STRINGSTRING
JUN JUN LAMB1 LAMB1 SOS2 SOS2 ACTB ACTB RAC1 RAC1 PAK2 PAK2 BIRC3 BIRC3 PPP1CA PPP1CA TLN2 TLN2 LOC100713271 LOC100713271 VAV2 VAV2 PPP1CB PPP1CB DIAPH1 DIAPH1 PAK3 PAK3 IBSP IBSP ENSCPOP00000024053 ENSCPOP00000024053 ENSCPOP00000024144 ENSCPOP00000024144 MAPK3 MAPK3 PRKCG PRKCG MAPK8 MAPK8 ENSCPOP00000024624 ENSCPOP00000024624 ACTN4 ACTN4 MAPK9 MAPK9 THBS3 THBS3 FYN FYN ITGB7 ITGB7 ITGA6 ITGA6 AKT1 AKT1 ITGB4 ITGB4 Vegfa Vegfa ARHGAP5 ARHGAP5 PGF PGF TGFB1I1 TGFB1I1 CCND1 CCND1 Cav2 Cav2 FLNA FLNA BCAR1 BCAR1 CAV1 CAV1 CRKL CRKL COL9A1 COL9A1 MST1R MST1R ACTN1 ACTN1 PARVA PARVA MYL12A MYL12A FLNC FLNC ENSCPOP00000028762 ENSCPOP00000028762 COL6A6 COL6A6 GPATCH8 GPATCH8 DHX9 DHX9 COL6A2 COL6A2 ENSCPOP00000029275 ENSCPOP00000029275 VEGFB VEGFB LOC100734206 LOC100734206 VCL VCL Tnxb Tnxb ACTG1 ACTG1 CAV3 CAV3 PPP1R12B PPP1R12B COL6A3 COL6A3 VEGFC VEGFC NEDD9 NEDD9 RHOA RHOA MYLK2 MYLK2 AKT2 AKT2 CDC42 CDC42 GRB2 GRB2 BRAF BRAF MFF MFF RELN RELN Col9a3 Col9a3 SOS1 SOS1 PIP5K1A PIP5K1A PIP5K1C PIP5K1C RAF1 RAF1 PTK2 PTK2 VWF VWF PIK3CB PIK3CB COL2A1 COL2A1 EGF EGF Gp2 Gp2 COL4A4 COL4A4 VAV3 VAV3 HGF HGF PXN PXN TLN1 TLN1 MYLK4 MYLK4 PAK1 PAK1 EGFR EGFR ELK3 ELK3 ITGB1 ITGB1 IGF1 IGF1 BCL2 BCL2 XIAP XIAP PARVG PARVG H0W0U4_CAVPO H0W0U4_CAVPO H0W027_CAVPO H0W027_CAVPO TNC TNC VWA2 VWA2 H0VX85_CAVPO H0VX85_CAVPO CAPN2 CAPN2 CCND3 CCND3 ACTRT2 ACTRT2 OTOGL OTOGL COL4A1 COL4A1 RAC2 RAC2 PARVB PARVB ITGA2 ITGA2 AKT3 AKT3 DOCK1 DOCK1 PDGFA PDGFA CHAD CHAD Rap1b Rap1b CTNNB1 CTNNB1 HRAS HRAS PDGFD PDGFD MAPK10 MAPK10 RAP1A RAP1A PPP1CC PPP1CC Bad Bad IGF1R IGF1R PDGFB PDGFB THBS4 THBS4 MYLK MYLK LAMC3 LAMC3 PIP5K1B PIP5K1B LAMB3 LAMB3 VEGFD VEGFD PPP1R12A PPP1R12A MYLK3 MYLK3 ITGA3 ITGA3 PDPK1 PDPK1 PRKCB PRKCB COL1A1 COL1A1 VTN VTN MYLPF MYLPF MAP2K1 MAP2K1 PPP1R14B PPP1R14B OTOG OTOG ITGA10 ITGA10 ITGAV ITGAV SSPO SSPO UMOD UMOD COL4A6 COL4A6 PRKCA PRKCA THBS1 THBS1 ITGA9 ITGA9 SPP1 SPP1 RHOC RHOC MYL9 MYL9 GSK3B GSK3B LAMA2 LAMA2 RAC3 RAC3 LRRC45 LRRC45 ITGA1 ITGA1 MET MET FLT1 FLT1 LAMA1 LAMA1 ARHGAP35 ARHGAP35 MAPK1 MAPK1 PIK3CD PIK3CD ITGA11 ITGA11 FN1 FN1 ROCK2 ROCK2 ILK ILK PDGFC PDGFC TNN TNN PDGFRA PDGFRA RPS6KL1 RPS6KL1 LPXN LPXN MST1 MST1 Itgb3 Itgb3 MYL2 MYL2 COL1A2 COL1A2 COL4A2 COL4A2 FLNB FLNB ROCK1 ROCK1 BIRC2 BIRC2 VASP VASP KDR KDR LAMB2 LAMB2 ITGA8 ITGA8 ITGB5 ITGB5 LAMA5 LAMA5 ITGA4 ITGA4 ELK1 ELK1 ITGB8 ITGB8 LAMC2 LAMC2 LAMC1 LAMC1 FLT4 FLT4 PIK3R1 PIK3R1 ITGA5 ITGA5 LAMA3 LAMA3 TNR TNR COL6A5 COL6A5 ITGA7 ITGA7 SRMS SRMS PTK6 PTK6 CRK CRK ITGA2B ITGA2B PIK3CA PIK3CA Shc4 Shc4 CEP152 CEP152 LAMA4 LAMA4 PDGFRB PDGFRB ACTL7A ACTL7A ERBB2 ERBB2 Ccnd2 Ccnd2 LOC100721187 LOC100721187 THBS2 THBS2 LOC100723025 LOC100723025 COMP COMP ACTL7B ACTL7B RAPGEF1 RAPGEF1 H0W2Y7_CAVPO H0W2Y7_CAVPO ACTRT1 ACTRT1 PAK6 PAK6 TLNRD1 TLNRD1 SHC3 SHC3 PTEN PTEN LOC100731872 LOC100731872 ITGB6 ITGB6 SHC1 SHC1 PAK4 PAK4 ACTL9 ACTL9 ZYX ZYX ACTL8 ACTL8 PPP1R12C PPP1R12C MYL10 MYL10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa)
LAMB1Laminin subunit beta 1. (1792 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
BIRC3Baculoviral IAP repeat containing 3. (600 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
TLN2Talin 2. (2542 aa)
LOC100713271Uncharacterized protein. (165 aa)
VAV2Vav guanine nucleotide exchange factor 2. (807 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
DIAPH1Diaphanous related formin 1. (1213 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
IBSPIntegrin binding sialoprotein. (323 aa)
ENSCPOP00000024053Uncharacterized protein. (948 aa)
ENSCPOP00000024144Protein kinase domain-containing protein. (110 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSCPOP00000024624Uncharacterized protein. (493 aa)
ACTN4Actinin alpha 4. (911 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
THBS3Thrombospondin 3. (956 aa)
FYNTyrosine-protein kinase. (537 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (809 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1158 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ITGB4Integrin beta. (1815 aa)
VegfaVascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa)
ARHGAP5Rho GTPase activating protein 5. (1501 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (168 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (125 aa)
