STRINGSTRING
PIK3C2A PIK3C2A IPMK IPMK DGKK DGKK ITPKA ITPKA MTMR4 MTMR4 PRKCB PRKCB PIP5K1B PIP5K1B PIK3C3 PIK3C3 PI4K2A PI4K2A SHROOM4 SHROOM4 LOC100725517 LOC100725517 PIP4K2B PIP4K2B PIK3C2B PIK3C2B SAMSN1 SAMSN1 DGKH DGKH PIK3CA PIK3CA PLCZ1 PLCZ1 PLCD3 PLCD3 MTMR6 MTMR6 PIP4K2A PIP4K2A ASB12 ASB12 PIK3R1 PIK3R1 IP6K2 IP6K2 H0VB67_CAVPO H0VB67_CAVPO PLS3 PLS3 SACM1L SACM1L MTMR2 MTMR2 INPP5B INPP5B INPP5F INPP5F ITPKC ITPKC H0VEA9_CAVPO H0VEA9_CAVPO DGKD DGKD INPP5E INPP5E PLCE1 PLCE1 INSC INSC DGKA DGKA TNS4 TNS4 H0VGL3_CAVPO H0VGL3_CAVPO MTMR14 MTMR14 PI4KB PI4KB IPPK IPPK MTMR7 MTMR7 H0VKV0_CAVPO H0VKV0_CAVPO ITPR2 ITPR2 TASOR TASOR PIK3CD PIK3CD IP6K3 IP6K3 MTMR10 MTMR10 ITPKB ITPKB OCRL OCRL CALML3 CALML3 CENPF CENPF PRKCA PRKCA INPP5A INPP5A PLCD4 PLCD4 PIP4K2C PIP4K2C UNCX UNCX BSCL2 BSCL2 PLCG1 PLCG1 H0W027_CAVPO H0W027_CAVPO LOC100721187 LOC100721187 H0W3F4_CAVPO H0W3F4_CAVPO PI4KA PI4KA PTEN PTEN CDS2 CDS2 ITPR3 ITPR3 IMPA1 IMPA1 TNS2 TNS2 H0WBQ2_CAVPO H0WBQ2_CAVPO IMPAD1 IMPAD1 EFCAB3 EFCAB3 SASH1 SASH1 PLCB3 PLCB3 DGKI DGKI SYNJ1 SYNJ1 PI4K2B PI4K2B PPIP5K2 PPIP5K2 PIP4P1 PIP4P1 PSORS1C2 PSORS1C2 PLCB1 PLCB1 PIP4P2 PIP4P2 CALML4 CALML4 PIKFYVE PIKFYVE PRKCG PRKCG CDS1 CDS1 DGKZ DGKZ IP6K1 IP6K1 INPP4A INPP4A INPP4B INPP4B INPPL1 INPPL1 INPP1 INPP1 DGKE DGKE CALM3 CALM3 PLCD1 PLCD1 RBM18 RBM18 TNS1 TNS1 BICD2 BICD2 PLCB4 PLCB4 PLCB2 PLCB2 INPP5D INPP5D DGKQ DGKQ DGKG DGKG LOC101788042 LOC101788042 LOC100734206 LOC100734206 SYNJ2 SYNJ2 SAMD5 SAMD5 ITPR1 ITPR1 TNS3 TNS3 PLS1 PLS1 MTM1 MTM1 CDIPT CDIPT LRRN4CL LRRN4CL ENSCPOP00000032059 ENSCPOP00000032059 ITPK1 ITPK1 SBF1 SBF1 SBF2 SBF2 MTMR3 MTMR3 CALM1 CALM1 PLCG2 PLCG2 PIP5K1A PIP5K1A PIP5K1C PIP5K1C LCP1 LCP1 MTMR12 MTMR12 PPIP5K1 PPIP5K1 CALM2 CALM2 BICD1 BICD1 IMPA2 IMPA2 SASH3 SASH3 PIK3CB PIK3CB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1404 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (377 aa)
DGKKDiacylglycerol kinase. (1062 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (434 aa)
MTMR4Myotubularin related protein 4. (1189 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (488 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
PI4K2API3K/PI4K domain-containing protein. (479 aa)
SHROOM4Shroom family member 4. (1534 aa)
LOC100725517Myotubularin phosphatase domain-containing protein. (355 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (362 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1633 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (365 aa)
DGKHDiacylglycerol kinase. (1144 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa)
PLCZ1Phosphoinositide phospholipase C. (601 aa)
PLCD3Phosphoinositide phospholipase C. (785 aa)
MTMR6Myotubularin related protein 6. (620 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa)
ASB12Ankyrin repeat and SOCS box containing 12. (307 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (449 aa)
H0VB67_CAVPOPhosphatidylinositol 3-kinase catalytic subunit type 3. (651 aa)
PLS3Plastin 3. (637 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (587 aa)
MTMR2Myotubularin related protein 2. (643 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (983 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1107 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (679 aa)
H0VEA9_CAVPORTC domain-containing protein. (140 aa)
DGKDDiacylglycerol kinase. (1160 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (646 aa)
PLCE1Phosphoinositide phospholipase C. (2282 aa)
INSCINSC spindle orientation adaptor protein. (532 aa)
DGKADiacylglycerol kinase. (736 aa)
TNS4Tensin 4. (700 aa)
H0VGL3_CAVPOASD2 domain-containing protein. (446 aa)
MTMR14Myotubularin related protein 14. (649 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (828 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (489 aa)
