STRINGSTRING
REXO1 REXO1 GNL3 GNL3 BMS1 BMS1 FCF1 FCF1 BRD4 BRD4 UTP18 UTP18 C15orf40 C15orf40 TUBGCP4 TUBGCP4 BRD3 BRD3 GNL1 GNL1 ZNF622 ZNF622 RETREG1 RETREG1 H0UYX0_CAVPO H0UYX0_CAVPO TCOF1 TCOF1 RETREG3 RETREG3 POP1 POP1 POP4 POP4 Xrn1 Xrn1 VWC2 VWC2 H0V1T7_CAVPO H0V1T7_CAVPO SPATA5 SPATA5 Csnk2a1 Csnk2a1 POP7 POP7 NMD3 NMD3 UTP4 UTP4 TBL3 TBL3 TMEM223 TMEM223 NXF1 NXF1 TMEM120A TMEM120A RBM28 RBM28 ARHGAP42 ARHGAP42 ARHGAP26 ARHGAP26 HEATR1 HEATR1 SPATA5L1 SPATA5L1 CSNK2A2 CSNK2A2 NXT1 NXT1 DKC1 DKC1 REXO5 REXO5 XRN2 XRN2 RIOK1 RIOK1 KRI1 KRI1 REXO2 REXO2 RIOK2 RIOK2 CSNK2B CSNK2B WDR43 WDR43 ADGRD1 ADGRD1 NOL6 NOL6 POP5 POP5 MCC MCC WDR75 WDR75 MPHOSPH10 MPHOSPH10 GTPBP4 GTPBP4 Utp14a Utp14a UTP6 UTP6 DROSHA DROSHA DXO DXO NOP56 NOP56 RCL1 RCL1 GNL3L GNL3L MDN1 MDN1 RPP38 RPP38 Pwp2 Pwp2 EMG1 EMG1 LOC100716734 LOC100716734 FBLL1 FBLL1 NOB1 NOB1 IMP4 IMP4 AK6 AK6 GNL2 GNL2 IMP3 IMP3 Trub1 Trub1 EFL1 EFL1 TMEM203 TMEM203 LOC100732818 LOC100732818 NOP58 NOP58 RRP7A RRP7A RPP25L RPP25L XPO1 XPO1 UTP15 UTP15 NVL NVL BRD2 BRD2 NOP10 NOP10 ENSCPOP00000023532 ENSCPOP00000023532 FBL FBL WDR36 WDR36 WDR3 WDR3 METTL9 METTL9 SNU13 SNU13 RPP40 RPP40 CPTP CPTP GAR1 GAR1 ENSCPOP00000027661 ENSCPOP00000027661 Ly6g5b Ly6g5b ENSCPOP00000027781 ENSCPOP00000027781 EIF6 EIF6 ENSCPOP00000027965 ENSCPOP00000027965 NHP2 NHP2 SBDS SBDS ENSCPOP00000028553 ENSCPOP00000028553 RPP30 RPP30 Nxt2 Nxt2 RETREG2 RETREG2 TMEM167B TMEM167B NAT10 NAT10 TMEM167A TMEM167A OPHN1 OPHN1 GLTPD2 GLTPD2 TMEM120B TMEM120B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
REXO1RNA exonuclease 1 homolog. (1231 aa)
GNL3G protein nucleolar 3. (518 aa)
BMS1BMS1 ribosome biogenesis factor. (1277 aa)
FCF1PINc domain-containing protein. (198 aa)
BRD4Bromodomain containing 4. (1373 aa)
UTP18UTP18 small subunit processome component. (540 aa)
C15orf40Chromosome 15 open reading frame 40. (126 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (666 aa)
BRD3Bromodomain containing 3. (725 aa)
GNL1G protein nucleolar 1 (putative). (608 aa)
ZNF622Zinc finger protein 622. (478 aa)
RETREG1Reticulophagy regulator 1. (413 aa)
H0UYX0_CAVPOUncharacterized protein. (174 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1601 aa)
RETREG3Reticulophagy regulator family member 3. (466 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1012 aa)
POP4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (220 aa)
Xrn15'-3' exoribonuclease 1. (1386 aa)
VWC2Von Willebrand factor C domain containing 2. (315 aa)
H0V1T7_CAVPOUncharacterized protein. (269 aa)
SPATA5Spermatogenesis associated 5. (884 aa)
Csnk2a1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (465 aa)
UTP4UTP4 small subunit processome component. (686 aa)
TBL3Transducin beta like 3. (800 aa)
TMEM223Transmembrane protein 223. (196 aa)
NXF1Nuclear RNA export factor 1. (618 aa)
TMEM120ATransmembrane protein 120A. (343 aa)
RBM28RNA binding motif protein 28. (758 aa)
ARHGAP42Rho GTPase activating protein 42. (832 aa)
ARHGAP26Rho GTPase activating protein 26. (759 aa)
HEATR1HEAT repeat containing 1. (2142 aa)
SPATA5L1Spermatogenesis associated 5 like 1; Belongs to the AAA ATPase family. (634 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (349 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
DKC1Dyskerin pseudouridine synthase 1. (513 aa)
REXO5RNA exonuclease 5. (814 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
