDPPseudouridine 5'-phosphatase. (235 aa)
PITPNAPhosphatidylinositol transfer protein alpha. (271 aa)
TMEM64Transmembrane protein 64. (376 aa)
LPIN2Lipin 2. (915 aa)
PLPPR3Phospholipid phosphatase related 3. (775 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (325 aa)
Aldh2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa)
DGKEDiacylglycerol kinase. (575 aa)
GLYCTKGlycerate kinase. (521 aa)
TMEM41BTransmembrane protein 41B. (276 aa)
PITPNM2Phosphatidylinositol transfer protein membrane associated 2. (1332 aa)
KCTD20Potassium channel tetramerization domain containing 20. (419 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (539 aa)
GkUncharacterized protein; Belongs to the FGGY kinase family. (559 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (284 aa)
DGKZDiacylglycerol kinase. (1118 aa)
LCLAT1Lysocardiolipin acyltransferase 1. (376 aa)
AGPAT41-acylglycerol-3-phosphate O-acyltransferase 4. (378 aa)
DDHD1DDHD domain containing 1. (826 aa)
AKR1E2Aldo-keto reductase family 1 member E2. (330 aa)
MGLLMonoglyceride lipase. (314 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (325 aa)
PLPP4Phospholipid phosphatase 4. (270 aa)
TRMT1tRNA (guanine(26)-N(2))-dimethyltransferase. (660 aa)
PITPNC1Phosphatidylinositol transfer protein cytoplasmic 1. (308 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1244 aa)
H0VGL3_CAVPOASD2 domain-containing protein. (446 aa)
TCTN2Tectonic family member 2. (703 aa)
TKFCTriokinase and FMN cyclase. (578 aa)
DGKADiacylglycerol kinase. (736 aa)
CCDC115Coiled-coil domain containing 115. (179 aa)
Plpp1Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1- phosphate/C1P. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these b [...] (284 aa)
DGKDDiacylglycerol kinase. (1160 aa)
PNPLA5Patatin like phospholipase domain containing 5. (384 aa)
LIPGLipase G, endothelial type. (498 aa)
MBOAT1Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (463 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (795 aa)
LIPKLipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
LIPFLipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
HEXIM1Uncharacterized protein. (218 aa)
AGPAT51-acylglycerol-3-phosphate O-acyltransferase 5. (338 aa)
DGKHDiacylglycerol kinase. (1144 aa)
ALDH9A1Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (518 aa)
GPAT3Glycerol-3-phosphate acyltransferase 3. (437 aa)
DDHD2DDHD domain containing 2. (668 aa)
Rmdn1Uncharacterized protein. (300 aa)
CENPFCentromere protein F. (3022 aa)
RMDN3Regulator of microtubule dynamics 3. (463 aa)
LIPHLipase H. (497 aa)
H0VPC1_CAVPOG-patch domain-containing protein. (119 aa)
MOGAT1Monoacylglycerol O-acyltransferase 1. (303 aa)
LPIN1Lipin 1. (899 aa)
PNLIPPancreatic triacylglycerol lipase. (428 aa)
AGKAcylglycerol kinase. (421 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
LPIN3Lipin 3. (821 aa)
LOC100714895Uncharacterized protein. (421 aa)
PLPP5Phospholipid phosphatase 5. (244 aa)
H0VWD9_CAVPOBTB_3 domain-containing protein. (420 aa)
H0VXS2_CAVPOUncharacterized protein. (282 aa)
LOC100725498Aldo_ket_red domain-containing protein. (315 aa)
PNPLA3Patatin like phospholipase domain containing 3. (405 aa)
PLPP2Phospholipid phosphatase 2. (260 aa)
Rmdn2Uncharacterized protein. (419 aa)
H0WBQ2_CAVPOUncharacterized protein. (282 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (278 aa)
Plpp3acidPPc domain-containing protein. (312 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
DGKIDiacylglycerol kinase. (957 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
TMEM41ATransmembrane protein 41A. (264 aa)
MED23Mediator complex subunit 23. (1377 aa)
TTLL12Tubulin tyrosine ligase like 12. (639 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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