FLNAFilamin A. (2645 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (879 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
MST1RMacrophage stimulating 1 receptor. (1504 aa)
ACTN1Actinin alpha 1. (914 aa)
PARVAParvin alpha. (347 aa)
MYL12AMyosin light chain 12A. (178 aa)
FLNCFilamin C. (2726 aa)
ENSCPOP00000028762Uncharacterized protein. (107 aa)
COL6A6Collagen type VI alpha 6 chain. (2269 aa)
GPATCH8G-patch domain containing 8. (1430 aa)
DHX9DExH-box helicase 9. (1373 aa)
COL6A2Collagen type VI alpha 2 chain. (1020 aa)
ENSCPOP00000029275VWFA domain-containing protein. (72 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (206 aa)
LOC100734206Uncharacterized protein. (461 aa)
VCLVinculin. (1134 aa)
TnxbUncharacterized protein. (3465 aa)
ACTG1Actin gamma 1. (375 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1053 aa)
COL6A3Collagen type VI alpha 3 chain. (2507 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (418 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
RHOARas homolog family member A. (193 aa)
MYLK2Myosin light chain kinase 2. (593 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CDC42Cell division cycle 42. (191 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (738 aa)
MFFMitochondrial fission factor. (354 aa)
RELNReelin. (3423 aa)
Col9a3Uncharacterized protein. (680 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1276 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (536 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (689 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
VWFUncharacterized protein. (2833 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1018 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1194 aa)
Gp2ZP domain-containing protein. (526 aa)
COL4A4Collagen type IV alpha 4 chain. (1686 aa)
VAV3Vav guanine nucleotide exchange factor 3. (779 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (588 aa)
TLN1Talin 1. (2537 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (386 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
EGFRReceptor protein-tyrosine kinase. (1214 aa)
ELK3ETS transcription factor ELK3. (402 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
IGF1Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...] (153 aa)
BCL2BCL2 apoptosis regulator. (183 aa)
XIAPX-linked inhibitor of apoptosis. (496 aa)
PARVGParvin gamma. (223 aa)
H0W0U4_CAVPOCalpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (420 aa)
H0W027_CAVPOUncharacterized protein. (722 aa)
TNCTenascin C. (2203 aa)
VWA2Von Willebrand factor A domain containing 2. (666 aa)
H0VX85_CAVPOUncharacterized protein. (184 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (211 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (376 aa)
OTOGLOtogelin like. (2177 aa)
COL4A1Collagen type IV alpha 1 chain. (1658 aa)
RAC2Ras-related C3 botulinum toxin substrate 2; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity). (192 aa)
PARVBParvin beta. (365 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa)
AKT3AKT serine/threonine kinase 3. (470 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1865 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (190 aa)
CHADChondroadherin. (359 aa)
Rap1bUncharacterized protein. (184 aa)
CTNNB1Catenin beta 1. (781 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PDGFDPlatelet derived growth factor D. (370 aa)
MAPK10Mitogen-activated protein kinase 10. (434 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
BadUncharacterized protein. (166 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
THBS4Thrombospondin 4. (958 aa)
MYLKMyosin light chain kinase. (1959 aa)
LAMC3Laminin subunit gamma 3. (1491 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (488 aa)
LAMB3Laminin subunit beta 3. (1174 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (348 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1069 aa)
MYLK3Myosin light chain kinase 3. (811 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1048 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (550 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (643 aa)
