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ENSCPOP00000029477 | Ig-like domain-containing protein. (137 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1214 aa) | ||||
MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (160 aa) | ||||
FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa) | ||||
TLN1 | Talin 1. (2537 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) | ||||
VAV3 | Vav guanine nucleotide exchange factor 3. (779 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa) | ||||
NGFR | Nerve growth factor receptor. (429 aa) | ||||
ADAM15 | ADAM metallopeptidase domain 15. (862 aa) | ||||
EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (230 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (269 aa) | ||||
CALM2 | Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa) | ||||
MAGI1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1181 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (194 aa) | ||||
ANGPT1 | Angiopoietin 1. (487 aa) | ||||
ADCY1 | Adenylate cyclase 1. (944 aa) | ||||
RAPGEF5 | Rap guanine nucleotide exchange factor 5. (811 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (865 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa) | ||||
FYB1 | FYN binding protein 1. (823 aa) | ||||
VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (348 aa) | ||||
RGS14 | Regulator of G protein signaling 14. (570 aa) | ||||
APBB1IP | Amyloid beta precursor protein binding family B member 1 interacting protein. (611 aa) | ||||
H0V3A7_CAVPO | Uncharacterized protein. (1320 aa) | ||||
H0V3F2_CAVPO | Uncharacterized protein. (1365 aa) | ||||
GPR55 | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (313 aa) | ||||
PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (845 aa) | ||||
Ralgds | Uncharacterized protein. (906 aa) | ||||
FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (114 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1367 aa) | ||||
PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) | ||||
ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa) | ||||
ACTL7A | Actin like 7A; Belongs to the actin family. (440 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) | ||||
GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1381 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (822 aa) | ||||
PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) | ||||
ITGA2B | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1007 aa) | ||||
CRK | CRK proto-oncogene, adaptor protein. (281 aa) | ||||
ENAH | ENAH actin regulator. (768 aa) | ||||
MAGI3 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1394 aa) | ||||
ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1170 aa) | ||||
ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) | ||||
FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1343 aa) | ||||
FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) | ||||
H0VE70_CAVPO | Uncharacterized protein. (796 aa) | ||||
DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa) | ||||
EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) | ||||
PFN4 | Profilin; Belongs to the profilin family. (129 aa) | ||||
PLCE1 | Phosphoinositide phospholipase C. (2282 aa) | ||||
H0VFH9_CAVPO | Fibrinogen C-terminal domain-containing protein. (480 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1029 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa) | ||||
VASP | Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (376 aa) | ||||
Rapgef6 | Uncharacterized protein. (1587 aa) | ||||
H0VH94_CAVPO | Ig-like domain-containing protein. (123 aa) | ||||
RAPGEF4 | Rap guanine nucleotide exchange factor 4. (989 aa) | ||||
FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (180 aa) | ||||
NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
PARD6A | Par-6 family cell polarity regulator alpha. (346 aa) | ||||
ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) | ||||
Itgb3 | Integrin beta; Belongs to the integrin beta chain family. (735 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa) | ||||
GNAI3 | Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa) | ||||
RPS6KL1 | Ribosomal protein S6 kinase like 1. (634 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) | ||||
CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (891 aa) | ||||
H0VKV0_CAVPO | Uncharacterized protein; Belongs to the calmodulin family. (139 aa) | ||||
PRKD3 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (889 aa) | ||||
ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1543 aa) | ||||
DOCK4 | Dedicator of cytokinesis 4; Belongs to the DOCK family. (1970 aa) | ||||
PDGFC | Platelet derived growth factor C. (295 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1371 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (325 aa) | ||||
FARP2 | FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1052 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1332 aa) | ||||
MET | MET proto-oncogene, receptor tyrosine kinase. (1380 aa) | ||||
GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1462 aa) | ||||
TIAM1 | T cell lymphoma invasion and metastasis 1. (1590 aa) | ||||
PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (593 aa) | ||||
