28 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	HMGCL	3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
	BDH1	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
	ACSM1	Acyl-CoA synthetase medium chain family member 1. (524 aa)
	ALDH5A1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (472 aa)
	EHHADH	Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	BDH2	3-hydroxybutyrate dehydrogenase 2. (245 aa)
	HMGCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
	OXCT1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
	CARTPT	CART prepropeptide. (129 aa)
	OXCT2	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (503 aa)
	ACSM4	Acyl-CoA synthetase medium chain family member 4. (578 aa)
	HADH	Hydroxyacyl-CoA dehydrogenase. (313 aa)
	ACADS	Acyl-CoA dehydrogenase short chain. (413 aa)
	ACAT1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
	GAD2	Glutamate decarboxylase 2. (585 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	L2HGDH	L-2-hydroxyglutarate dehydrogenase. (463 aa)
	ACSM3	Acyl-CoA synthetase medium chain family member 3. (585 aa)
	AACS	Acetoacetyl-CoA synthetase. (672 aa)
	LOC100732696	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	HMGCLL1	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (307 aa)
	HADHA	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
	GAD1	Glutamate decarboxylase 1. (594 aa)
	ACSM5	Acyl-CoA synthetase medium chain family member 5. (579 aa)
	LOC100730233	Uncharacterized protein. (577 aa)
	ACAT2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AACS	ABAT	ENSCPOP00000006716	ENSCPOP00000025444	Acetoacetyl-CoA synthetase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.556
AACS	ACADS	ENSCPOP00000006716	ENSCPOP00000013906	Acetoacetyl-CoA synthetase.	Acyl-CoA dehydrogenase short chain.	0.633
AACS	ACAT1	ENSCPOP00000006716	ENSCPOP00000013564	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.896
AACS	ACAT2	ENSCPOP00000006716	ENSCPOP00000001508	Acetoacetyl-CoA synthetase.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.869
AACS	ALDH5A1	ENSCPOP00000006716	ENSCPOP00000026312	Acetoacetyl-CoA synthetase.	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.745
AACS	BDH1	ENSCPOP00000006716	ENSCPOP00000030175	Acetoacetyl-CoA synthetase.	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.817
AACS	BDH2	ENSCPOP00000006716	ENSCPOP00000023284	Acetoacetyl-CoA synthetase.	3-hydroxybutyrate dehydrogenase 2.	0.817
AACS	CARTPT	ENSCPOP00000006716	ENSCPOP00000021136	Acetoacetyl-CoA synthetase.	CART prepropeptide.	0.798
AACS	ECHS1	ENSCPOP00000006716	ENSCPOP00000010906	Acetoacetyl-CoA synthetase.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.636
AACS	EHHADH	ENSCPOP00000006716	ENSCPOP00000025721	Acetoacetyl-CoA synthetase.	Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.768
AACS	HADH	ENSCPOP00000006716	ENSCPOP00000015742	Acetoacetyl-CoA synthetase.	Hydroxyacyl-CoA dehydrogenase.	0.870
AACS	HADHA	ENSCPOP00000006716	ENSCPOP00000005365	Acetoacetyl-CoA synthetase.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.	0.646
AACS	HMGCL	ENSCPOP00000006716	ENSCPOP00000007766	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.815
AACS	HMGCLL1	ENSCPOP00000006716	ENSCPOP00000005600	Acetoacetyl-CoA synthetase.	3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.	0.817
AACS	HMGCS1	ENSCPOP00000006716	ENSCPOP00000023141	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.907
AACS	HMGCS2	ENSCPOP00000006716	ENSCPOP00000005713	Acetoacetyl-CoA synthetase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.849
AACS	LOC100732696	ENSCPOP00000006716	ENSCPOP00000006672	Acetoacetyl-CoA synthetase.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.768
AACS	OXCT1	ENSCPOP00000006716	ENSCPOP00000021409	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.751
AACS	OXCT2	ENSCPOP00000006716	ENSCPOP00000018408	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.751
ABAT	AACS	ENSCPOP00000025444	ENSCPOP00000006716	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Acetoacetyl-CoA synthetase.	0.556