STRINGSTRING
PPP2R1B PPP2R1B YWHAB YWHAB PPP2CA PPP2CA MAPK3 MAPK3 MAPK11 MAPK11 Pgr Pgr CALML4 CALML4 PPP1CB PPP1CB PPP2R5A PPP2R5A PPP1CA PPP1CA RPS6KA1 RPS6KA1 ANAPC10 ANAPC10 CAMK2G CAMK2G RPS6KA3 RPS6KA3 RPS6KA2 RPS6KA2 MAPK14 MAPK14 YWHAH YWHAH H0WDH3_CAVPO H0WDH3_CAVPO EFCAB3 EFCAB3 H0WBA3_CAVPO H0WBA3_CAVPO ITPR3 ITPR3 SGO1 SGO1 ARSI ARSI Cpeb1 Cpeb1 MAD2L2 MAD2L2 CAMK2B CAMK2B H0W160_CAVPO H0W160_CAVPO CCNB2 CCNB2 CUL1 CUL1 SPDYA SPDYA MOS MOS PPP2R5B PPP2R5B AR AR LOC100720222 LOC100720222 H0VW22_CAVPO H0VW22_CAVPO ANAPC7 ANAPC7 CPEB4 CPEB4 MAPK12 MAPK12 MAPK13 MAPK13 ADCY4 ADCY4 SMC1B SMC1B CALML3 CALML3 ADCY5 ADCY5 Anapc11 Anapc11 Ccne2 Ccne2 STAG3 STAG3 BUB1 BUB1 ANAPC4 ANAPC4 MAPK1 MAPK1 AURKC AURKC ITPR2 ITPR2 H0VKV0_CAVPO H0VKV0_CAVPO TMEM82 TMEM82 ANAPC5 ANAPC5 YWHAQ YWHAQ PPP2R5D PPP2R5D ADCY2 ADCY2 CDC23 CDC23 CDK2 CDK2 PPP3CA PPP3CA ANAPC2 ANAPC2 SMC1A SMC1A SMC3 SMC3 LOC100734047 LOC100734047 PKMYT1 PKMYT1 REC8 REC8 PPP3CB PPP3CB H0VBD1_CAVPO H0VBD1_CAVPO FBXO5 FBXO5 ADCY8 ADCY8 PLCZ1 PLCZ1 CAMK2A CAMK2A Aurka Aurka CDC20 CDC20 PPP1CC PPP1CC ADCY3 ADCY3 PTRHD1 PTRHD1 BTRC BTRC Cdk1 Cdk1 IGF1R IGF1R CDC16 CDC16 PPP2CB PPP2CB SKP1 SKP1 CCNE1 CCNE1 MAP2K1 MAP2K1 ADCY1 ADCY1 MAD1L1 MAD1L1 CALM1 CALM1 FBXO43 FBXO43 CALM2 CALM2 CPEB2 CPEB2 ESPL1 ESPL1 PPP3CC PPP3CC SLK SLK PPP2R5C PPP2R5C CDC20B CDC20B YWHAZ YWHAZ PPP2R5E PPP2R5E RBX1 RBX1 ADCY9 ADCY9 PRKACB PRKACB AURKB AURKB INS INS YWHAG YWHAG ADCY6 ADCY6 CDC26 CDC26 ADCY7 ADCY7 CALM3 CALM3 ENSCPOP00000028113 ENSCPOP00000028113 ANAPC13 ANAPC13 ANAPC1 ANAPC1 ENSCPOP00000029129 ENSCPOP00000029129 ENSCPOP00000029251 ENSCPOP00000029251 Ywhae Ywhae ITPR1 ITPR1 Camk2d Camk2d ENSCPOP00000030705 ENSCPOP00000030705 CPEB3 CPEB3 ENSCPOP00000030888 ENSCPOP00000030888 PLK1 PLK1 Ccnb1 Ccnb1 FBXW11 FBXW11 Pttg1 Pttg1 CDC27 CDC27 MAD2L1 MAD2L1 IGF1 IGF1 PPP3R1 PPP3R1 ENSCPOP00000032059 ENSCPOP00000032059 Prkaca Prkaca
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (696 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
MAPK11Mitogen-activated protein kinase. (385 aa)
PgrUncharacterized protein. (428 aa)
CALML4Calmodulin like 4. (153 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (545 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
YWHAH14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
H0WDH3_CAVPO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
EFCAB3EF-hand calcium binding domain 3. (436 aa)
H0WBA3_CAVPOUncharacterized protein. (184 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2663 aa)
SGO1Shugoshin 1. (522 aa)
ARSIArylsulfatase family member I. (572 aa)
Cpeb1RRM domain-containing protein. (560 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (659 aa)
H0W160_CAVPOUncharacterized protein. (589 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (295 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (357 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
ARAndrogen receptor. (926 aa)
LOC100720222Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (423 aa)
H0VW22_CAVPOProtein kinase domain-containing protein. (399 aa)
ANAPC7Anaphase promoting complex subunit 7. (555 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (636 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
SMC1BStructural maintenance of chromosomes protein. (1233 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa)
Anapc11RING-type domain-containing protein. (84 aa)
Ccne2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (405 aa)