RAC3 | Rac family small GTPase 3. (192 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) | ||||
RHOC | Ras homolog family member C. (193 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
THBS1 | Thrombospondin 1. (1163 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (367 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (572 aa) | ||||
MAGI2 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1237 aa) | ||||
AKT3 | AKT serine/threonine kinase 3. (470 aa) | ||||
PARD3 | Par-3 family cell polarity regulator. (1294 aa) | ||||
MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) | ||||
P2RY1 | P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. Belongs to the G-protein coupled receptor 1 family. (373 aa) | ||||
H0VUM6_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (552 aa) | ||||
PFN3 | Profilin; Belongs to the profilin family. (137 aa) | ||||
H0VVE5_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (528 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (979 aa) | ||||
RAC2 | Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa) | ||||
ITGB2 | Integrin beta. (767 aa) | ||||
ACTRT2 | Actin related protein T2; Belongs to the actin family. (376 aa) | ||||
H0VWH7_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. (441 aa) | ||||
H0VX85_CAVPO | Uncharacterized protein. (184 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (308 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa) | ||||
H0VXT9_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (546 aa) | ||||
H0VYG8_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. (327 aa) | ||||
H0W027_CAVPO | Uncharacterized protein. (722 aa) | ||||
H0W0B4_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (639 aa) | ||||
H0W0D3_CAVPO | Ig-like domain-containing protein. (126 aa) | ||||
H0W1P6_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (539 aa) | ||||
P2RY11 | Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (408 aa) | ||||
ACTL7B | Actin like 7B; Belongs to the actin family. (412 aa) | ||||
RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1263 aa) | ||||
ACTRT1 | Actin related protein T1; Belongs to the actin family. (377 aa) | ||||
EFNA2 | Ephrin A2; Belongs to the ephrin family. (190 aa) | ||||
H0W3Y7_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (503 aa) | ||||
LOC101787807 | Profilin; Belongs to the profilin family. (153 aa) | ||||
TLNRD1 | Talin rod domain containing 1. (355 aa) | ||||
H0W5D4_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. (455 aa) | ||||
LOC100725331 | Uncharacterized protein. (1433 aa) | ||||
LAT | Linker for activation of T cells. (236 aa) | ||||
LOC100731872 | Uncharacterized protein; Belongs to the actin family. (1226 aa) | ||||
H0W7V2_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (555 aa) | ||||
ACTL9 | Actin like 9; Belongs to the actin family. (388 aa) | ||||
ACTL8 | Actin like 8; Belongs to the actin family. (371 aa) | ||||
H0W9K9_CAVPO | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (539 aa) | ||||
CNR1 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa) | ||||
SKAP1 | Src kinase associated phosphoprotein 1. (365 aa) | ||||
NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI. (308 aa) | ||||
PARD6B | Par-6 family cell polarity regulator beta. (357 aa) | ||||
H0WD09_CAVPO | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (323 aa) | ||||
ADORA2A | Adenosine receptor A2a; Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). (409 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa) | ||||
LOC100732158 | Uncharacterized protein. (246 aa) | ||||
SIPA1L3 | Signal induced proliferation associated 1 like 3. (1774 aa) | ||||
ENSCPOP00000022108 | Uncharacterized protein; Belongs to the protein kinase superfamily. (348 aa) | ||||
ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1. (211 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
Csf1 | Uncharacterized protein. (257 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
ENSCPOP00000022761 | Uncharacterized protein; Belongs to the protein kinase superfamily. (451 aa) | ||||
CTNND1 | Catenin delta 1. (966 aa) | ||||
PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa) | ||||
TLN2 | Talin 2. (2542 aa) | ||||
LOC100713271 | Uncharacterized protein. (165 aa) | ||||
ANGPT2 | Angiopoietin 2. (494 aa) | ||||
ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (221 aa) | ||||
VAV2 | Vav guanine nucleotide exchange factor 2. (807 aa) | ||||
CALML4 | Calmodulin like 4. (153 aa) | ||||
LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa) | ||||
ENSCPOP00000024109 | DUF1968 domain-containing protein. (138 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (385 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa) | ||||
RASGRP2 | RAS guanyl releasing protein 2. (608 aa) | ||||
F2RL3 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (381 aa) | ||||
F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa) | ||||
RAPGEF3 | Rap guanine nucleotide exchange factor 3. (926 aa) | ||||
GNAO1 | G protein subunit alpha o1. (318 aa) | ||||
RALB | RAS like proto-oncogene B. (206 aa) | ||||
PARD6G | Par-6 family cell polarity regulator gamma. (382 aa) | ||||