RIOK1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (570 aa)
KRI1KRI1 homolog. (693 aa)
REXO2RNA exonuclease 2. (237 aa)
RIOK2RIO kinase 2. (548 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (244 aa)
WDR43WD repeat domain 43. (654 aa)
ADGRD1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (881 aa)
NOL6Nucleolar protein 6. (1146 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (168 aa)
MCCMCC regulator of WNT signaling pathway. (1009 aa)
WDR75WD repeat domain 75. (848 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (681 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
Utp14aUncharacterized protein. (697 aa)
UTP6UTP6 small subunit processome component. (596 aa)
DROSHADrosha ribonuclease III. (1295 aa)
DXODecapping exoribonuclease. (397 aa)
NOP56NOP56 ribonucleoprotein. (592 aa)
RCL1RNA terminal phosphate cyclase like 1. (373 aa)
GNL3LG protein nucleolar 3 like. (574 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5563 aa)
RPP38Ribonuclease P/MRP subunit p38. (284 aa)
Pwp2Uncharacterized protein. (924 aa)
EMG1EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
LOC100716734NTF2 domain-containing protein. (644 aa)
FBLL1Fibrillarin like 1. (307 aa)
NOB1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (409 aa)
IMP4IMP U3 small nucleolar ribonucleoprotein 4. (210 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (708 aa)
IMP3IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
Trub1TruB_N domain-containing protein. (244 aa)
EFL1Elongation factor like GTPase 1. (1126 aa)
TMEM203Transmembrane protein 203. (136 aa)
LOC100732818Uncharacterized protein. (773 aa)
NOP58NOP58 ribonucleoprotein. (512 aa)
RRP7ARibosomal RNA processing 7 homolog A. (280 aa)
RPP25LRibonuclease P/MRP subunit p25 like. (163 aa)
XPO1Exportin 1. (1062 aa)
UTP15UTP15 small subunit processome component. (517 aa)
NVLNuclear VCP like. (849 aa)
BRD2Bromodomain containing 2. (804 aa)
NOP10NOP10 ribonucleoprotein. (64 aa)
ENSCPOP00000023532XRN_N domain-containing protein. (103 aa)
FBLFibrillarin. (320 aa)
WDR36WD repeat domain 36. (909 aa)
WDR3WD repeat domain 3. (943 aa)
METTL9Methyltransferase like 9. (318 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
RPP40Ribonuclease P/MRP subunit p40. (363 aa)
CPTPCeramide-1-phosphate transfer protein. (214 aa)
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (222 aa)
ENSCPOP00000027661Uncharacterized protein. (177 aa)
Ly6g5bUncharacterized protein. (195 aa)
ENSCPOP00000027781TruB_N domain-containing protein. (257 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (246 aa)
ENSCPOP00000027965Bromo domain-containing protein. (321 aa)
NHP2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
ENSCPOP00000028553Fcf2 domain-containing protein. (109 aa)
RPP30Ribonuclease P/MRP subunit p30. (268 aa)
Nxt2NTF2 domain-containing protein. (114 aa)
RETREG2Reticulophagy regulator family member 2. (544 aa)
TMEM167BProtein kish; Involved in the early part of the secretory pathway. (74 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1030 aa)
TMEM167AProtein kish; Involved in the early part of the secretory pathway. Belongs to the KISH family. (72 aa)
OPHN1Uncharacterized protein. (802 aa)
GLTPD2GLTP domain-containing protein. (196 aa)
TMEM120BTransmembrane protein 120B. (339 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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