STRINGSTRING
PEX5L PEX5L SLC25A17 SLC25A17 ABCD3 ABCD3 EPHX4 EPHX4 PXMP2 PXMP2 ACSL4 ACSL4 NAT9 NAT9 MLYCD MLYCD AGPS AGPS HAO1 HAO1 Acsl1 Acsl1 Far1 Far1 NUDT12 NUDT12 Nudt8 Nudt8 PEX3 PEX3 PEX13 PEX13 MPV17L2 MPV17L2 PEX11B PEX11B ACSL3 ACSL3 PEX11A PEX11A GNPAT GNPAT EPHX2 EPHX2 ENSCPOP00000029603 ENSCPOP00000029603 PRDX1 PRDX1 NUDT13 NUDT13 DAO DAO PXDN PXDN MPV17L MPV17L NUDT19 NUDT19 ENSCPOP00000026165 ENSCPOP00000026165 DECR1 DECR1 DDO DDO Acaa1 Acaa1 EHHADH EHHADH PEX7 PEX7 PEX12 PEX12 HACL1 HACL1 PEX26 PEX26 ENSCPOP00000024929 ENSCPOP00000024929 ILVBL ILVBL PRDX3 PRDX3 FAR2 FAR2 NUDT7 NUDT7 PEX2 PEX2 MPV17 MPV17 PEX19 PEX19 ENSCPOP00000022046 ENSCPOP00000022046 MTCL1 MTCL1 SOD2 SOD2 SOD3 SOD3 GSTK1 GSTK1 MVK MVK PEX5 PEX5 PEX10 PEX10 Phyhd1 Phyhd1 PXMP4 PXMP4 ACOX3 ACOX3 PRDX2 PRDX2 CRAT CRAT NOS2 NOS2 PRDX5 PRDX5 Baat Baat PEX16 PEX16 KIAA0408 KIAA0408 DENND10 DENND10 ACOX1 ACOX1 PEX14 PEX14 SOD1 SOD1 ASCC3 ASCC3 IDH1 IDH1 ACSF2 ACSF2 ACOT8 ACOT8 H0VM53_CAVPO H0VM53_CAVPO CAT CAT H0VKT0_CAVPO H0VKT0_CAVPO Paox Paox PECR PECR ABCD1 ABCD1 SOGA1 SOGA1 CROT CROT CARMIL3 CARMIL3 ABCD2 ABCD2 HSD17B4 HSD17B4 AMACR AMACR PEX6 PEX6 HMGCL HMGCL IDH2 IDH2 BTBD8 BTBD8 AGXT AGXT HNRNPL HNRNPL H0VAK6_CAVPO H0VAK6_CAVPO HNRNPLL HNRNPLL PHYH PHYH PIPOX PIPOX HFM1 HFM1 SLC27A2 SLC27A2 LOC100732696 LOC100732696 PEX1 PEX1 C1orf146 C1orf146 EPHX3 EPHX3 FAM185A FAM185A BAAT BAAT ACOX2 ACOX2 DECR2 DECR2 HMGCLL1 HMGCLL1 ACSL5 ACSL5 PMVK PMVK LOC100719714 LOC100719714 XDH XDH ECI2 ECI2 ABCD4 ABCD4 MEST MEST PRDX4 PRDX4 PEX11G PEX11G SLC30A2 SLC30A2 HSDL2 HSDL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PEX5LPeroxisomal biogenesis factor 5 like. (650 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
ABCD3ATP binding cassette subfamily D member 3. (611 aa)
EPHX4Epoxide hydrolase 4. (362 aa)
PXMP2Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (194 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (707 aa)
NAT9N-acetyltransferase 9 (putative). (205 aa)
MLYCDMalonyl-CoA decarboxylase. (488 aa)
AGPSAlkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis. Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (658 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
Acsl1Long-chain-fatty-acid--CoA ligase 1; Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity). Preferentially uses palmitoleate, oleate and linoleate (By similarity). Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs); Belongs to the ATP-dependent AMP-binding enzyme family. (698 aa)
Far1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
NUDT12Nudix hydrolase 12. (462 aa)
Nudt8Nudix hydrolase domain-containing protein. (212 aa)
PEX3Peroxisomal biogenesis factor 3. (373 aa)
PEX13Peroxisomal biogenesis factor 13. (402 aa)
MPV17L2MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (210 aa)
PEX11BPeroxisomal biogenesis factor 11 beta. (259 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
PEX11APeroxisomal biogenesis factor 11 alpha. (246 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (680 aa)
EPHX2Epoxide hydrolase 2. (469 aa)
ENSCPOP00000029603Uncharacterized protein. (144 aa)
PRDX1Peroxiredoxin 1. (199 aa)
NUDT13Nudix hydrolase 13. (352 aa)
DAOD-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). (347 aa)
PXDNPeroxidasin. (1479 aa)
MPV17LUncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (196 aa)
NUDT19Nudix hydrolase 19. (379 aa)
ENSCPOP00000026165Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (485 aa)
DECR12,4-dienoyl-CoA reductase 1. (335 aa)
DDOD-aspartate oxidase. (341 aa)
Acaa1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
EHHADHEnoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
PEX12Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (358 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
PEX26Peroxisomal biogenesis factor 26. (305 aa)