GNAI2 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa) | ||||
ENSCPOP00000025438 | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (589 aa) | ||||
RGS12 | Regulator of G protein signaling 12. (1431 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa) | ||||
RAP1GAP | RAP1 GTPase activating protein. (744 aa) | ||||
ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) | ||||
ITGAM | Integrin alpha-M; Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated act [...] (1123 aa) | ||||
TRBV24-1 | T cell receptor beta variable 24-1. (133 aa) | ||||
MRAS | Muscle RAS oncogene homolog. (208 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
LCP2 | Lymphocyte cytosolic protein 2. (570 aa) | ||||
FGFR3 | Fibroblast growth factor receptor. (801 aa) | ||||
TRBV19 | T cell receptor beta variable 19. (129 aa) | ||||
RASGRP3 | RAS guanyl releasing protein 3. (691 aa) | ||||
GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (943 aa) | ||||
Vegfa | Vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa) | ||||
GNAQ | G protein subunit alpha q. (313 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
PGF | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (168 aa) | ||||
Rap1gap2 | RAP1 GTPase activating protein 2. (744 aa) | ||||
EVL | Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (420 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) | ||||
FGFR2 | Fibroblast growth factor receptor. (801 aa) | ||||
BCAR1 | BCAR1 scaffold protein, Cas family member. (879 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (271 aa) | ||||
ID1 | Inhibitor of DNA binding 1, HLH protein. (151 aa) | ||||
ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa) | ||||
ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) | ||||
CALM3 | Calmodulin 3. (149 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) | ||||
ENSCPOP00000027886 | Uncharacterized protein; Belongs to the protein kinase superfamily. (455 aa) | ||||
RALA | RAS like proto-oncogene A. (206 aa) | ||||
ENSCPOP00000028111 | Uncharacterized protein; Belongs to the protein kinase superfamily. (348 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
ENSCPOP00000028279 | Ig-like domain-containing protein. (134 aa) | ||||
ENSCPOP00000028355 | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (631 aa) | ||||
ENSCPOP00000028400 | Ig-like domain-containing protein. (116 aa) | ||||
AFDN | Afadin, adherens junction formation factor. (1794 aa) | ||||
EFNA1 | Ephrin A1; Belongs to the ephrin family. (166 aa) | ||||
RRAS | RAS related. (218 aa) | ||||
ENSCPOP00000028762 | Uncharacterized protein. (107 aa) | ||||
ENSCPOP00000029012 | Uncharacterized protein. (138 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) | ||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) | ||||
PFN2 | Profilin; Belongs to the profilin family. (140 aa) | ||||
PFN1 | Profilin; Belongs to the profilin family. (140 aa) | ||||
SIPA1 | Signal-induced proliferation-associated 1. (1040 aa) | ||||
VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (206 aa) | ||||
ENSCPOP00000029904 | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (633 aa) | ||||
GNAI1 | Uncharacterized protein. (330 aa) | ||||
LOC100734206 | Uncharacterized protein. (461 aa) | ||||
SIPA1L1 | Signal induced proliferation associated 1 like 1. (1803 aa) | ||||
ACTG1 | Actin gamma 1. (375 aa) | ||||
EPHA2 | EPH receptor A2. (976 aa) | ||||
EFNA4 | Ephrin A4; Belongs to the ephrin family. (204 aa) | ||||
LPAR2 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (348 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa) | ||||
Fgf9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (91 aa) | ||||
LPAR3 | Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
LOC100732436 | Uncharacterized protein. (327 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
CDC42 | Cell division cycle 42. (191 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (738 aa) | ||||
Krit1 | Uncharacterized protein. (736 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (801 aa) | ||||
ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) | ||||
Rapgef2 | Uncharacterized protein. (1640 aa) | ||||
CSDE1 | Cold shock domain-containing protein E1; RNA-binding protein. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity). (779 aa) | ||||
IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (153 aa) | ||||
GALK2 | Galactokinase 2. (458 aa) | ||||
RASSF5 | Ras association domain family member 5. (415 aa) | ||||
ENSCPOP00000032025 | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (631 aa) | ||||
ENSCPOP00000032059 | Uncharacterized protein; Belongs to the calmodulin family. (73 aa) | ||||
ENSCPOP00000032481 | Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (589 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (190 aa) | ||||
SIPA1L2 | Signal induced proliferation associated 1 like 2. (1720 aa) | ||||
Rap1b | Uncharacterized protein. (184 aa) | ||||
ENSCPOP00000032616 | Ig-like domain-containing protein. (125 aa) | ||||
CTNNB1 | Catenin beta 1. (781 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
PDGFD | Platelet derived growth factor D. (370 aa) | ||||
RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |