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TACR1 | Substance-P receptor; This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. (407 aa) | ||||
AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (418 aa) | ||||
ENSCPOP00000031130 | Ig-like domain-containing protein. (136 aa) | ||||
ADRA1A | Alpha-1A adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity). (466 aa) | ||||
MYLK2 | Myosin light chain kinase 2. (593 aa) | ||||
ENSCPOP00000031332 | Ig-like domain-containing protein. (138 aa) | ||||
LOC100732436 | Uncharacterized protein. (327 aa) | ||||
AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa) | ||||
ENSCPOP00000031748 | Ig-like domain-containing protein. (136 aa) | ||||
PPP3R1 | Uncharacterized protein. (169 aa) | ||||
LRRN4CL | LRRN4 C-terminal like. (226 aa) | ||||
ENSCPOP00000032059 | Uncharacterized protein; Belongs to the calmodulin family. (73 aa) | ||||
CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (408 aa) | ||||
CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2164 aa) | ||||
CASQ1 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (190 aa) | ||||
ENSCPOP00000032517 | Ig-like domain-containing protein. (129 aa) | ||||
ENSCPOP00000032616 | Ig-like domain-containing protein. (125 aa) | ||||
HTR2A | 5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (470 aa) | ||||
HRH2 | Histamine H2 receptor; The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (422 aa) | ||||
TBXA2R | Thromboxane A2 receptor. (347 aa) | ||||
Prkaca | Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa) | ||||
PDGFD | Platelet derived growth factor D. (370 aa) | ||||
ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) | ||||
CALM3 | Calmodulin 3. (149 aa) | ||||
RYR3 | Ryanodine receptor 3. (4843 aa) | ||||
ENSCPOP00000028279 | Ig-like domain-containing protein. (134 aa) | ||||
ENSCPOP00000028400 | Ig-like domain-containing protein. (116 aa) | ||||
Ltb4r2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (360 aa) | ||||
ENSCPOP00000028569 | ANF_receptor domain-containing protein. (260 aa) | ||||
Vdac1 | Uncharacterized protein. (283 aa) | ||||
PTAFR | Platelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. (342 aa) | ||||
OXTR | Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (390 aa) | ||||
ENSCPOP00000028990 | Ig-like domain-containing protein. (138 aa) | ||||
ENSCPOP00000029012 | Uncharacterized protein. (138 aa) | ||||
SLC8A3 | Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) | ||||
PTGFR | Prostaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (365 aa) | ||||
Chrna7 | Uncharacterized protein. (483 aa) | ||||
ENSCPOP00000029145 | Ig-like domain-containing protein. (136 aa) | ||||
ENSCPOP00000029147 | Uncharacterized protein. (272 aa) | ||||
P2RX1 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa) | ||||
PDE1C | Phosphodiesterase. (685 aa) | ||||
PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa) | ||||
ENSCPOP00000029468 | Ig-like domain-containing protein. (122 aa) | ||||
ENSCPOP00000029477 | Ig-like domain-containing protein. (137 aa) | ||||
ATP2C1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (977 aa) | ||||
OSBPL9 | Oxysterol-binding protein; Belongs to the OSBP family. (746 aa) | ||||
ENSCPOP00000029769 | Ig-like domain-containing protein. (139 aa) | ||||
ORAI2 | ORAI calcium release-activated calcium modulator 2. (307 aa) | ||||
HTR2C | 5-hydroxytryptamine receptor 2C. (458 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa) | ||||
Camk2d | Protein kinase domain-containing protein. (532 aa) | ||||
ATP2B3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1226 aa) | ||||
ENSCPOP00000030754 | Ig-like domain-containing protein. (139 aa) | ||||
ENSCPOP00000030758 | Ig-like domain-containing protein. (122 aa) | ||||
PDE1A | Phosphodiesterase. (531 aa) | ||||
NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1149 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1214 aa) | ||||
MYLK4 | Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (386 aa) | ||||
PHKG1 | Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (388 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity [...] (480 aa) | ||||
GRPR | Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa) | ||||
H0UU35_CAVPO | G_PROTEIN_RECEP_F1_2 domain-containing protein. (359 aa) | ||||
PLCD1 | Phosphoinositide phospholipase C. (755 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa) | ||||
TRDC | T cell receptor delta constant. (140 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (481 aa) | ||||
GRIN2C | Glutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1209 aa) | ||||
QRFPR | Pyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa) | ||||
CALM2 | Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa) | ||||
HTR6 | 5-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (437 aa) | ||||
SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa) | ||||
ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa) | ||||
CYSLTR1 | Cysteinyl leukotriene receptor 1; Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). (340 aa) | ||||
Mcub | MCU domain-containing protein. (195 aa) | ||||
PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa) | ||||
SLC8A1 | Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage- gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (970 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (194 aa) | ||||
TPCN2 | Two pore channel 2. (752 aa) | ||||
ADCY1 | Adenylate cyclase 1. (944 aa) | ||||
ITPKA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (434 aa) | ||||
GNAL | G protein subunit alpha L. (372 aa) | ||||
CHRM5 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (530 aa) | ||||
TNNC1 | Troponin C1, slow skeletal and cardiac type. (161 aa) | ||||
STIM2 | Stromal interaction molecule 2. (742 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa) | ||||
HRC | Histidine rich calcium binding protein. (674 aa) | ||||
H0V1A0_CAVPO | YccV-like domain-containing protein. (541 aa) | ||||
GRM1 | Glutamate metabotropic receptor 1. (1195 aa) | ||||
MYLK3 | Myosin light chain kinase 3. (811 aa) | ||||
P2rx4 | Uncharacterized protein. (343 aa) | ||||
CAMK1G | Calcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (478 aa) | ||||
NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity); Belongs to the NOS family. (1206 aa) | ||||
CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa) | ||||
EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa) | ||||
MYLK | Myosin light chain kinase. (1959 aa) | ||||
Gna15 | Uncharacterized protein. (205 aa) | ||||
SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
GNA14 | G protein subunit alpha 14. (356 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
TPCN1 | Two pore channel 1. (817 aa) | ||||
PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) | ||||
ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1256 aa) | ||||
STK33 | Serine/threonine kinase 33; Belongs to the protein kinase superfamily. (461 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) | ||||
TACR2 | Substance-K receptor; This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (402 aa) | ||||
H0V789_CAVPO | Ig-like domain-containing protein. (126 aa) | ||||
PHKB | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1075 aa) | ||||
CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa) | ||||
PLCZ1 | Phosphoinositide phospholipase C. (601 aa) | ||||
MCOLN2 | Mucolipin 2. (540 aa) | ||||
CCKAR | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (430 aa) | ||||
CAMK4 | Calcium/calmodulin dependent protein kinase IV. (418 aa) | ||||
PLCD3 | Phosphoinositide phospholipase C. (785 aa) | ||||
ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) | ||||
ASPH | Aspartate beta-hydroxylase. (644 aa) | ||||
ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa) | ||||
AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (359 aa) | ||||
ZRANB2 | Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family. (328 aa) | ||||
HTR5A | 5-hydroxytryptamine receptor 5A. (356 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (531 aa) | ||||
CAMK1 | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa) | ||||
GRM5 | Glutamate metabotropic receptor 5. (873 aa) | ||||
ITPKC | Kinase; Belongs to the inositol phosphokinase (IPK) family. (679 aa) | ||||
SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
H0VE70_CAVPO | Uncharacterized protein. (796 aa) | ||||
PLCE1 | Phosphoinositide phospholipase C. (2282 aa) | ||||
MCOLN1 | Mucolipin 1. (582 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (518 aa) | ||||
SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (840 aa) | ||||
VDAC3 | Voltage dependent anion channel 3. (283 aa) | ||||
H0VH94_CAVPO | Ig-like domain-containing protein. (123 aa) | ||||
ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1263 aa) | ||||
TRHR | Thyrotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (393 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) | ||||
CACNA1I | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2067 aa) | ||||
H0VKV0_CAVPO | Uncharacterized protein; Belongs to the calmodulin family. (139 aa) | ||||
SPHK1 | Sphingosine kinase 1. (386 aa) | ||||
CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2337 aa) | ||||
HTR4 | 5-hydroxytryptamine receptor 4; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity); Belongs to the G-protein coupled receptor 1 family. (388 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa) | ||||
PDGFC | Platelet derived growth factor C. (295 aa) | ||||
P2RX6 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (381 aa) | ||||
ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (890 aa) | ||||
GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1462 aa) | ||||
P2RX2 | P2X purinoceptor 2; Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity); Belongs to the P2X receptor family. (411 aa) | ||||
PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa) | ||||
PSKH1 | Protein serine kinase H1; Belongs to the protein kinase superfamily. (424 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) | ||||
H0VR18_CAVPO | Ig-like domain-containing protein. (136 aa) | ||||
CHRM2 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa) | ||||
ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1336 aa) | ||||
CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa) | ||||
PDE1B | Phosphodiesterase. (535 aa) | ||||
PLCD4 | Phosphoinositide phospholipase C. (762 aa) | ||||
EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa) | ||||
P2rx5 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (456 aa) | ||||
MCU | Mitochondrial calcium uniporter. (344 aa) | ||||
RYR1 | Ryanodine receptor 1. (4554 aa) | ||||
Lhcgr | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (691 aa) | ||||
TNNC2 | Troponin C2, fast skeletal type. (160 aa) | ||||
BSCL2 | BSCL2 lipid droplet biogenesis associated, seipin. (366 aa) | ||||
TACR3 | Neuromedin-K receptor; This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. (404 aa) | ||||
CYSLTR2 | Cysteinyl leukotriene receptor 2. (317 aa) | ||||
P2RX3 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa) | ||||
PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa) | ||||
H0VXJ2_CAVPO | Uncharacterized protein. (240 aa) | ||||
OTOP1 | Otopetrin 1. (578 aa) | ||||
CCKBR | Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa) | ||||
H0VZI8_CAVPO | Ig-like domain-containing protein. (123 aa) | ||||
H0W0D3_CAVPO | Ig-like domain-containing protein. (126 aa) | ||||
H0WDE0_CAVPO | Ig-like domain-containing protein. (118 aa) | ||||
EFCAB3 | EF-hand calcium binding domain 3. (436 aa) | ||||
CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa) | ||||
ADORA2A | Adenosine receptor A2a; Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). (409 aa) | ||||
PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa) | ||||
GNA11 | G protein subunit alpha 11. (345 aa) | ||||
LOC100732158 | Uncharacterized protein. (246 aa) | ||||
ENSCPOP00000022167 | Ig-like domain-containing protein. (174 aa) | ||||
ENSCPOP00000022622 | Ig-like domain-containing protein. (129 aa) | ||||
ENSCPOP00000022635 | Uncharacterized protein. (311 aa) | ||||
ORAI3 | ORAI calcium release-activated calcium modulator 3. (297 aa) | ||||
PHKA2 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1235 aa) | ||||
ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa) | ||||
ADRA1D | Adrenoceptor alpha 1D. (478 aa) | ||||
CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (545 aa) | ||||
CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa) | ||||
CAMKV | CaM kinase like vesicle associated. (506 aa) | ||||
RCSD1 | RCSD domain containing 1. (408 aa) | ||||
MCOLN3 | Mucolipin 3. (553 aa) | ||||
PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa) | ||||
ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa) | ||||