ENSCPOP00000024929SCP2 domain-containing protein. (143 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (634 aa)
PRDX3Peroxiredoxin 3. (257 aa)
FAR2Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
NUDT7Nudix hydrolase 7. (256 aa)
PEX2Peroxisomal biogenesis factor 2. (304 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa)
PEX19Uncharacterized protein. (299 aa)
ENSCPOP00000022046Thiolase_N domain-containing protein. (103 aa)
MTCL1Microtubule crosslinking factor 1. (1642 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (246 aa)
GSTK1Glutathione S-transferase kappa. (226 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
PEX5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (538 aa)
PEX10Peroxisomal biogenesis factor 10. (325 aa)
Phyhd1Uncharacterized protein. (287 aa)
PXMP4Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (737 aa)
PRDX2Peroxiredoxin 2. (198 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
NOS2Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1149 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (217 aa)
BaatBile_Hydr_Trans domain-containing protein. (47 aa)
PEX16Peroxisomal membrane protein PEX16. (335 aa)
KIAA0408KIAA0408. (691 aa)
DENND10DENN domain containing 10. (357 aa)
ACOX1Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (660 aa)
PEX14Peroxisomal biogenesis factor 14. (374 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2185 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ACSF2Acyl-CoA synthetase family member 2. (618 aa)
ACOT8Acyl-CoA thioesterase 8. (324 aa)
H0VM53_CAVPOAMP-binding domain-containing protein. (696 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa)
H0VKT0_CAVPOUncharacterized protein. (394 aa)
PaoxAmino_oxidase domain-containing protein. (513 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4- dienoyl-CoA reductase activity. (302 aa)
ABCD1ATP binding cassette subfamily D member 1. (723 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1430 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (580 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1375 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
HSD17B4Uncharacterized protein. (713 aa)
AMACRAlpha-methylacyl-CoA racemase. (383 aa)
PEX6Peroxisomal biogenesis factor 6. (982 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
BTBD8BTB domain containing 8. (1400 aa)
AGXTSerine--pyruvate aminotransferase. (414 aa)
HNRNPLHeterogeneous nuclear ribonucleoprotein L. (586 aa)
H0VAK6_CAVPOUncharacterized protein. (177 aa)
HNRNPLLHeterogeneous nuclear ribonucleoprotein L like. (580 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (336 aa)
PIPOXPipecolic acid and sarcosine oxidase. (390 aa)
HFM1Helicase for meiosis 1. (1400 aa)
SLC27A2Solute carrier family 27 member 2. (619 aa)
LOC100732696Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
PEX1Peroxisomal biogenesis factor 1. (1271 aa)
C1orf146Chromosome 1 open reading frame 146. (153 aa)
EPHX3Epoxide hydrolase 3. (314 aa)
FAM185AFamily with sequence similarity 185 member A. (388 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (419 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (709 aa)
DECR22,4-dienoyl-CoA reductase 2. (292 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (307 aa)
ACSL5AMP-binding domain-containing protein. (682 aa)
PMVKPhosphomevalonate kinase. (192 aa)
LOC100719714Uncharacterized protein. (279 aa)
XDHXanthine dehydrogenase. (1333 aa)
ECI2Enoyl-CoA delta isomerase 2. (354 aa)
ABCD4ATP binding cassette subfamily D member 4. (602 aa)
MESTMesoderm specific transcript. (335 aa)
PRDX4Peroxiredoxin 4. (270 aa)
PEX11GPeroxisomal biogenesis factor 11 gamma. (243 aa)
SLC30A2Solute carrier family 30 member 2. (365 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (440 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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