MTMR7Myotubularin related protein 7. (640 aa)
H0VKV0_CAVPOUncharacterized protein; Belongs to the calmodulin family. (139 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
TASORTranscription activation suppressor. (1362 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (401 aa)
MTMR10Myotubularin related protein 10. (753 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (890 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (900 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
CENPFCentromere protein F. (3022 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (390 aa)
PLCD4Phosphoinositide phospholipase C. (762 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (419 aa)
UNCXUNC homeobox. (619 aa)
BSCL2BSCL2 lipid droplet biogenesis associated, seipin. (366 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa)
H0W027_CAVPOUncharacterized protein. (722 aa)
LOC100721187Uncharacterized protein. (489 aa)
H0W3F4_CAVPOMyotubularin phosphatase domain-containing protein. (121 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2064 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
TNS2Tensin 2. (1396 aa)
H0WBQ2_CAVPOUncharacterized protein. (282 aa)
IMPAD1Inositol monophosphatase domain containing 1. (355 aa)
EFCAB3EF-hand calcium binding domain 3. (436 aa)
SASH1SAM and SH3 domain containing 1. (1232 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
DGKIDiacylglycerol kinase. (957 aa)
SYNJ1Synaptojanin 1. (1607 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (469 aa)
PPIP5K2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1237 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
PSORS1C2Psoriasis susceptibility 1 candidate 2. (138 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
CALML4Calmodulin like 4. (153 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2079 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (422 aa)
DGKZDiacylglycerol kinase. (1118 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (433 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (972 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (939 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1267 aa)
INPP1Inositol polyphosphate-1-phosphatase. (526 aa)
DGKEDiacylglycerol kinase. (575 aa)
CALM3Calmodulin 3. (149 aa)
PLCD1Phosphoinositide phospholipase C. (755 aa)
RBM18RNA binding motif protein 18. (190 aa)
TNS1Tensin 1. (1593 aa)
BICD2BICD cargo adaptor 2. (856 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1220 aa)
DGKQDiacylglycerol kinase. (947 aa)
DGKGDiacylglycerol kinase. (792 aa)
LOC101788042C2 domain-containing protein. (110 aa)
LOC100734206Uncharacterized protein. (461 aa)
SYNJ2Synaptojanin 2. (1489 aa)
SAMD5Sterile alpha motif domain containing 5. (171 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
TNS3Tensin 3. (1562 aa)
PLS1Plastin 1. (630 aa)
MTM1Myotubularin 1. (599 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
LRRN4CLLRRN4 C-terminal like. (226 aa)
ENSCPOP00000032059Uncharacterized protein; Belongs to the calmodulin family. (73 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (419 aa)
SBF1SET binding factor 1. (1892 aa)
SBF2SET binding factor 2. (1875 aa)
MTMR3Myotubularin related protein 3. (1221 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (194 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (536 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (689 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
MTMR12Myotubularin related protein 12. (747 aa)
PPIP5K1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1415 aa)
CALM2Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa)
BICD1BICD cargo adaptor 1. (975 aa)
IMPA2Inositol-1-monophosphatase. (283 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: medium (44%) [HD]