ENSCPOP00000023578 | Ig-like domain-containing protein. (129 aa) | ||||
ENSCPOP00000023636 | Ig-like domain-containing protein. (129 aa) | ||||
ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (221 aa) | ||||
HTR7 | 5-hydroxytryptamine receptor 7; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (337 aa) | ||||
ENSCPOP00000023749 | Uncharacterized protein. (244 aa) | ||||
CALML4 | Calmodulin like 4. (153 aa) | ||||
ENSCPOP00000023778 | Ig-like domain-containing protein. (179 aa) | ||||
ENSCPOP00000023913 | Ig-like domain-containing protein. (122 aa) | ||||
ENSCPOP00000024109 | DUF1968 domain-containing protein. (138 aa) | ||||
H0VVB6_CAVPO | Ig-like domain-containing protein. (137 aa) | ||||
ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa) | ||||
CAMK1D | Calcium/calmodulin dependent protein kinase ID. (381 aa) | ||||
ENSCPOP00000024624 | Uncharacterized protein. (493 aa) | ||||
F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa) | ||||
PHKA1 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1237 aa) | ||||
LOC100714922 | Ion_trans domain-containing protein. (685 aa) | ||||
PTGER1 | Prostaglandin E receptor 1. (405 aa) | ||||
DRD1 | Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa) | ||||
NOS1 | Nitric oxide synthase 1. (1465 aa) | ||||
ENSCPOP00000025410 | Ig-like domain-containing protein. (118 aa) | ||||
SPHK2 | Sphingosine kinase 2. (655 aa) | ||||
ENSCPOP00000025793 | Ig-like domain-containing protein. (146 aa) | ||||
ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) | ||||
STIM1 | Stromal interaction molecule 1. (713 aa) | ||||
VDAC2 | Voltage dependent anion channel 2. (294 aa) | ||||
TRBV24-1 | T cell receptor beta variable 24-1. (133 aa) | ||||
ENSCPOP00000026228 | Ig-like domain-containing protein. (134 aa) | ||||
PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) | ||||
TRBV19 | T cell receptor beta variable 19. (129 aa) | ||||
PTGER3 | Prostaglandin E receptor 3. (363 aa) | ||||
GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (943 aa) | ||||
PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) | ||||
GNAQ | G protein subunit alpha q. (313 aa) | ||||
TRDN | Triadin. (682 aa) | ||||
ENSCPOP00000027199 | Ig-like domain-containing protein. (128 aa) | ||||
CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (346 aa) | ||||
GRIN2D | Glutamate ionotropic receptor NMDA type subunit 2D. (808 aa) | ||||
RYR2 | Ryanodine receptor 2. (4910 aa) | ||||
LOC100729898 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (366 aa) | ||||
CACNA1G | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa) | ||||
LOC100718831 | YccV-like domain-containing protein. (514 aa) | ||||
BDKRB2 | B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (399 aa) | ||||
ADRA1B | Adrenoceptor alpha 1B. (520 aa) | ||||
Gpr150 | Uncharacterized protein. (388 aa) | ||||
DRD5 | Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa) | ||||
H0WAR2_CAVPO | Ig-like domain-containing protein. (139 aa) | ||||
H0WAH0_CAVPO | Ig-like domain-containing protein. (121 aa) | ||||
CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa) | ||||
ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa) | ||||
H0W813_CAVPO | Uncharacterized protein. (753 aa) | ||||
PHKG2 | Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa) | ||||
CHRM1 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa) | ||||
ARSI | Arylsulfatase family member I. (572 aa) | ||||
H0W6K2_CAVPO | Ig-like domain-containing protein. (135 aa) | ||||
ORAI1 | ORAI calcium release-activated calcium modulator 1. (302 aa) | ||||
P2rx7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa) | ||||
ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. (418 aa) | ||||
CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1774 aa) | ||||
ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1296 aa) | ||||
ADRB1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (470 aa) | ||||
TRGC1 | Ig-like domain-containing protein. (166 aa) | ||||
ATP2C2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (945 aa) | ||||
HRH1 | Histamine H1 receptor; In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. (482 aa) | ||||
Chrm3 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa) | ||||
CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (659 aa) |