COL1A1Collagen type I alpha 1 chain. (1454 aa)
VTNSMB domain-containing protein. (482 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (108 aa)
OTOGOtogelin. (2777 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1164 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (963 aa)
SSPOSCO-spondin. (5059 aa)
UMODUromodulin. (644 aa)
COL4A6Collagen type IV alpha 6 chain. (1687 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (601 aa)
THBS1Thrombospondin 1. (1163 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1008 aa)
SPP1Secreted phosphoprotein 1. (263 aa)
RHOCRas homolog family member C. (193 aa)
MYL9Myosin light chain 9. (172 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
LAMA2Laminin subunit alpha 2. (3113 aa)
RAC3Rac family small GTPase 3. (192 aa)
LRRC45Leucine rich repeat containing 45. (669 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1168 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1332 aa)
LAMA1Laminin subunit alpha 1. (3018 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1188 aa)
FN1Fibronectin 1. (2478 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1371 aa)
ILKIntegrin-linked protein kinase; Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B. (452 aa)
PDGFCPlatelet derived growth factor C. (295 aa)
TNNTenascin N. (1473 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
RPS6KL1Ribosomal protein S6 kinase like 1. (634 aa)
LPXNLeupaxin. (381 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (712 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (735 aa)
MYL2Myosin light chain 2. (167 aa)
COL1A2Collagen type I alpha 2 chain. (1287 aa)
COL4A2Collagen type IV alpha 2 chain. (1479 aa)
FLNBFilamin B. (2602 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (376 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
LAMB2Laminin subunit beta 2. (1800 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LAMA5Laminin subunit alpha 5. (3609 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1021 aa)
ELK1ETS transcription factor ELK1. (422 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
LAMC2Laminin subunit gamma 2. (1189 aa)
LAMC1Laminin subunit gamma 1. (1557 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1343 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1102 aa)
LAMA3Laminin subunit alpha 3. (3262 aa)
TNRTenascin R. (1358 aa)
COL6A5Collagen type VI alpha 5 chain. (2558 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1137 aa)
SRMSTyrosine-protein kinase. (508 aa)
PTK6Tyrosine-protein kinase. (451 aa)
CRKCRK proto-oncogene, adaptor protein. (281 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1007 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa)
Shc4Uncharacterized protein. (372 aa)
CEP152Centrosomal protein 152. (1666 aa)
LAMA4Laminin subunit alpha 4. (1810 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
ACTL7AActin like 7A; Belongs to the actin family. (440 aa)
ERBB2Receptor protein-tyrosine kinase. (1256 aa)
Ccnd2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (288 aa)
LOC100721187Uncharacterized protein. (489 aa)
THBS2Thrombospondin 2. (1172 aa)
LOC100723025Uncharacterized protein. (431 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
ACTL7BActin like 7B; Belongs to the actin family. (412 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1263 aa)
H0W2Y7_CAVPOCalpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (380 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (377 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
TLNRD1Talin rod domain containing 1. (355 aa)
SHC3SHC adaptor protein 3. (418 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
LOC100731872Uncharacterized protein; Belongs to the actin family. (1226 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (788 aa)
SHC1SHC adaptor protein 1. (583 aa)
PAK4Non-specific serine/threonine protein kinase. (592 aa)
ACTL9Actin like 9; Belongs to the actin family. (388 aa)
ZYXUncharacterized protein. (383 aa)
ACTL8Actin like 8; Belongs to the actin family. (371 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit. (758 aa)
MYL10Myosin light chain 10. (147 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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