STAG3Stromal antigen 3. (1219 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1031 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (257 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2622 aa)
H0VKV0_CAVPOUncharacterized protein; Belongs to the calmodulin family. (139 aa)
TMEM82Transmembrane protein 82. (356 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
CDC23Cell division cycle 23. (597 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PPP3CASerine/threonine-protein phosphatase. (518 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (827 aa)
SMC1AStructural maintenance of chromosomes protein. (1222 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
LOC100734047Uncharacterized protein. (567 aa)
PKMYT1Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily. (490 aa)
REC8REC8 meiotic recombination protein. (599 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
H0VBD1_CAVPO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (105 aa)
FBXO5F-box protein 5. (450 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
PLCZ1Phosphoinositide phospholipase C. (601 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
AurkaProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (384 aa)
CDC20Cell division cycle 20. (499 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa)
Cdk1Protein kinase domain-containing protein. (240 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
CDC16Cell division cycle 16. (620 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
SKP1S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (162 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ADCY1Adenylate cyclase 1. (944 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (717 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (194 aa)
FBXO43F-box protein 43. (622 aa)
CALM2Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (564 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2115 aa)
PPP3CCSerine/threonine-protein phosphatase. (481 aa)
SLKSTE20-like serine/threonine-protein kinase; Mediates apoptosis and actin stress fiber dissolution. (1231 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (589 aa)
CDC20BCell division cycle 20B. (525 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
RBX1Ring-box 1. (108 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (339 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
CDC26Cell division cycle 26. (85 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
CALM3Calmodulin 3. (149 aa)
ENSCPOP0000002811314_3_3 domain-containing protein; Belongs to the 14-3-3 family. (231 aa)
ANAPC13Anaphase promoting complex subunit 13. (74 aa)
ANAPC1Anaphase promoting complex subunit 1. (1941 aa)
ENSCPOP00000029129Protein kinase domain-containing protein. (254 aa)
ENSCPOP00000029251Uncharacterized protein; Belongs to the SKP1 family. (147 aa)
Ywhae14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa)
Camk2dProtein kinase domain-containing protein. (532 aa)
ENSCPOP00000030705CYCLIN domain-containing protein; Belongs to the cyclin family. (341 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (588 aa)
ENSCPOP00000030888Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
Ccnb1annotation not available (423 aa)
FBXW11F-box and WD repeat domain containing 11. (530 aa)
Pttg1Uncharacterized protein. (198 aa)
CDC27Cell division cycle 27. (825 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (153 aa)
PPP3R1Uncharacterized protein. (169 aa)
ENSCPOP00000032059Uncharacterized protein; Belongs to the calmodulin family. (73 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (22%) [HD]