STRINGSTRING
RFC3 RFC3 Fbxw12 Fbxw12 H0W9J0_CAVPO H0W9J0_CAVPO POLD2 POLD2 RFC5 RFC5 CETN1 CETN1 H0VSL9_CAVPO H0VSL9_CAVPO H0VSI3_CAVPO H0VSI3_CAVPO CDK7 CDK7 MNAT1 MNAT1 H0VPN0_CAVPO H0VPN0_CAVPO POLE POLE DDB2 DDB2 RFC2 RFC2 Cetn2 Cetn2 ATAD5 ATAD5 Clspn Clspn RFC4 RFC4 FBH1 FBH1 GTF2H3 GTF2H3 PCNA PCNA H0VDH6_CAVPO H0VDH6_CAVPO GTF2H4 GTF2H4 POLD1 POLD1 POLE4 POLE4 ENSCPOP00000022087 ENSCPOP00000022087 Pold4 Pold4 POLE3 POLE3 Bivm Bivm CHRAC1 CHRAC1 CCNH CCNH RAD23B RAD23B ERCC2 ERCC2 RBX1 RBX1 CUL4B CUL4B LOC100732574 LOC100732574 STN1 STN1 LOC100717396 LOC100717396 GTF2H1 GTF2H1 RPA3 RPA3 DDB1 DDB1 RAD23A RAD23A PRKRIP1 PRKRIP1 GTF2H5 GTF2H5 ENSCPOP00000029727 ENSCPOP00000029727 ERCC1 ERCC1 ERCC6 ERCC6 RPA2 RPA2 YJU2 YJU2 CDK20 CDK20 Ppil3 Ppil3 CUL4A CUL4A ZNF608 ZNF608 Pold3 Pold3 XPC XPC H0V698_CAVPO H0V698_CAVPO Ercc8 Ercc8 ERCC4 ERCC4 POLE2 POLE2 RFC1 RFC1 Lig1 Lig1 DDX11 DDX11 WDR76 WDR76 ERCC3 ERCC3 ZNF609 ZNF609 XPA XPA MEIOB MEIOB ERCC5 ERCC5 CABP5 CABP5 RPA1 RPA1 SASS6 SASS6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC3Replication factor C subunit 3. (220 aa)
Fbxw12Uncharacterized protein. (469 aa)
H0W9J0_CAVPOUncharacterized protein. (147 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
RFC5Replication factor C subunit 5. (340 aa)
CETN1Centrin 1. (172 aa)
H0VSL9_CAVPOSsl1 domain-containing protein. (160 aa)
H0VSI3_CAVPODNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (677 aa)
CDK7Cyclin dependent kinase 7. (335 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
H0VPN0_CAVPOC1_4 domain-containing protein. (286 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa)
DDB2Damage specific DNA binding protein 2. (289 aa)
RFC2Replication factor C subunit 2. (352 aa)
Cetn2Uncharacterized protein. (172 aa)
ATAD5ATPase family AAA domain containing 5. (1831 aa)
ClspnUncharacterized protein. (1330 aa)
RFC4Replication factor C subunit 4. (363 aa)
FBH1F-box DNA helicase 1. (1012 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
H0VDH6_CAVPOVWFA domain-containing protein. (365 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (485 aa)
POLD1DNA polymerase. (1134 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (116 aa)
ENSCPOP00000022087Uncharacterized protein. (161 aa)
Pold4Uncharacterized protein. (107 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
BivmUncharacterized protein. (503 aa)
CHRAC1Chromatin accessibility complex subunit 1. (129 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
RBX1Ring-box 1. (108 aa)
CUL4BCullin 4B; Belongs to the cullin family. (936 aa)
LOC100732574General transcription factor IIH subunit. (395 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (375 aa)
LOC100717396Uncharacterized protein. (1249 aa)
GTF2H1General transcription factor IIH subunit 1. (556 aa)
RPA3Replication protein A3. (121 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (362 aa)
PRKRIP1PRKR interacting protein 1. (186 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ENSCPOP00000029727C1_4 domain-containing protein. (309 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (300 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1473 aa)
RPA2Replication protein A2. (270 aa)
YJU2YJU2 splicing factor homolog. (305 aa)
CDK20Cyclin dependent kinase 20; Belongs to the protein kinase superfamily. (346 aa)
Ppil3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
ZNF608Zinc finger protein 608. (1268 aa)
Pold3Uncharacterized protein. (466 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (923 aa)
H0V698_CAVPOC2H2-type domain-containing protein. (374 aa)
Ercc8WD_REPEATS_REGION domain-containing protein. (396 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
RFC1Replication factor C subunit 1. (1153 aa)
Lig1DNA ligase. (909 aa)
DDX11DEAD/H-box helicase 11. (878 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (623 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (781 aa)
ZNF609Zinc finger protein 609. (1409 aa)
XPAXPA, DNA damage recognition and repair factor. (263 aa)
MEIOBMeiosis specific with OB-fold. (471 aa)
ERCC5ERCC excision repair 5, endonuclease. (1059 aa)
CABP5Calcium binding protein 5. (173 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
SASS6SAS-6 centriolar assembly protein. (590 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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