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MOCS1 MOCS1 LOC100723118 LOC100723118 MFSD9 MFSD9 LIN7C LIN7C MOCOS MOCOS LOC100724677 LOC100724677 CATSPER3 CATSPER3 TH TH GPHN GPHN MOCS2 MOCS2 FPGS FPGS LOC100724954 LOC100724954 LOC100725498 LOC100725498 SPR SPR SLC30A9 SLC30A9 TPH1 TPH1 GFM1 GFM1 AKR1B1 AKR1B1 LIN7A LIN7A TRMT1L TRMT1L FAM193B FAM193B LIN7B LIN7B GCH1 GCH1 TPH2 TPH2 ALPL ALPL H0W440_CAVPO H0W440_CAVPO CCDC166 CCDC166 PRELID1 PRELID1 LOC100723593 LOC100723593 PCBD1 PCBD1 AKR1E2 AKR1E2 PRELID3A PRELID3A Dhfr Dhfr DDX41 DDX41 PCBD2 PCBD2 PRELID3B PRELID3B GGH GGH PAH PAH QDPR QDPR NIF3L1 NIF3L1 LOC100723873 LOC100723873 C2orf69 C2orf69 PTS PTS TRMT1 TRMT1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MOCS1Molybdenum cofactor synthesis 1. (636 aa)
LOC100723118Aldo_ket_red domain-containing protein. (316 aa)
MFSD9Major facilitator superfamily domain containing 9. (464 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (873 aa)
LOC100724677Alkaline phosphatase. (527 aa)
CATSPER3Cation channel sperm associated 3. (380 aa)
THTyrosine hydroxylase. (498 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (709 aa)
MOCS2Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. (173 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (582 aa)
LOC100724954Uncharacterized protein; Belongs to the alkaline phosphatase family. (540 aa)
LOC100725498Aldo_ket_red domain-containing protein. (315 aa)
SPRSepiapterin reductase. (262 aa)
SLC30A9Solute carrier family 30 member 9. (542 aa)
TPH1Tryptophan hydroxylase 1. (420 aa)
GFM1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (754 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (205 aa)
TRMT1LtRNA methyltransferase 1 like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (722 aa)
FAM193BFamily with sequence similarity 193 member B. (780 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
GCH1GTP cyclohydrolase 1. (222 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
ALPLAlkaline phosphatase. (524 aa)
H0W440_CAVPOUncharacterized protein. (140 aa)
CCDC166Coiled-coil domain containing 166. (439 aa)
PRELID1PRELI domain containing 1. (219 aa)
LOC100723593Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa)
AKR1E2Aldo-keto reductase family 1 member E2. (330 aa)
PRELID3APRELI domain containing 3A. (172 aa)
DhfrDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
DDX41DEAD-box helicase 41. (622 aa)
PCBD2Pterin-4 alpha-carbinolamine dehydratase 2. (102 aa)
PRELID3BPRELI domain containing 3B. (194 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
PAHPhenylalanine hydroxylase. (452 aa)
QDPRQuinoid dihydropteridine reductase. (242 aa)
NIF3L1NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. (376 aa)
LOC100723873Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (278 aa)
C2orf69Chromosome 2 open reading frame 69. (366 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
TRMT1tRNA (guanine(26)-N(2))-dimethyltransferase. (660 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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